Abstract:
:The purpose of the present review is to correlate recent knowledge of the role of peripheral ionotropic glutamate receptors in the temporomandibular joint and muscle pain from animal and human experimental pain models with findings in patients. Chronic pain is common, and many people suffer from chronic pain conditions involving deep craniofacial tissues such as temporomandibular disorders or fibromyalgia. Animal and human studies have indicated that the activation of peripheral ionotropic glutamate receptors in deep craniofacial tissues may contribute to muscle and temporomandibular joint pain and that sex differences in the activation of glutamate receptors may be involved in the female predominance in temporomandibular disorders and fibromyalgia. A peripheral mechanism involving autocrine and/or paracrine regulation of nociceptive neuronal excitability via injury or inflammation-induced release of glutamate into peripheral tissues that may contribute to the development of craniofacial pain is proposed.
journal_name
Pain Res Managjournal_title
Pain research & managementauthors
Lam DK,Sessle BJ,Cairns BE,Hu JWdoi
10.1155/2005/860354subject
Has Abstractpub_date
2005-10-01 00:00:00pages
145-52issue
3eissn
1203-6765issn
1918-1523journal_volume
10pub_type
杂志文章,评审abstract:BACKGROUND:A relationship between smoking and development of pain syndromes has been suggested in the literature. The present study examined associations between smoke exposure and other related variables, and pain response to suprathreshold electrical stimulation. METHODS:Subjects were prospectively recruited from a ...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2008/240573
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:Pediatric chronic pain is a common problem with significant economic implications and devastating consequences on quality of life. The present report describes a case involving a 15-year-old girl with severe and debilitating chronic pain. RESULTS:Before her referral to a pain rehabilitation program, the pat...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2014/745458
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:To investigate the emotional and neurobehavioural status of patients suffering from chronic pain. METHODS:Fifteen male patients with chronic lower back pain and 15 healthy control subjects were studied for approximately six months. Pain was measured using a visual analogue scale. The WHO Neurobehavioral Core...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2011/825636
更新日期:2011-01-01 00:00:00
abstract::Context. Postthoracotomy Ipsilateral Shoulder Pain (IPS) is a common and sometimes intractable pain syndrome. IPS is different from chest wall pain in type, origin, and treatments. Various treatments are suggested or applied for it but none of them is regarded as popular accepted effective one. Objectives. To review d...
journal_title:Pain research & management
pub_type: 杂志文章,评审
doi:10.1155/2016/3652726
更新日期:2016-01-01 00:00:00
abstract:Objective:To assess the validity of an exposure score obtained from the Xm2 tool for all pharmacological and nonpharmacological strategies used by individuals to manage chronic pain. Methods:Using data from individuals with chronic pain, eXposure multimodal (Xm2) scores were calculated by assigning one point for every...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2018/2530286
更新日期:2018-12-12 00:00:00
abstract::Background. Dexamethasone is sometimes used as a coanalgesic because of its anti-inflammatory properties. Objective. To evaluate opioid use, postoperative pain intensity, and side effects after a single dose of dexamethasone in patients undergoing arthroscopic knee surgery. Methods. In this randomized controlled study...
journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
doi:10.1155/2016/4216469
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Dynamic mechanical allodynia is traditionally induced by manual brushing of the skin. Brushing force and speed have been shown to influence the intensity of brush-evoked pain. There are still limited data available with respect to the optimal stroke number, length, force, angle and speed. Therefore, an autom...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2013/142582
更新日期:2013-01-01 00:00:00
abstract::Neuropathic pain (NeP), generated by disorders of the peripheral and central nervous system, can be particularly severe and disabling. Prevalence estimates indicate that 2% to 3% of the population in the developed world suffer from NeP, which suggests that up to one million Canadians have this disabling condition. Evi...
journal_title:Pain research & management
pub_type: 共识发展会议,杂志文章,实务指引
doi:10.1155/2007/730785
更新日期:2007-04-01 00:00:00
abstract::Background. In order to better design awareness programs on chronic pain (CP), measurement of knowledge, beliefs, and attitudes of people in the community towards this condition is most useful. Objectives. To develop and validate a French-Canadian scale that could be used for this purpose. Methods. Items of the Chroni...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2016/5940206
更新日期:2016-01-01 00:00:00
abstract::The Ways of Coping Questionnaire (WCQ) is a widely used measure of coping processes. Despite its use in a variety of populations, there has been concern about the stability and structure of the WCQ across different populations. This study examines the factor structure of the WCQ in a large sample of individuals diagno...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2016/7297826
更新日期:2016-01-01 00:00:00
abstract:Objective:This study aimed at assessing the clinical effectiveness of acupuncture for lateral epicondylitis (LE). Methods:The following databases were systematically searched: China National Knowledge Infrastructure, Chinese Science and Technology Periodical Database, Wan Fang database, Chinese Biomedicine Literature,...
journal_title:Pain research & management
pub_type: 杂志文章,meta分析
doi:10.1155/2020/8506591
更新日期:2020-03-20 00:00:00
abstract:Objectives:A recent work has reported that the elevated osteopontin (OPN) levels in the articular cartilage and synovial fluid are correlated with the progressive osteoarthritis (OA) joint damage, and OPN has a protective effect against OA by suppressing the expressions of OA-associated genes. The present study examine...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2020/3428587
更新日期:2020-10-22 00:00:00
abstract:Purpose:The purpose of this study was to investigate the prevalence of sleep disturbance and its clinical implication in patients with ASD. Methods:A total of 44 patients with ASD and 137 patients with lumbar spinal stenosis (LSS) were enrolled in the study. Forty four patients were selected from the LSS group after p...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2020/6294151
更新日期:2020-04-13 00:00:00
abstract:BACKGROUND:Acetaminophen is one of the most common drugs used for the treatment of pain and fever. OBJECTIVES:To examine the effects of intra-articular (IA) acetaminophen on carrageenan-induced arthritic pain-related behaviour and spinal c-Fos expression in rats. METHODS:The present study was performed using 20 Sprag...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2013/148392
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Pain clinics tend to see more complex chronic pain patients than primary care settings, but the types of patients seen may differ among practices. OBJECTIVE:The aim of the present observational study was to describe the pain and demographic characteristics of patients attending a university-affiliated terti...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2007/658762
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:A pilot study was conducted to assess whether both the rationale and feasibility exist for future randomized clinical trials to evaluate the combined use of naloxone infusion and tramadol/acetaminophen as opioid-sparing drugs in elderly patients undergoing lower extremity joint replacement surgery. DESIGN:Te...
journal_title:Pain research & management
pub_type: 临床试验,杂志文章
doi:10.1155/2009/497217
更新日期:2009-03-01 00:00:00
abstract:Background and Objective:A novel option for myofascial pain (MFP) management and muscle regeneration is intramuscular collagen injections. The aim of the study was to evaluate the efficiency of intramuscular injections of collagen and lidocaine in decreasing MFP within masseter muscles. Methods:Myofascial pain within ...
journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
doi:10.1155/2018/8261090
更新日期:2018-06-03 00:00:00
abstract:OBJECTIVE:To investigate the status of work-related musculoskeletal disorders (WMSDs) in nurses working in the hospitals in Xinjiang Uygur Autonomous Region. METHODS:The prevalence of WMSDs since working and in the previous 12 months was evaluated using self-administrated modified musculoskeletal questionnaire based o...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2017/5757108
更新日期:2017-01-01 00:00:00
abstract:Objective:The aim of this study was to estimate the incidence of delirium and its risk factors among critically ill cancer patients in an intensive care unit (ICU). Materials and Methods:This is a prospective cohort study. The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) was measured daily at morn...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2018/4193275
更新日期:2018-07-08 00:00:00
abstract::Several research studies have revealed that migraine has a solid link with gastrointestinal diseases especially irritable bowel syndrome (IBS). This study was carried out to investigate therapeutic potential of diet based on IgG elimination combined with probiotics on migraine plus irritable bowel syndrome. A total of...
journal_title:Pain research & management
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1155/2019/7890461
更新日期:2019-08-21 00:00:00
abstract:BACKGROUND:Facial responses to pain are believed to be an act of communication and, as such, are likely to be affected by the relationship between sender and receiver. OBJECTIVES:To investigate this effect by examining the impact that variations in communicative relations (from being alone to being with an intimate ot...
journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
doi:10.1155/2014/195286
更新日期:2014-01-01 00:00:00
abstract::Staff shortages, deficient knowledge, inappropriate attitudes, demanding workloads, analgesic shortages, and low prioritization of pain management have been identified in earlier studies as the nursing-related barriers to optimal children's pain management. These studies have mainly been undertaken in developed countr...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2020/7125060
更新日期:2020-01-20 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Few studies have examined the relationship between disability and borderline personality symptomatology, and, among those that have, findings have been inconsistent. In the present study, the relationship between medical disability and borderline personality symptomatology was examined in a sam...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2010/952816
更新日期:2010-11-01 00:00:00
abstract:Background:Despite the large body of research on sex differences in pain, there is a lack of knowledge about the influence of gender in the patient-provider encounter. The purpose of this study was to review literature on gendered norms about men and women with pain and gender bias in the treatment of pain. The second ...
journal_title:Pain research & management
pub_type: 杂志文章,评审
doi:10.1155/2018/6358624
更新日期:2018-02-25 00:00:00
abstract:Objective:To explore the effect of "selecting acupoints by site" on the synergy effect of "acupoint compatibility" according to the clinical efficacy of acupuncture treatment of patients with gastroparesis. Methods:A total of 99 patients who met the diagnostic criteria for gastroparesis were enrolled in 3 clinical cen...
journal_title:Pain research & management
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1155/2020/8751958
更新日期:2020-04-25 00:00:00
abstract:BACKGROUND:Leptin, an adipocyte-produced cytokine, interacts with various hormones, including those of the hypothalamic-pituitary-adrenal axis. Fibromyalgia is a syndrome characterized by widespread pain accompanied by tenderness. The pathogenesis involves a disturbance in pain processing and transmission by the centra...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2012/350654
更新日期:2012-03-01 00:00:00
abstract:Objectives:Dexmedetomidine is widely used as an adjunct to general anesthesia. In this study, we evaluated the effects of perioperative dexmedetomidine infusion on postoperative analgesia in patients undergoing lateral thoracotomy for thoracic esophageal cancer. Methods:A total of 62 patients undergoing lateral thorac...
journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
doi:10.1155/2020/4145893
更新日期:2020-05-06 00:00:00
abstract::There is limited evidence to underpin the assessment and management of pain in children with profound cognitive impairment and these children are vulnerable to poor pain assessment and management. Health professionals working with children with profound cognitive impairment from a single paediatric tertiary referral c...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2016/8617182
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Increasing attention is being devoted to cognitive-behavioural measures to improve interventions for chronic pain. OBJECTIVE:To develop an Italian version of the Coping Strategies Questionnaire - Revised (CSQ-R), and to validate it in a study involving 345 Italian subjects with chronic pain. METHODS:The qu...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2014/956828
更新日期:2014-05-01 00:00:00
abstract::The purpose of the present article was to assess the available literature concerning pain and autism. First, authors summarized the published articles on pain reactivity in people with autism. Second, the hypotheses envisaged to explain the presence of expressive particularities in people with autism spectrum disorder...
journal_title:Pain research & management
pub_type: 杂志文章,评审
doi:10.1155/2010/749275
更新日期:2010-07-01 00:00:00