Abstract:
BACKGROUND AND OBJECTIVE:Anxiety is one of the major influences on the dropout of relapse and treatment of substance abuse treatment. Chemically dependent individuals need (CDI) to be aware of their emotional state in situations of risk during their treatment. Many patients do not agree with the diagnosis of the therapist when considering them vulnerable to environmental stimuli related to drugs. This research presents a cue reactivity detection tool based on a device acquiring physiological signals connected to personal computer. Depending on the variations of the emotional state of the drug addict, alteration of the physiological signals will be detected by the computer tool (CT) which will modify the displayed virtual sets without intervention of the therapist. METHODS:Developed in 3ds Max® software, the CT is composed of scenarios and objects that are in the habit of marijuana and cocaine dependent individual's daily life. The interaction with the environment is accomplished using a Human-Computer Interface (HCI) that converts incoming physiological signals indicating anxiety state into commands that change the scenes. Anxiety was characterized by the average variability from cardiac and respiratory rate of 30 volunteers submitted stress environment situations. To evaluate the effectiveness of cue reactivity a total of 50 volunteers who were marijuana, cocaine or both dependent were accompanied. RESULTS:Prior to CT, the results demonstrated a poor correlation between the therapists' predictions and those of the chemically dependent individuals. After exposure to the CT, there was a significant increase of 73% in awareness of the risks of relapse. CONCLUSION:We confirmed the hypothesis that the CT, controlled only by physiological signals, increases the perception of vulnerability to risk situations of individuals with dependence on marijuana, cocaine or both.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Silva MLD,Frère AF,Oliveira HJQ,Martucci Neto H,Scardovelli TAdoi
10.1016/j.cmpb.2016.11.014subject
Has Abstractpub_date
2017-03-01 00:00:00pages
139-149eissn
0169-2607issn
1872-7565pii
S0169-2607(16)30112-2journal_volume
140pub_type
杂志文章abstract::In this paper we discuss the SIMID tool for simulation of the spread of infectious disease, enabling spatio-temporal visualization of the dynamics of influenza outbreaks. SIMID is based on modern random network methodology and implemented within the R and GIS frameworks. The key advantage of SIMID is that it allows no...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2013.01.007
更新日期:2013-06-01 00:00:00
abstract::Glucose-insulin system models are commonly used for identifying insulin sensitivity. With physiological, 2-compartment insulin kinetics models, accurate kinetic parameter values are required for reliable estimates of insulin sensitivity. This study uses data from 6 published microdialysis studies to determine the most...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2014.01.011
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Standardization of the carotid IMT requires a reference marker in ultrasound scans. It has been shown previously that manual reference marker and manually created carotid segments are used for measuring IMT in these segments. Manual methods are tedious, time consuming, subjective, and prone to...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2017.01.009
更新日期:2017-04-01 00:00:00
abstract::Several approaches, based on different assumptions and with various degree of theoretical sophistication and implementation complexity, have been developed for improving the measurement of evoked potentials (EP) performed by conventional averaging (CA). In many of these methods, one of the major challenges is the expl...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(01)00175-4
更新日期:2002-06-01 00:00:00
abstract::A set of programs is described by which a consistent morphometry of bone sections can be performed. The programs are written in FORTRAN IV in a PDP 11/10 minicomputer, under the RT-11 operating system. The bone sections are run through the field of vision of the microscope using a scanning stage in one of several pres...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(85)90003-3
更新日期:1985-12-01 00:00:00
abstract:BACKGROUND:The low (LF) vs. high (HF) frequency energy ratio, computed from the spectral decomposition of heart beat intervals, has become a major tool in cardiac autonomic system control and sympatho-vagal balance studies. The (statistical) distributions of response variables designed from ratios of two quantities, su...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2009.11.001
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Finite element based simulation has emerged as a powerful tool to analyse the tooth strength and its fracture characteristics. The aim of this study is to compare and evaluate the fracture resistance of immature teeth reinforcement with MTA, Biodentine and Bioaggregate as an apical plug and bac...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105356
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To observe the efficacy of distal tibial tuberosity high tibial osteotomy in treating medial compartment osteoarthritis of the knee. In the experiment, a medical image enhancement algorithm based on shear wave domain improved Gamma correction was implemented to process medical images in order to diagnose pati...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105349
更新日期:2020-07-01 00:00:00
abstract::Arterial bypass grafts tend to fail after some years due to the development of intimal thickening (restenosis). Non-uniform hemodynamics following a bypass operation contributes to restenosis and bypass failure can occur due to the focal development of anastomotic intimal hyperplasia. Additionally, surgical injury agg...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章,评审
doi:10.1016/j.cmpb.2011.12.005
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In the last decade, RNA-sequencing technology has become method-of-choice and prefered to microarray technology for gene expression based classification and differential expression analysis since it produces less noisy data. Although there are many algorithms proposed for microarray data, the n...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.04.007
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Capturing the context of text is a challenging task in biomedical text summarization. The objective of this research is to show how contextualized embeddings produced by a deep bidirectional language model can be utilized to quantify the informative content of sentences in biomedical text summa...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.105117
更新日期:2020-02-01 00:00:00
abstract::Cardiac MR image-based predictive models integrating statistical atlases of heart anatomy and fiber orientations can aid in better diagnosis of cardiovascular disease, a major cause of death worldwide. Such atlases have been built from diffusion tensor (DT) images and can be used in anisotropic models for personalized...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.105200
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:With ongoing interest in CNT nanofluids and materials in biotechnology, energy and environment, microelectronics, composite materials etc., the current investigation is carried out to analyze the effects of variable viscosity and thermal conductivity of CNT nanofluids flow driven by cilia indu...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2016.08.001
更新日期:2016-11-01 00:00:00
abstract::A cardiovascular system model and parameter identification method have previously been validated for porcine experiments of induced pulmonary embolism and positive end-expiratory pressure (PEEP) titrations, accurately tracking all the main hemodynamic trends. In this research, the model and parameter identification pr...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2008.03.004
更新日期:2008-08-01 00:00:00
abstract::Endoscopy is used for inspection of the inner surface of organs such as the colon. During endoscopic inspection of the colon or colonoscopy, a tiny video camera generates a video signal, which is displayed on a monitor for interpretation in real-time by physicians. In practice, these images are not typically captured,...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2011.04.003
更新日期:2012-11-01 00:00:00
abstract::The role of repetitive firing in neurophysiologic or neuropsychiatric disorders, such as Parkinson, epilepsy and bipolar type disorders, has always been a topic of medical research as therapies target either the cease of firing or a decrease in its frequency. In electrotherapy, one of the mechanisms to achieve the pur...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2010.01.006
更新日期:2010-07-01 00:00:00
abstract::We propose a fast seed detection for automatic tracking of coronary arteries in coronary computed tomographic angiography (CCTA). To detect vessel regions, Hessian-based filtering is combined with a new local geometric feature that is based on the similarity of the consecutive cross-sections perpendicular to the vesse...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2014.07.005
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In recent years, many attempts have been made to design reliable systems for identifying individuals using biometrics. Electrocardiogram (ECG) biometric is one of the newest methods that not only offers unique characteristics of individuals for human identification, but also the possibility of ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.02.009
更新日期:2019-04-01 00:00:00
abstract::This paper compares bibliographic retrieval using current MeSH (Medical Subject Headings) to bibliographic retrieval using explicitly coded semantic relationships between index terms. In a previous study, ten lists of abstracts, each list containing 20-40 papers discussing a specific pair of terms, were analyzed to id...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(88)90084-3
更新日期:1988-11-01 00:00:00
abstract::The mixture cure model is a special type of survival models and it assumes that the studied population is a mixture of susceptible individuals who may experience the event of interest, and cure/non-susceptible individuals who will never experience the event. For such data, standard survival models are usually not appr...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2012.08.013
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Cartilage cracks and fissures may occur due to certain daily life activities such as sports practice, blunt trauma, and matrix fibrillation during early osteoarthritis. These cracks could further grow at the macroscopic level, alter the load distribution pattern in the matrix, limit the joint r...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105648
更新日期:2020-10-01 00:00:00
abstract::Traditional gait and fluoroscopy analysis of human movement are largely utilised but are still limited in registration, integration, synchronisation and visualisation capabilities. The present work exploits the features of a recently developed software tool based on multimodal display (Data Manager developed within th...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2005.04.007
更新日期:2005-09-01 00:00:00
abstract::This paper describes the open source framework MARVIN for rapid application development in the field of biomedical and clinical research. MARVIN applications consist of modules that can be plugged together in order to provide the functionality required for a specific experimental scenario. Application modules work on ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2008.04.007
更新日期:2008-08-01 00:00:00
abstract::A great challenge in osteoporosis clinical assessment is identifying patients at higher risk of hip fracture. Bone Mineral Density (BMD) measured by Dual-Energy X-Ray Absorptiometry (DXA) is the current gold-standard, but its classification accuracy is limited to 65%. DXA-based Finite Element (FE) models have been dev...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105484
更新日期:2020-09-01 00:00:00
abstract::An interactive Pascal program for use in the IBM-PC and compatible computers is presented. It simulates the activation of integral membrane proteins involved in ionic transport. The program allows variation of the number of transport proteins, ionic concentrations, permeability ratios, voltage dependence of permeabili...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(89)90089-8
更新日期:1989-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Model-based lung mechanics monitoring can provide clinically useful information for guiding mechanical ventilator treatment in intensive care. However, many methods of measuring lung mechanics are not appropriate for both fully and partially sedated patients, and are unable provide lung mechani...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.105184
更新日期:2020-04-01 00:00:00
abstract::Radiologic and clinical practice can be enhanced by improved access to multimodal image information. Analysis, visualization, method characteristic image processing and image synthesis is needed not only for the interpretation of the images but also for performing effective consultations with clinical colleagues and c...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(94)90070-1
更新日期:1994-06-01 00:00:00
abstract::The aim of this study was to examine the accuracy of the computerized 3D surface analyzing and volume measuring method in dentistry. Two different types of test objects were used in the first part of the measurements. Each sample of the two groups was cross-sectioned using a hard tissue microtome. The sections were ph...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(00)00059-6
更新日期:2000-10-01 00:00:00
abstract::The use of well characterized laboratory animals in biomedical research is of importance for quality securing and reproducibility of animal experiments. Therefore, breeders should not only have in mind the reproduction of their animal stocks, but they should also be interested to achieve an optimal resemblance of the ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(92)90076-j
更新日期:1992-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Glaucoma, a worldwide eye disease, may cause irreversible vision damage. If not treated properly at an early stage, glaucoma eventually deteriorates into blindness. Various glaucoma screening methods, e.g. Ultrasound Biomicroscopy (UBM), Optical Coherence Tomography (OCT), and Heidelberg Retina...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105717
更新日期:2020-12-01 00:00:00