Abstract：
:An interactive Pascal program for use in the IBM-PC and compatible computers is presented. It simulates the activation of integral membrane proteins involved in ionic transport. The program allows variation of the number of transport proteins, ionic concentrations, permeability ratios, voltage dependence of permeabilities and temperature. A separate procedure for simulation of Na+-K+ pumps has been included considering their relevance in physiology. The main purpose of the present program is to serve as a teaching aid to understand the basic principles and concepts related with the electrogenesis and the stoichiometry of membrane transport processes.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Holmgren M,Diez-Martínez Odoi
10.1016/0169-2607(89)90089-8subject
Has Abstractpub_date
1989-05-01 00:00:00pages
43-50issue
1eissn
0169-2607issn
1872-7565pii
0169-2607(89)90089-8journal_volume
29pub_type
杂志文章abstract：:In cardiology, ultrasound is often used to diagnose heart disease associated with myocardial infarction. This study aims to develop robust segmentation techniques for segmenting the left ventricle (LV) in ultrasound images to check myocardium movement during heartbeat. The proposed technique utilizes machine learning ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105914
更新日期：2020-12-17 00:00:00
abstract：:This work is aimed at developing an innovative simulation environment supporting and improving the design of standard joint implants (JPD integrated design environment (JIDE)). The conceptual workflow starts from the design of a new implant, by using conventional CAD programmes and completes with the generation of a r...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2001.12.001
更新日期：2004-09-01 00:00:00
abstract：:We propose a fast seed detection for automatic tracking of coronary arteries in coronary computed tomographic angiography (CCTA). To detect vessel regions, Hessian-based filtering is combined with a new local geometric feature that is based on the similarity of the consecutive cross-sections perpendicular to the vesse...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2014.07.005
更新日期：2014-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:A new expert system is proposed to discriminate healthy people from people with Parkinson's Disease (PD) in early stages by using Diadochokinesis tests. METHODS:The system is based on temporal and spectral features extracted from the Voice Onset Time (VOT) segments of /ka/ syllables, whose bou...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.11.010
更新日期：2018-02-01 00:00:00
abstract：:Role of hepatic insulin degradation in modulating insulin delivery to peripheral circulation, in insulin-resistant hypertensive patients, is not yet fully understood. This issue was investigated here by a novel application to hypertension of a previously proposed minimal modelling of insulin and C-peptide data, using ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2009.08.007
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:In most countries, the higher death rates are due to cardiovascular disease and stroke. These problems often derive from irregular blood flow and the circulatory system disorder. METHODS:In this paper, the blood flow is simulated in a created aneurysm in the artery upon using Lattice Boltzmann...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105312
更新日期：2020-04-01 00:00:00
abstract：:Workplace description is an operation indispensable for the identification of professional risks and, in fulfillment of that objective, can best be accomplished by listing the constituent tasks associated with each job. This article presents a software in Visual-Basic to be run on a portable micro-computer, which faci...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(97)01777-x
更新日期：1997-01-01 00:00:00
abstract：:Gaze is a natural input for a Human Computer Interface (HCI) for disabled people, who have of course an acute need for a communication system. An efficient eye tracking procedure is presented providing a non-invasive method for real time detection of a subject eyes in a sequence of frames captured by low cost equipmen...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2009.03.010
更新日期：2009-10-01 00:00:00
abstract：:Karyotype analysis is a widespread procedure in cytogenetics to assess the presence of genetic defects by the visualization of the structure of chromosomes. The procedure is lengthy and repetitive and an effective automatic analysis would greatly help the cytogeneticist routine work. Still, automatic segmentation and ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章,评审
doi：10.1016/j.cmpb.2011.12.003
更新日期：2012-11-01 00:00:00
abstract：:Digital tomosynthesis is a method of limited angle reconstruction of tomographic images produced at variable heights, on the basis of a set of angular projections taken in an arc around human anatomy. Reconstructed tomograms from unprocessed original projection images, however, are invariably affected by tomographic n...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2011.09.013
更新日期：2012-07-01 00:00:00
abstract：:Over the past two decades, the use of telemedicine as a way to provide medical services has grown as communication technologies advance and patients seek more convenient ways to receive care. Because developments within this field are still rapidly evolving, identifying trends within telemedicine literature is an impo...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2015.09.008
更新日期：2015-12-01 00:00:00
abstract：:The Intensive Care Unit (ICU) is an extremely data-intensive environment where each patient needs to be monitored 24/7. Bedside monitors continuously register vital patient values (such as serum creatinine, systolic blood pressure) which are recorded frequently in the hospital database (e.g. every 2 min in the ICU of ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2010.03.019
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Cerebrovascular diseases (CVDs) affect a large number of patients and often have devastating outcomes. The hallmarks of CVDs are the abnormalities formed on brain blood vessels, including protrusions, narrows, widening, and bifurcation of the blood vessels. CVDs are often diagnosed by digital s...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105159
更新日期：2020-03-01 00:00:00
abstract：:Measurement systems used in the collection and processing of laboratory data must be calibrated periodically to obtain accurate results. Because calibration factors can change over time or may be reset to optimize measurements for specific tests, care must be taken to assure that calibration factors and data are align...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(91)90014-k
更新日期：1991-09-01 00:00:00
abstract：:The long-term variability of the fetal heart rate (FHR) provides valuable information on the fetal health status. The routine clinical FHR measurements are usually carried out by the means of ultrasound cardiography. Although the frequent FHR monitoring is recommendable, the high quality ultrasound devices are so expe...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(02)00111-6
更新日期：2003-07-01 00:00:00
abstract：:The assessment of sample size in clinical trials comparing means requires a variance estimate of the main efficacy variable. If no reliable information about the variance of the key response is available at the beginning of a clinical trial, the use of data from the first 'few' patients entered in the trial ('internal...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(00)00119-x
更新日期：2001-06-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:In the last decade, RNA-sequencing technology has become method-of-choice and prefered to microarray technology for gene expression based classification and differential expression analysis since it produces less noisy data. Although there are many algorithms proposed for microarray data, the n...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.04.007
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The anatomical structure detection in retinal images is an open problem. However, most of the works in the related literature are oriented to the detection of each structure individually or assume the previous detection of a structure which is used as a reference. The objective of this paper is...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.06.022
更新日期：2017-10-01 00:00:00
abstract：:Selecting appropriate ventilator settings decreases the risk of ventilator-induced lung injury. A decision support system (DSS) has been developed based on physiological models, which can advise on setting of tidal volume (Vt), respiratory frequency (f) and fraction of inspired oxygen (FiO2). The aim of this study is ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2008.07.001
更新日期：2008-11-01 00:00:00
abstract：BACKGROUND:Study of nanofluids has been enormously increased for the last couple of years. Regardless of some irregularity in the revealed outcomes and lacking consistency, yet the mechanisms of heat transport have been emerged as highly efficient. In the continuation of nanomaterials research, the investigators and an...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105093
更新日期：2020-01-01 00:00:00
abstract：:A highly optimized software for the kinetic analysis of complex chemical models is presented. The program is applied to the analysis of a vectorial biochemical reaction, where many species are linked by multiple equilibria of any order. The reaction stimulates the Ca2(+)-transport-linked ATPase reaction taking place i...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(90)90018-5
更新日期：1990-09-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Fraction of Inspired Oxygen is one of the arbitrary set ventilator parameters which has critical influence on the concentration of blood oxygen. Normally mechanical ventilators providing respiratory assistance are tuned manually to supply required inspired oxygen to keep the oxygen saturation a...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.04.014
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Virtual simulations recreate scenarios where student nurses can practice procedures in a safe and supervised manner and with no risk to the patient. Virtual scenarios include digital characters that reproduce human actions. Generally, these characters are modeled as males and restricted roles a...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2018.05.019
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Respiratory gating training is a common technique to increase patient proprioception, with the goal of (e.g.) minimizing the effects of organ motion during radiotherapy. In this work, we devise a system based on autoencoders for classification of regular, apnea and unconstrained breathing patte...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105675
更新日期：2020-10-01 00:00:00
abstract：:Tight glycemic control (TGC) has shown benefits in ICU patients, but been difficult to achieve consistently due to inter- and intra- patient variability that requires more adaptive, patient-specific solutions. STAR (Stochastic TARgeted) is a flexible model-based TGC framework accounting for patient variability with a ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2011.07.003
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Virtual reality surgery simulators have been proved effective for training in several surgical disciplines. Nevertheless, this technology is presently underutilized in orthopaedics, especially for bone machining procedures, due to the limited realism in haptic simulation of bone interactions. ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105263
更新日期：2020-05-01 00:00:00
abstract：:The need for flexible and well understood knowledge representations which are capable of capturing clinical guidelines and protocols for decision support systems is widely recognised. The PROforma method for specifying clinical guidelines and protocols comprises a graphical notation for their design, and a formal know...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(97)00034-5
更新日期：1997-09-01 00:00:00
abstract：:The aim of the present study was to design, implement and evaluate a software system for discriminating between metastatic and primary brain tumors (gliomas and meningiomas) on MRI, employing textural features from routinely taken T1 post-contrast images. The proposed classifier is a modified probabilistic neural netw...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2007.10.007
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Automated segmentation with high accuracy and speed is a prerequisite for FEA-based quantitative assessment with a large population. However, hip joint segmentation has remained challenging due to a narrow articular cartilage and thin cortical bone with a marked interindividual variance. To ove...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.11.007
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Attention deficit hyperactivity disorder (ADHD) is often presented with conduct disorder (CD). There is currently no objective laboratory test or diagnostic method to discern between ADHD and CD, and diagnosis is further made difficult as ADHD is a common neuro-developmental disorder often pre...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2021.105941
更新日期：2021-01-14 00:00:00
