Abstract：
:When underlying distributions are unknown and sample sizes are small, permutation tests may have superior features to parametric tests, such as smaller type I error and more accurate probability values when testing the null hypothesis. However, permutation tests are not widely used in clinical trials because of their computational complexity. We developed an efficient SAS macro to generate all possible permutations of the data and to run subsequent permutation tests of difference between means for two independent samples. The macro performs permutation tests and provides the exact probability of significance for a wide range of statistics, including geometric means, medians, mid-ranges, mean-ranks, proportions and variances to meet the needs of data analysis in clinical trials.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Balasubramani GK,Wisniewski SR,Zhang H,Eng HFdoi
10.1016/j.cmpb.2005.03.010subject
Has Abstractpub_date
2005-08-01 00:00:00pages
179-87issue
2eissn
0169-2607issn
1872-7565pii
S0169-2607(05)00084-2journal_volume
79pub_type
杂志文章abstract：BACKGROUND AND OBJECTIVE:Early detection of cardiovascular (CV) disease or associated risk factors during childhood is of paramount importance, allowing for early treatment or lifestyle modifications, respectively. The objective of this study was to describe the development of an electronic health record (EHR), with in...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2018.03.009
更新日期：2018-06-01 00:00:00
abstract：:The very first step for keeping good dental hygiene is to employ the correct toothbrushing style. Due to the possible occurrence of periodontal disease at an early age, it is critical to begin correct toothbrushing patterns as early as possible. With this aim, we proposed a novel toothbrush monitoring and training sys...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2009.04.006
更新日期：2009-11-01 00:00:00
abstract：:Fall detection, gait analysis and context recognition are examples of applications where capacitive accelerometers are widely used in health care. In most of the existing work, algorithms were developed for a specific platform and accelerometers were used without explicitly choosing a specific type. With this work we ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2011.10.009
更新日期：2012-05-01 00:00:00
abstract：OBJECTIVES:Postoperative delirium is a common complication after major surgery among the elderly. Despite its potentially serious consequences, the complication often goes undetected and undiagnosed. In order to provide diagnosis support one could potentially exploit the information hidden in free text documents from e...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.09.014
更新日期：2017-12-01 00:00:00
abstract：:Telemedicine provides a new way of delivering medical services. The good quality of the picture is, however, essential for a proper and reliable teleconsultation, especially in the cases when visual information about the patient's physical condition is of great importance as in ophthalmology and dermatology. Therefore...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(00)00120-6
更新日期：2001-05-01 00:00:00
abstract：:For the first time compressed sampling (CS) has been applied to heart rate (HR) measurements. The signals can be reconstructed from samples far below the Nyquist rate with negligible small errors, a sampling reduction of 8 has been demonstrated in the paper. As a result, the bitrate of the CS sampler is half when comp...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2012.06.002
更新日期：2012-12-01 00:00:00
abstract：:Open hashing is used to demonstrate the effectiveness of several hashing functions for the uniform distribution of biological records. The three types of database tested include (1) genetic nomenclature, mutation sites and strain names, (2) surnames extracted from literature files and (3) a set of 1000 numeric ASCII s...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(89)90164-8
更新日期：1989-02-01 00:00:00
abstract：:Closed-loop insulin delivery systems often implement glucose measurement and insulin administration in the subcutis. However some existing models for glucose-insulin system ignored the dynamics of subcutaneous glucose and subcutaneously-injected insulin. This paper reports a two-compartment model that includes glucose...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2013.05.001
更新日期：2013-08-01 00:00:00
abstract：:In the human body, the relation between fat and fat-free mass (muscles, bones etc.) is necessary for the diagnosis of obesity and prediction of its comorbidities. Numerous formulas, such as Deurenberg et al., Gallagher et al., Jackson and Pollock, Jackson et al. etc., are available to predict body fat percentage (BF%)...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2013.10.013
更新日期：2014-02-01 00:00:00
abstract：:metrumrg is an R package that facilitates workflow for the discipline of pharmacometrics. Support is provided for data preparation, modeling, simulation, diagnostics, and reporting. Existing tools and techniques are emphasized where available; original solutions are provided for otherwise unmet needs. In particular, m...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2012.08.009
更新日期：2013-01-01 00:00:00
abstract：:This paper summarizes the main topics of discussion at a workshop hosted by the Centre for Law Ethics and Risk in Telemedicine at the 2nd International Conference on Advances in the Delivery of Care, held at the Institute of Health Sciences, City University, London from Wednesday 24 to Friday 26 March 1999. The worksh...
journal_title：Computer methods and programs in biomedicine
pub_type：
doi：10.1016/s0169-2607(00)00142-5
更新日期：2001-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The primary objective of present analysis is to model the peristalsis of copper-water based nanoliquid in the presence of first order velocity and thermal slip conditions in a curved channel. Mixed convection, viscous dissipation and heat generation/absorption are also accounted. METHOD:Mathem...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.02.006
更新日期：2017-04-01 00:00:00
abstract：:A confocal microscope can produce gray-scale images of the different layers of the cornea. We have addressed the problem of classifying these images, i.e. recognizing the layer displayed, using the shape of the cells contained, which is uniquely related to each specific layer. A first method was designed, based first ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(01)00153-5
更新日期：2002-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Hepatocellular ballooning is an important histological parameter in the diagnosis of nonalcoholic steatohepatitis (NASH), and it is considered to be a morphological pattern that indicates the severity and the progression to cirrhosis and liver-related deaths. There remains uncertainty about the...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105614
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The presence of circulating tumor cells in the patient's blood is a clinical factor that indicates the initiation of metastasis. METHODS:In this paper, a microfluidic device is designed to separate, enumerate, and to diagnose cancer cells from the patient's blood sample. Here, we present a new...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105147
更新日期：2020-03-01 00:00:00
abstract：:Alzheimer's Disease (AD) is one of the leading causes of death in developed countries. From a research point of view, impressive results have been reported using computer-aided algorithms, but clinically no practical diagnostic method is available. In recent years, deep models have become popular, especially in dealin...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105242
更新日期：2020-04-01 00:00:00
abstract：:The increasing use of computer systems for storing patient information in different hospitals, in different departments within the same hospital, in clinics and even in doctors' surgeries, is creating a problem in terms of the fragmentation of the patient record. The lack of any coordination or standardization in the ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(94)90080-9
更新日期：1994-06-01 00:00:00
abstract：PURPOSE:develop and validate a PET sorting algorithm based on the respiratory amplitude to correct for abnormal respiratory cycles. METHOD AND MATERIALS:using the 4D NCAT phantom model, 3D PET images were simulated in lung and other structures at different times within a respiratory cycle and noise was added. To valid...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2007.05.004
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The anatomical structure detection in retinal images is an open problem. However, most of the works in the related literature are oriented to the detection of each structure individually or assume the previous detection of a structure which is used as a reference. The objective of this paper is...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.06.022
更新日期：2017-10-01 00:00:00
abstract：:In recent years, mild cognitive impairment (MCI) has attracted significant attention as an indicator of high risk for Alzheimer's disease (AD), and the diagnosis of MCI can alert patient to carry out appropriate strategies to prevent AD. To avoid subjectivity in diagnosis, we propose an ontology driven decision suppor...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2013.12.023
更新日期：2014-03-01 00:00:00
abstract：:Multicenter clinical trials usually involve several hundred research variables with tens of thousands of records and require mainframe computers for processing. Because of recent advances in hardware and software, it has become possible to support data management and statistical analysis for a complex research project...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(89)90094-1
更新日期：1989-12-01 00:00:00
abstract：:Endoscopy is used for inspection of the inner surface of organs such as the colon. During endoscopic inspection of the colon or colonoscopy, a tiny video camera generates a video signal, which is displayed on a monitor for interpretation in real-time by physicians. In practice, these images are not typically captured,...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2011.04.003
更新日期：2012-11-01 00:00:00
abstract：:We have implemented an interactive digital filter design program in the HP 1000 computer at the Department of Electrical Engineering of the University of Washington. This program allows users to design different types of filters interactively with both amplitude and phase responses displayed on graphic devices. The pe...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(85)90058-6
更新日期：1985-10-01 00:00:00
abstract：:This study employs the concept of applying constant-phase models to input respiratory impedance data obtained with the non-invasive Forced Oscillation Technique (FOT) lung function test. Changes in respiratory mechanics from healthy and chronic obstructive pulmonary disease (COPD) diagnosed patients are observed with ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2009.06.006
更新日期：2010-01-01 00:00:00
abstract：:NONMEM is an extremely powerful tool for nonlinear mixed-effect modelling and simulation of pharmacokinetic and pharmacodynamic data. However, it is a console-based application whose output does not lend itself to rapid interpretation or efficient management. NONMEMory has been created to be a comprehensive project ma...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2005.02.003
更新日期：2005-06-01 00:00:00
abstract：:Methods for evaluating a single diagnostic test with reference to the disease prevalence in a given population include sensitivity, specificity, positive predictive value, negative predictive value, and accuracy. Patient disease status and, ultimately, the treatment course is determined by the outcome of these diagnos...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(91)90119-e
更新日期：1991-07-01 00:00:00
abstract：:This article presents a method of predictive simulation, patient-dependant, in real time of the abdominal organ positions during free breathing. The method, that considers both influence of the abdominal breathing and thoracic breathing, needs a tracking of the patient skin and a model of the patient-specific modifica...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2010.03.003
更新日期：2010-11-01 00:00:00
abstract：:This paper describes the results of a controlled multicenter study on the effect of the computer assistance in the intensive insulin therapy. The patient collective consisted of 50 diabetics, randomly divided in two groups with 25 patients per group. The Multiple Subcutaneous Injection (MSI) group was treated with the...
journal_title：Computer methods and programs in biomedicine
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0169-2607(02)00034-2
更新日期：2002-08-01 00:00:00
abstract：:This corrigendum corrects the dimensions of partial differential equations in the paper [1], where these mistakes are occurred during typing processes. But the results in [1] does not affect the scientific and mathematical validity of the paper. ...
journal_title：Computer methods and programs in biomedicine
pub_type： 信件
doi：10.1016/j.cmpb.2019.105251
更新日期：2020-04-01 00:00:00
abstract：:The aim of DILEMMA is to provide tools for the development of decision support systems for use in general medical practice, hospital-based cancer care, and shared care of cancer and cardiology patients. In primary care, the project intends to provide aids to clinical performance in prescribing, referral and the use of...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(94)90011-6
更新日期：1994-10-01 00:00:00
