Abstract:
:Smokers have substantial individual differences in quit success in response to current treatments for nicotine dependence. This observation may suggest that different underlying motivations for continued tobacco use across individuals and nicotine cessation may require different treatments in different individuals. Although most animal models of nicotine dependence emphasize the positive reinforcing effects of nicotine as the major motivational force behind nicotine use, smokers generally report that other consequences of nicotine use, including the ability of nicotine to alleviate negative affective states or cognitive impairments, as reasons for continued smoking. These states could result from nicotine withdrawal, but also may be associated with premorbid differences in affective and/or cognitive function. Effects of nicotine on cognition and affect may alleviate these impairments regardless of their premorbid or postmorbid origin (e.g., before or after the development of nicotine dependence). The ability of nicotine to alleviate these symptoms would thus negatively reinforce behavior, and thus maintain subsequent nicotine use, contributing to the initiation of smoking, the progression to dependence and relapse during quit attempts. The human and animal studies reviewed here support the idea that self-medication for pre-morbid and withdrawal-induced impairments may be more important factors in nicotine addiction and relapse than has been previously appreciated in preclinical research into nicotine dependence. Given the diverse beneficial effects of nicotine under these conditions, individuals might smoke for quite different reasons. This review suggests that inter-individual differences in the diverse effects of nicotine associated with self-medication and negative reinforcement are an important consideration in studies attempting to understand the causes of nicotine addiction, as well as in the development of effective, individualized nicotine cessation treatments.
journal_name
Neurosci Biobehav Revjournal_title
Neuroscience and biobehavioral reviewsauthors
Hall FS,Der-Avakian A,Gould TJ,Markou A,Shoaib M,Young JWdoi
10.1016/j.neubiorev.2015.06.004subject
Has Abstractpub_date
2015-11-01 00:00:00pages
168-85eissn
0149-7634issn
1873-7528pii
S0149-7634(15)00158-Xjournal_volume
58pub_type
杂志文章,评审abstract::Pupillometry, measuring pupil size and reactivity, has been proposed as a measure of autonomic nervous system functioning, the latter which might be altered in individuals with autism spectrum disorder (ASD). This study aims to evaluate if pupillary responses differ in individuals with and without ASD. After performin...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2020.09.032
更新日期:2020-10-22 00:00:00
abstract::Human adolescence is a time of enormous developmental change, second only to infancy and early childhood in terms of brain shaping and growth. It is also a period in life when the young adult is faced with distinct environmental challenges and stressors. Interestingly, we now know that these external sources of stress...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2016.06.005
更新日期:2016-11-01 00:00:00
abstract::Recognition that posterior basal and medial parts of the prefrontal cortex belong to the cortical component of the limbic system was important in understanding their anatomic and functional organization. In primates, the limbic system has evolved along with the neocortex and maintains strong connections with associati...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/0149-7634(94)00053-4
更新日期:1995-10-01 00:00:00
abstract::The effects of a number of 5-HT receptor ligands were examined on nonopioid defensive analgesia in male DBA/2 mice. MDL 73005EF (0.05-1.0 mg/kg), a selective 5-HT1A receptor agonist, potently and dose-dependently inhibited the analgesic consequences of social defeat. CGS 12066B (0.5-10.0 mg/kg) and MK-212 (0.3-10.0 mg...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章
doi:10.1016/s0149-7634(05)80137-x
更新日期:1991-01-01 00:00:00
abstract::Major depressive disorder (MDD) is a devastating disease affecting over 300 million people worldwide, and costing an estimated 380 billion Euros in lost productivity and health care in the European Union alone. Although a wealth of research has been directed toward understanding and treating MDD, still no therapy has ...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2015.07.011
更新日期:2015-11-01 00:00:00
abstract::This paper aims to systematically review the influence of apolipoprotein E (ApoE) on the effects of potentially modifiable mid and late life risk factors for dementia. Scopus, Medline, PubMed, PsycINFO, and HuGE databases were searched up to November 2008. Two independent reviewers selected 94 articles from 13,122 res...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2009.08.007
更新日期:2010-03-01 00:00:00
abstract::Williams syndrome (WS) is a rare genetically based neurodevelopmental disorder which is associated with mental retardation and a distinctive cognitive and behavioural profile, including weaknesses in visuospatial processing but preserved language abilities and face recognition. Relative to the cognitive characteristic...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2007.09.003
更新日期:2008-01-01 00:00:00
abstract::The aim of this systematic review was to summarize the effects of physical exercise on neuropathic pain (NP) in animal models of SCI. The search was conducted in Medline and Science Direct to identify experimental preclinical studies involving animal models of SCI, physical exercise as an intervention and the assessme...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,meta分析
doi:10.1016/j.neubiorev.2019.12.016
更新日期:2020-01-01 00:00:00
abstract::The neural regulation of circulatory function is mainly effected through the interplay of the sympathetic and vagal outflows. This interaction can be explored by assessing cardiovascular rhythmicity with appropriate spectral methodologies. Spectral analysis of cardiovascular signal variability, and in particular of RR...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2008.07.006
更新日期:2009-02-01 00:00:00
abstract::A central premise of the science of comparative affect is that we can best learn about the causes and consequences of affect by comparing affective phenomena across a variety of species, including humans. We take as a given that affect is widely shared across animals, but a key challenge is to accurately represent eac...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2019.09.027
更新日期:2019-12-01 00:00:00
abstract::There is convincing evidence that schizophrenia is characterised by progressive brain volume changes during the course of the illness. In a large longitudinal study it was shown that different age-related trajectories of brain tissue loss are present in patients compared to healthy subjects, suggesting that brain matu...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2012.09.006
更新日期:2013-12-01 00:00:00
abstract::Neurobiological models of adolescent decision-making emphasize developmental changes in brain regions involved in affect (e.g., ventral striatum) and cognitive control (e.g., lateral prefrontal cortex). Although social context plays an important role in adolescent decision-making, current models do not discuss brain r...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.neubiorev.2018.12.024
更新日期:2019-06-01 00:00:00
abstract::This systematic review and meta-analysis was conducted across studies using transcranial magnetic stimulation to investigate corticospinal excitability and inhibition in response to a dual task (DT). Quantitative analysis was performed on eleven controlled studies that had included healthy participants over the age of...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.neubiorev.2014.03.017
更新日期:2014-06-01 00:00:00
abstract::The problems and issues associated with the use of pharmacological antagonists in studies on learning and memory are considered in a review of the role of N-methyl-D-aspartate (NMDA) receptors, NMDA receptor-mediated long-term potentiation (LTP), and muscarinic receptors in spatial learning in the water maze. The evid...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/s0149-7634(97)00005-5
更新日期:1998-03-01 00:00:00
abstract::Less than two decades after its inception, the burgeoning field of neuroaesthetics continues to grow in interest and momentum. Despite the biological and social importance of the human body and the attention people pay to its appearance in daily life, only recently has neuroaesthetic inquiry turned its attention to qu...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2015.12.005
更新日期:2016-03-01 00:00:00
abstract::Gilles de la Tourette Syndrome (TS) is a neuropsychiatric disorder that is caused by a likely complex genetic basis, interacting with environmental factors. Just as multiple large scale collaborative projects for TS are starting out and the first ever genomewide association study for TS has been published, this review...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2013.01.016
更新日期:2013-07-01 00:00:00
abstract::To understand the onset and the molecular mechanisms triggering dopaminergic (DA) dysregulation in Attention-Deficit Hyperactivity Disorder (ADHD), we have used the Spontaneously Hypertensive Rats (SHR), the most widely studied animal model for this disease. We have studied the pattern of expression of specific genes ...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2003.08.009
更新日期:2003-11-01 00:00:00
abstract::Among the most useful models for depressive disorders are those, which involve a stress induced change in behaviour. Learned helplessness is one such model and is induced through exposure to uncontrollable and unpredictable aversive events. Learned helplessness as induced in rats using foot shock is well characterized...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2005.03.019
更新日期:2005-01-01 00:00:00
abstract::This review critically evaluates the animal and human research concerning vasopressin's putative mnemonic role. Weaknesses in the interpretations of the early animal experiments as well as the implications of the later inconsistent findings are discussed. It is concluded that both the initial enthusiasm and the subseq...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/0149-7634(85)90018-1
更新日期:1985-10-01 00:00:00
abstract::Males of many animal species perform specialized courtship behaviours to gain copulations with females. Identifying physiological and anatomical specializations underlying performance of these behaviours helps clarify mechanisms through which sexual selection promotes the evolution of elaborate courtship. Our knowledg...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2014.07.017
更新日期:2014-10-01 00:00:00
abstract::The present review discusses the history and paradigm of the conditioned avoidance response (CAR) in rats for the detection of potential antipsychotic activity of drugs. In addition, the role of dopamine (DA) D2, serotonin (5-HT)2A/2C, alpha1, 5-HT1A, DA D4, muscarinic and glutamate receptors in the suppression of CAR...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/s0149-7634(99)00037-8
更新日期:1999-01-01 00:00:00
abstract::Emotional hyperthermia, circadian variations and the rise of body temperature related to exercise, have all been attributed to setpoint temperature shifts. The accepted theory holds that core temperature is regulated by corrective thermoregulatory responses opposing the core temperature deviations from the setpoint le...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/s0149-7634(97)00051-1
更新日期:1998-05-01 00:00:00
abstract::Smaller hippocampal volume is associated with increased risk for PTSD following trauma, but the hippocampal functions involved remain unknown. We propose a conceptual model that identifies broad impairment in hippocampus-dependent associative learning as a vulnerability factor for PTSD. Associative learning of foregro...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,meta分析
doi:10.1016/j.neubiorev.2019.09.024
更新日期:2019-12-01 00:00:00
abstract::For human and non-human primates, vision is one of the most privileged sensory channels used to interact with the environment. The importance of vision is strongly embedded in the organization of the primate brain as about one third of its cortical surface is involved in visual functions. It is therefore not surprisin...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2013.08.001
更新日期:2014-04-01 00:00:00
abstract::Abnormalities in the simplest form of learning, habituation, have been reported in a variety of neuropsychiatric disorders as etiologically diverse as Autism Spectrum Disorder, Fragile X syndrome, Schizophrenia, Parkinson's Disease, Huntington's Disease, Attention Deficit Hyperactivity Disorder, Tourette's Syndrome, a...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2017.05.028
更新日期:2017-09-01 00:00:00
abstract::Cyrulnik, S.C., and V.J. Hinton. Duchenne muscular dystrophy: A cerebellar disorder? NEUROSCI. BIOBEHAV. REV. Duchenne muscular dystrophy (DMD) is a genetic disorder that is often associated with cognitive deficits. These cognitive deficits have been linked to the absence of dystrophin, a protein product which is norm...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2007.09.001
更新日期:2008-01-01 00:00:00
abstract::Noting important recent discoveries, we review primate social learning, traditions and culture, together with associated findings about primate brains. We survey our current knowledge of primate cultures in the wild, and complementary experimental diffusion studies testing species' capacity to sustain traditions. We r...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2016.12.018
更新日期:2017-11-01 00:00:00
abstract::Chronic stress has been shown to promote numerous aging-related diseases, and to accelerate the aging process itself. Of particular interest is the impact of stress on Alzheimer's disease (AD), the most prevalent form of dementia. The vast majority of AD cases have no known genetic cause, making it vital to identify t...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2020.05.010
更新日期:2020-08-01 00:00:00
abstract::Defense patterns of rats and mice have been characterized in terms of the relationships between the type of defensive behavior (e.g. flight, freezing, hiding, defensive threat/attack, and risk assessment) and particular features of the eliciting (threat) stimulus and the situation in which it is encountered. Because t...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章
doi:10.1016/s0149-7634(01)00056-2
更新日期:2001-12-01 00:00:00
abstract::This study presents a comprehensive systematic review and meta-analysis of temporal processing in autism spectrum disorder (ASD) and developmental dyslexia (DD), two neurodevelopmental disorders in which temporal processing deficits have been highly researched. The results provide strong evidence for impairments in te...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2020.06.013
更新日期:2020-09-01 00:00:00