Abstract：
BACKGROUND AND OBJECTIVE:Fraction of Inspired Oxygen is one of the arbitrary set ventilator parameters which has critical influence on the concentration of blood oxygen. Normally mechanical ventilators providing respiratory assistance are tuned manually to supply required inspired oxygen to keep the oxygen saturation at the desired level. Maintaining oxygen saturation in the desired limit is so vital since excess supply of inspired oxygen leads to hypercapnia and respiratory acidosis which lead to increased risk in cell damage and death. On the other side a sudden drop in oxygen saturation will lead to severe cardiac arrest and seizure. Hence intelligent real time control of blood oxygen level saturation is highly significant for patients in intensive care units. METHODS:This paper gives statistical pair wise analysis for finding out deeply correlated physiological parameters from clinical data for fixing fuzzy variables. An advisory fuzzy controller using Mamdani model is developed with R programming to predict FiO2 which is to be delivered from the ventilator to maintain SaO2 with in required levels. RESULTS:Fuzzy variables for the fuzzy model is fixed using 75% of the clinical data collected. Remaining 25% of the data is used for checking the system. Compared the predictive output of the system with physicians' decisions and found to be accurate with less than five percentage error. CONCLUSIONS:Based on the comparison the system is proved to be effective and can be used as assist mode for physicians for effective decision making.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Radhakrishnan S,Nair SG,Isaac Jdoi
10.1016/j.cmpb.2019.04.014subject
Has Abstractpub_date
2019-07-01 00:00:00pages
43-49eissn
0169-2607issn
1872-7565pii
S0169-2607(18)31783-8journal_volume
176pub_type
杂志文章abstract：BACKGROUND AND OBJECTIVE:Prostate segmentation on Magnetic Resonance (MR) imaging is problematic because disease changes the shape and boundaries of the gland and it can be difficult to separate the prostate from surrounding tissues. We propose an automated model that extracts and combines multi-level features in a dee...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2018.12.031
更新日期：2019-03-01 00:00:00
abstract：:The analysis of human motion from video has been the object of interest for many application areas, these including surveillance, control, biomedical analysis, video annotation etc. This paper addresses the advances within this topic in relation to epilepsy, a domain where human motion is with no doubt one of the most...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章,评审
doi：10.1016/j.cmpb.2012.08.005
更新日期：2012-12-01 00:00:00
abstract：:In this paper the model predictive control (MPC) technology is used for tackling the optimal drug administration problem. The important advantage of MPC compared to other control technologies is that it explicitly takes into account the constraints of the system. In particular, for drug treatments of living organisms,...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2014.06.003
更新日期：2014-10-01 00:00:00
abstract：:The aim of this study was to provide numerical evidence that latanoprost induced iris darkening (LIID) can be caused by changes to the melanin granule size distribution in the anterior segment of the iris. Iridectomies from two patients were used, where both had undergone unilateral treatment with latanoprost and had ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2007.04.010
更新日期：2007-08-01 00:00:00
abstract：:The impact of a problem based curriculum has been the subject of increasing interest, as evidenced by several recent articles on the subject [1-4]. McMaster was able to design its library to serve a problem-based curriculum, but since there had been no prior experience with such a curriculum, the library was designed ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(94)90110-4
更新日期：1994-09-01 00:00:00
abstract：:A computer program for a microcomputer (HP 86) is presented to discriminate between different models and to design new experiments for model discrimination. By a non-linear fitting algorithm a set of experimental data is fitted with different models suggested by the user. The parameters characterizing each model are e...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(86)90022-2
更新日期：1986-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Social Network Analysis is an attractive approach to model and analyze complex networks. In recent years, several bioinformatics related networks have been modeled and analyzed thoroughly using social network analysis. The objective of this study is to build a social network analysis based cla...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.06.015
更新日期：2017-10-01 00:00:00
abstract：:Vascular catheterization is a common procedure in clinical medicine. It is normally performed by a specialist using an X-ray fluoroscopic guide and contrast-media. In the present paper, an image-guided navigation system which indicates a path providing guidance to the desired target inside the vascular tree is describ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2007.07.009
更新日期：2007-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Dataset imbalance is an important problem in neuroimaging. Imbalanced datasets would cause the performance degradation of a classifier by utilizing imbalanced learning, which tends to overfocus on the majority class. In this paper, we consider an imbalanced neuroimaging classification problem, ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105676
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Deep learning enables tremendous progress in medical image analysis. One driving force of this progress are open-source frameworks like TensorFlow and PyTorch. However, these frameworks rarely address issues specific to the domain of medical image analysis, such as 3-D data handling and distanc...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105796
更新日期：2021-01-01 00:00:00
abstract：:Glucose-insulin system models are commonly used for identifying insulin sensitivity. With physiological, 2-compartment insulin kinetics models, accurate kinetic parameter values are required for reliable estimates of insulin sensitivity. This study uses data from 6 published microdialysis studies to determine the most...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2014.01.011
更新日期：2014-05-01 00:00:00
abstract：:We have designed and implemented a human brain multi-modality database system with content-based image management, navigation and retrieval support for epilepsy. The system consists of several modules including a database backbone, brain structure identification and localization, segmentation, registration, visual fea...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2005.03.012
更新日期：2005-09-01 00:00:00
abstract：:Control of blood glucose concentration for patients in intensive care units (ICUs) has been demonstrated to be beneficial in reducing mortality and the incidence of serious complications, for both diabetic and non-diabetic patients. However, the high degree of variability and uncertainty characterizing the physiologic...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2012.01.011
更新日期：2013-02-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Gallbladder polyp is a common disease with an overall population prevalence between 4 and 7%. It can be classified as neoplastic and non-neoplastic lesions. Surgical treatment is necessary for neoplastic polyps. Due to its easy accessibility and nonradioactive, ultrasonography is the mostly use...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105118
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVE AND BACKGROUND:This article featuring the peristaltic transport of viscous material with variable properties (i.e. temperature dependent viscosity and thermal conductivity) through curved configuration. Fluid saturating through porous channel walls of uniform space. Entropy generation consideration here is to...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105045
更新日期：2020-04-01 00:00:00
abstract：:Atrial fibrillation (AF) is the commonest arrhythmia, yet the mechanisms of its onset and persistence are incompletely known. Although techniques for quantitative assessment have been investigated, there have been few attempts to integrate this information to advance disease treatment protocols. In this review, key qu...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章,评审
doi：10.1016/j.cmpb.2019.06.017
更新日期：2019-09-01 00:00:00
abstract：:Analysis of longitudinal data is one of the most challenging tasks in statistical modeling. In the analysis, it is often necessary to take into account nonlinear response to a set of parameters of interest and correlation between measurements taken from the same individual. In addition, between- and within-subject var...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(97)00066-7
更新日期：1998-03-01 00:00:00
abstract：:This paper presents the control system design of a rehabilitation and training robot for the upper limbs. Based on a hierarchical structure, this control system allows the execution of sequence of switching control laws (position, force, impedance and force/impedance) corresponding to the required training configurati...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2007.07.006
更新日期：2008-02-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:In this note we propose a nonlinear programming approach for simultaneous fitting of quantile regression models for two or more quantiles. The approach is straightforward, flexible and practical. We apply this approach to a dataset of lactic acid values from a screening dataset in childhood mal...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.10.019
更新日期：2018-01-01 00:00:00
abstract：:The need for flexible and well understood knowledge representations which are capable of capturing clinical guidelines and protocols for decision support systems is widely recognised. The PROforma method for specifying clinical guidelines and protocols comprises a graphical notation for their design, and a formal know...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(97)00034-5
更新日期：1997-09-01 00:00:00
abstract：:The classical approach for extracting event-related potentials (ERPs) from the brain is ensemble averaging. For long latency ERPs this is not optimal, partly due to the time-delay in obtaining a response and partly because the latency and amplitude for the ERP components, like the P300, are variable and depend on cogn...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2009.12.006
更新日期：2010-09-01 00:00:00
abstract：:Hip fracture is more and more frequent in elderly population. For this reason, an increasing attention has been focused on the development of a non-invasive method to predict femoral neck fracture. A conventional approach to fracture diagnosis is the measurement of bone mass by dual-energy X-ray absorptiometry in some...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(99)00007-3
更新日期：1999-07-01 00:00:00
abstract：:Enhanced modified moving average method (EMMAM) and correlation method (CM) for microvolt TWA identification are compared by aid of simulated ECG tracings (cases of absence of TWA and presence of stationary or time-varying TWA) and ECG recordings from healthy subjects (H-group) and patients who survived an acute myoca...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2010.01.008
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:The large intra-patient variability in type 1 diabetic patients dramatically reduces the ability to achieve adequate blood glucose control. A novel methodology to identify different blood glucose dynamics profiles will allow therapies to be more accurate and tailored according to patient's conditions and to ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2016.08.022
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The traditional biomedical image retrieval methods as well as content-based image retrieval (CBIR) methods originally designed for non-biomedical images either only consider using pixel and low-level features to describe an image or use deep features to describe images but still leave a lot of...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2018.02.003
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Type 2 diabetes mellitus (T2DM) complications seriously affect the quality of life and could not be cured completely. Actions should be taken for prevention and self-management. Analysis of warning factors is beneficial for patients, on which some previous studies focused. They generally used t...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105302
更新日期：2020-05-01 00:00:00
abstract：:The computer program MISCAN is developed for use in evaluation of mass screening for disease. The program uses Monte Carlo simulation. It produces output on the results of screening projects and on the effects of screening on morbidity and mortality on the individual and population level. The calculations are based on...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(85)90048-3
更新日期：1985-05-01 00:00:00
abstract：:Analysis of multichannel ECG recordings (body surface maps (BSMs) and intracardial maps) requires special software. We created a software package and a user interface on top of a commercial data analysis package (MATLAB) by a combination of high-level and low-level programming. Our software was created to satisfy the ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(02)00014-7
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:For cancer detection from microscopic biopsy images, image segmentation step used for segmentation of cells and nuclei play an important role. Accuracy of segmentation approach dominate the final results. Also the microscopic biopsy images have intrinsic Poisson noise and if it is present in th...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.05.003
更新日期：2017-07-01 00:00:00
abstract：:The Intensive Care Unit (ICU) is an extremely data-intensive environment where each patient needs to be monitored 24/7. Bedside monitors continuously register vital patient values (such as serum creatinine, systolic blood pressure) which are recorded frequently in the hospital database (e.g. every 2 min in the ICU of ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2010.03.019
更新日期：2010-12-01 00:00:00
