Abstract:
:The aim of DILEMMA is to provide tools for the development of decision support systems for use in general medical practice, hospital-based cancer care, and shared care of cancer and cardiology patients. In primary care, the project intends to provide aids to clinical performance in prescribing, referral and the use of clinical guidelines. The demonstrator applications involve telematics and knowledge-based methodology, using an approach termed logic engineering which combines logic programming and software lifecycle methods. DILEMMA will demonstrate systems to assist shared care and home care which should help reduce pressure on secondary health resources and, by disseminating best practice knowledge, improve patient care and patient quality of life.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Gordon C,Jackson-Smale A,Thomson Rdoi
10.1016/0169-2607(94)90011-6subject
Has Abstractpub_date
1994-10-01 00:00:00pages
37-9issue
1-2eissn
0169-2607issn
1872-7565pii
0169-2607(94)90011-6journal_volume
45pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVE:Segmentation is a crucial step in multiple biomechanics and orthopedics applications. The time-intensiveness and expertise requirements of medical image segmentation present a significant bottleneck for corresponding workflows. The current study develops and evaluates convolutional neural netwo...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105328
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Social Network Analysis is an attractive approach to model and analyze complex networks. In recent years, several bioinformatics related networks have been modeled and analyzed thoroughly using social network analysis. The objective of this study is to build a social network analysis based cla...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2017.06.015
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Although analytical models have been used to quickly predict head response under impact condition, the existing models generally took the head as regular shell with uniform thickness which cannot account for the actual head geometry with varied cranial thickness and curvature at different locat...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2018.04.022
更新日期:2018-07-01 00:00:00
abstract::How to distinguish 1 billion individuals by an identifier consisting of eight characters, allowing a reasonable amount of error detection or even error correction? Our solution of this problem is an optimal code over a 32-character alphabet that detects up to two errors and corrects one error as well as a transpositio...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2005.03.004
更新日期:2005-07-01 00:00:00
abstract::Characterization of carotid atherosclerosis and classification into either symptomatic or asymptomatic is crucial in terms of diagnosis and treatment planning for a range of cardiovascular diseases. This paper presents a computer-aided diagnosis (CAD) system (Atheromatic) that analyzes ultrasound images and classifies...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2012.09.008
更新日期:2013-04-01 00:00:00
abstract::DIMSUM, an acronym for DIMension of a SUM of exponentials, is a highly automated expert system for fitting multiexponential models of increasing dimension to time series data. Up to now, a researcher has needed an individual copy of DIMSUM on his or her own computer as well as support to learn how to use it. W3DIMSUM,...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2005.03.008
更新日期:2005-08-01 00:00:00
abstract::Elderly people are commonly affected by Parkinson's disease (PD) which is one of the most common neurodegenerative disorders due to the loss of dopamine-producing brain cells. People with PD's (PWP) may have difficulty in walking, talking or completing other simple tasks. Variety of medications is available to treat P...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2014.01.004
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Prostate segmentation on Magnetic Resonance (MR) imaging is problematic because disease changes the shape and boundaries of the gland and it can be difficult to separate the prostate from surrounding tissues. We propose an automated model that extracts and combines multi-level features in a dee...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2018.12.031
更新日期:2019-03-01 00:00:00
abstract::A linear time invariant model is applied to functional fMRI blood flow data. Based on traditional time series analysis, this model assumes that the fMRI stochastic output sequence can be determined by a constant plus a linear filter (hemodynamic response function) of several fixed deterministic inputs and an error ter...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2005.12.003
更新日期:2006-04-01 00:00:00
abstract::Lumped parameter approaches for modelling the cardiovascular system typically have many parameters of which a significant percentage are often not identifiable from limited data sets. Hence, significant parts of the model are required to be simulated with little overall effect on the accuracy of data fitting, as well ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2010.01.002
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:The augmentation of cooling or heating in a mechanical and industrial process may create a saving in energy, decrease process time, protract the working existence of hardware and raise thermal rating. A few procedures are even influenced subjectively by the action of increased heat transport. The advancement...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.105017
更新日期:2019-10-01 00:00:00
abstract::We have developed a fast, user friendly, ray-tracing program, "CSIM" for low-energy gamma rays (up to ∼200keV) to simulate the performance characteristics of parallelhole collimators. We have used a ray-tracing approach to find the sensitivity and resolution of the parallelhole collimator by including the penetration ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2012.12.004
更新日期:2013-06-01 00:00:00
abstract::A novel approach for the heartbeat and respiration detection based on optical interferometer and wavelet transform is proposed in this paper. Optical interferometer is a sensitive device that detects physical elongation of optical fibre due to external perturbations. Mechanical activity of cardiac muscle and respirati...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2013.03.003
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:Assessing prognosis for acetaminophen-induced acute liver failure (APAP-ALF) patients during the first week of hospitalization often presents significant challenges. Current models such as the King's College Criteria (KCC) and the Acute Liver Failure Study Group (ALFSG) Prognostic Index are develop...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.04.012
更新日期:2019-07-01 00:00:00
abstract::This paper describes the open source framework MARVIN for rapid application development in the field of biomedical and clinical research. MARVIN applications consist of modules that can be plugged together in order to provide the functionality required for a specific experimental scenario. Application modules work on ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2008.04.007
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Anxiety is one of the major influences on the dropout of relapse and treatment of substance abuse treatment. Chemically dependent individuals need (CDI) to be aware of their emotional state in situations of risk during their treatment. Many patients do not agree with the diagnosis of the therap...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2016.11.014
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Finite element based simulation has emerged as a powerful tool to analyse the tooth strength and its fracture characteristics. The aim of this study is to compare and evaluate the fracture resistance of immature teeth reinforcement with MTA, Biodentine and Bioaggregate as an apical plug and bac...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105356
更新日期:2020-07-01 00:00:00
abstract::A minimal model of the cardio-vascular system (CVS) with ventricular interaction and inertial effects that accurately captures the physiological trends of a variety of disease states has been developed. However, the physiologically accurate open on pressure, close on flow valve law is computationally heavy to implemen...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2005.06.003
更新日期:2005-10-01 00:00:00
abstract::Articular cartilage (AC) is a biological tissue that allows the distribution of mechanical loads and movement of joints. The presence of these mechanical loads influences the behavior and physiological condition of AC. The loads may cause damaged by fatigue through injuries due to repeated accumulated stresses. The ai...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2011.02.003
更新日期:2011-12-01 00:00:00
abstract::This paper describes a distributed collaborative effort between industry and academia to systematize data management in an academic biomedical laboratory. Heterogeneous and voluminous nature of research data created in biomedical laboratories make information management difficult and research unproductive. One such co...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2015.11.001
更新日期:2016-04-01 00:00:00
abstract::In muscle cells, force development is controlled by Ca2+ ions, which are rapidly released from the sarcoplasmic reticulum (SR) during sarcolemmal depolarization. In addition to this synchronized spatially homogeneous calcium signal, localized quantal Ca2+ release events (sparks) have been recorded using laser scanning...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2004.06.004
更新日期:2005-01-01 00:00:00
abstract::This article presents a method of predictive simulation, patient-dependant, in real time of the abdominal organ positions during free breathing. The method, that considers both influence of the abdominal breathing and thoracic breathing, needs a tracking of the patient skin and a model of the patient-specific modifica...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2010.03.003
更新日期:2010-11-01 00:00:00
abstract::Magnetic resonance angiography (MRA) offers a non-invasive approach to the acquisition of anatomically accurate human arterial structure. Combining the latest computational fluid dynamics (CFD) techniques with clinical data from MRA, the detailed haemodynamics information in the human circulation system can be obtaine...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(98)00008-x
更新日期:1998-06-01 00:00:00
abstract::Cone beam computed tomography (CBCT) enables volumetric image reconstruction from 2D projection data and plays an important role in image guided radiation therapy (IGRT). Filtered back projection is still the most frequently used algorithm in applications. The algorithm discretizes the scanning process (forward projec...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2011.12.002
更新日期:2012-11-01 00:00:00
abstract::The goal of our study is to develop a fast parallel implementation of group independent component analysis (ICA) for functional magnetic resonance imaging (fMRI) data using graphics processing units (GPU). Though ICA has become a standard method to identify brain functional connectivity of the fMRI data, it is computa...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2015.02.002
更新日期:2015-04-01 00:00:00
abstract::The assessment of sample size in clinical trials comparing means requires a variance estimate of the main efficacy variable. If no reliable information about the variance of the key response is available at the beginning of a clinical trial, the use of data from the first 'few' patients entered in the trial ('internal...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(00)00119-x
更新日期:2001-06-01 00:00:00
abstract::We discuss how vocal disorders can be post-corrected via a simple nonlinear noise reduction scheme. This work is motivated by the need of a better understanding of voice dysfunctions. This would entail a 2-fold advantage for affected patients: Physicians can perform better surgical interventions and on the other hand ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(01)00161-4
更新日期:2002-05-01 00:00:00
abstract::When underlying distributions are unknown and sample sizes are small, permutation tests may have superior features to parametric tests, such as smaller type I error and more accurate probability values when testing the null hypothesis. However, permutation tests are not widely used in clinical trials because of their ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2005.03.010
更新日期:2005-08-01 00:00:00
abstract::Methods for evaluating a single diagnostic test with reference to the disease prevalence in a given population include sensitivity, specificity, positive predictive value, negative predictive value, and accuracy. Patient disease status and, ultimately, the treatment course is determined by the outcome of these diagnos...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(91)90119-e
更新日期:1991-07-01 00:00:00
abstract::This study presents the development of a hybrid system consisting of an ensemble of Extended Kalman Filter (EKF) based Multi Layer Perceptron Network (MLPN) and a one-pass learning Fuzzy Inference System using Look-up Table Scheme for the recognition of electrocardiogram (ECG) signals. This system can distinguish vari...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2006.03.003
更新日期:2006-05-01 00:00:00