Abstract:
BACKGROUND AND OBJECTIVE:In this note we propose a nonlinear programming approach for simultaneous fitting of quantile regression models for two or more quantiles. The approach is straightforward, flexible and practical. We apply this approach to a dataset of lactic acid values from a screening dataset in childhood malaria. METHODS:We carry out the fitting of simultaneous quantile regression models using a specific definition of a quantile as an expectation via nonlinear programming methods given certain monotonicity constraints. RESULTS:We illustrate through simulations and examples that are new approach to simultaneous quantile regression is practical and feasible. The approach is supplemented by providing a bootstrap framework for confidence interval estimation. CONCLUSIONS:Our nonlinear programming approach towards solving the simultaneous quantile regression fitting is shown to be a practical approach that should appeal to statistical practitioners.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Hutson ADdoi
10.1016/j.cmpb.2017.10.019subject
Has Abstractpub_date
2018-01-01 00:00:00pages
185-190eissn
0169-2607issn
1872-7565pii
S0169-2607(17)30355-3journal_volume
153pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVE:For more than 20 years, Higuchi's fractal dimension (HFD), as a nonlinear method, has occupied an important place in the analysis of biological signals. The use of HFD has evolved from EEG and single neuron activity analysis to the most recent application in automated assessments of different c...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章,评审
doi:10.1016/j.cmpb.2016.05.014
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Over the years, medical image registration has been widely used in various fields. However, different application characteristics, such as scale, computational complexity, and optimization goals, can cause problems. Therefore, developing an optimization algorithm based on clustering calculation is crucial. ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105432
更新日期:2020-08-01 00:00:00
abstract::This paper compares bibliographic retrieval using current MeSH (Medical Subject Headings) to bibliographic retrieval using explicitly coded semantic relationships between index terms. In a previous study, ten lists of abstracts, each list containing 20-40 papers discussing a specific pair of terms, were analyzed to id...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(88)90084-3
更新日期:1988-11-01 00:00:00
abstract:BACKGROUND AND AIMS:Coronary heart disease (CHD) is an important public health problem globally. Algorithms incorporating the assessment of clinical biomarkers together with several established traditional risk factors can help clinicians to predict CHD and support clinical decision making with respect to interventions...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2017.02.001
更新日期:2017-04-01 00:00:00
abstract::This paper presents a dialogue computer program, DIABLOG, for the education of diabetic patients with insulin therapy. Through mathematical modelling of glucose-insulin dynamics this program is able to simulate glucose and insulin profiles of a 24 h period and display them graphically as curves. The subjects could var...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(90)90114-o
更新日期:1990-07-01 00:00:00
abstract::The cumulative incidence function is commonly reported in studies with competing risks. The aim of this paper is to compute the treatment-specific cumulative incidence functions, adjusting for potentially imbalanced prognostic factors among treatment groups. The underlying regression model considered in this study is ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2010.07.005
更新日期:2011-01-01 00:00:00
abstract::Interventricular septum thickness in end-diastole (IVSd) is one of the key parameters in cardiology. This paper presents a fast algorithm, suitable for pocket-sized ultrasound devices, for measurement of IVSd using 2D B-mode parasternal long axis images. The algorithm is based on a deformable model of the septum and t...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2011.02.011
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In Duchenne Muscular Dystrophy (DMD) treatment, muscle fiber size can be considered as an indicator of muscle health and function. In particular, the statistical distribution of fibers cross-sectional areas (CSAs) has been used as quantitative efficacy endpoint. For each patient, assessment of ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.06.002
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The use of objective detection techniques applied to the auditory steady-state responses (ASSRs) for the assessment of auditory thresholds has been investigated over the years. The idea consists in setting up the audiometric profile without subjective inference from patients and evaluators. The...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2018.01.031
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Although the overall effect of particulate matter (PM) on cardiovascular disease (CVD) has been previously documented, the effect of different PM sizes (PM10, PM2.5-10 and PM2.5) has not been well studied. This study estimates the effect of different PM sizes on the incidence of CVD in Taipei, Taiwan. METHO...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2016.08.014
更新日期:2016-12-01 00:00:00
abstract::A parametric model for the ultrasound signals from blood and tissue is developed and a new imaging method, knowledge-based imaging, is defined. This method utilizes the likelihood ratio function to classify blood and tissue signals. The method separates blood and tissue signals by the difference in movement patterns i...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2009.03.012
更新日期:2009-10-01 00:00:00
abstract::In this study, the virtual reality (VR) proprioception rehabilitation system was developed for stroke patients to use proprioception feedback in upper limb rehabilitation by blocking visual feedback. To evaluate its therapeutic effect, 10 stroke patients (onset>3 month) trained proprioception feedback rehabilitation f...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2013.09.006
更新日期:2014-01-01 00:00:00
abstract::Mathematical modelling of infectious diseases has gained growing attention in epidemiology during the last decades. The major benefits of simulating compartmental models are the prediction of the consequences of potential interventions, a deeper understanding of epidemic dynamics and clinical decision support. The mai...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2010.05.007
更新日期:2011-11-01 00:00:00
abstract::This paper describes a distributed collaborative effort between industry and academia to systematize data management in an academic biomedical laboratory. Heterogeneous and voluminous nature of research data created in biomedical laboratories make information management difficult and research unproductive. One such co...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2015.11.001
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Several studies have evaluated the reproducibility of the Cobb angle for measuring the degree of scoliotic deformities from X-ray spine images, and proposed different geometric models for describing the spinal curvature. The ellipse was shown to be an adequate geometric form, but was not yet ap...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2018.04.015
更新日期:2018-07-01 00:00:00
abstract:INTRODUCTION:Being able to predict functional outcomes after a stroke is highly desirable for clinicians. This allows clinicians to set reasonable goals with patients and relatives, and to reach shared after-care decisions for recovery or rehabilitation. The aim of this study was to apply various machine learning (ML) ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105381
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Complementary and alternative medicine techniques have shown their potential for the treatment and diagnosis of chronical diseases like diabetes, arthritis etc. On the same time digital image processing techniques for disease diagnosis is reliable and fastest growing field in biomedical. Propos...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2018.01.004
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:This paper presents a Radial Basis Functions Neural Network (RBFNN) based detection system, for automatic identification of Cerebral Vascular Accidents (CVA) through analysis of Computed Tomographic (CT) images. METHODS:For the design of a neural network classifier, a Multi Objective Genetic Algorithm (MOGA)...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2017.05.005
更新日期:2017-07-01 00:00:00
abstract:PURPOSE:This study was performed to evaluate the usefulness of virtual magnetic resonance microscopy (VMRM) for the diagnosis of cerebral aneurysms. MATERIALS AND METHODS:We reviewed 11 patients with unruptured aneurysms confirmed by angiography or surgical therapy. We evaluated the ability of VMRM to represent aneury...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(01)00142-0
更新日期:2001-07-01 00:00:00
abstract::Ultrasound (US) imaging is one of the most popular techniques used in clinical diagnosis, mainly due to lack of adverse effects on patients and the simplicity of US equipment. However, the characteristics of the medium cause US imaging to imprecisely reconstruct examined tissues. The artifacts are the results of wave ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2016.07.034
更新日期:2016-10-01 00:00:00
abstract::Workplace description is an operation indispensable for the identification of professional risks and, in fulfillment of that objective, can best be accomplished by listing the constituent tasks associated with each job. This article presents a software in Visual-Basic to be run on a portable micro-computer, which faci...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(97)01777-x
更新日期:1997-01-01 00:00:00
abstract::This paper describes the open source framework MARVIN for rapid application development in the field of biomedical and clinical research. MARVIN applications consist of modules that can be plugged together in order to provide the functionality required for a specific experimental scenario. Application modules work on ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2008.04.007
更新日期:2008-08-01 00:00:00
abstract::Research in muscle physiology has progressed in both the volume and complexity of data examined. Dependence on manual methods to analyze and condense this amount of information can present a narrow bottleneck to the efficient completion of a study, and can compromise the reliability of the results. We designed a gener...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(89)90161-2
更新日期:1989-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Hand gesture recognition systems in operating rooms (ORs) are crucial for browsing and controlling computer-aided devices, which have been developed to decrease the risk of contamination during surgical procedures. METHODS:We proposed the use of hand gesture recognition to enhance accuracies a...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105385
更新日期:2020-07-01 00:00:00
abstract::Many clinical useful drugs have a narrow range of blood concentrations which are both safe and efficacious. Inter-individual and intra-individual variations in drug disposition are important factors causing blood concentrations of drug to fall outside of the therapeutic range. Modeling of the pharmacokinetics of the i...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(89)90069-2
更新日期:1989-10-01 00:00:00
abstract:OBJECTIVE:In cardiac medical imaging, the extraction and segmentation of the part of interest is the key to the diagnosis of heart disease. Due to irregular diastole and contraction, magnetic resonance imaging (MRI) images have poorly defined boundaries, and traditional segmentation algorithms have poor performance. In...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105755
更新日期:2020-12-01 00:00:00
abstract::We have developed a reference management system, MacRefer, using HyperTalk on Macintosh personal computers. Using this program, one can automatically acquire data from databases created by EndNote Plus and from OVID- or Medlar-formatted records downloaded via an online use of Medline. The MacRefer's capability of form...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(96)01731-2
更新日期:1996-06-01 00:00:00
abstract::Patient-specific geometric models are needed in many engineering problems. This work reports a novel software tool developed to construct individualized triangulated surface models from MR images. The program consists of three main parts: segmentation, triangulation and registration. The software tool was developed un...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(02)00125-6
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The technique of tri-cortical pedicle screw (TCPS) has been used to improve the anchoring strength in the sacral vertebrae. However, no studies have reported their application in the thoracic vertebrae. Our research is aimed to assess the stability and strength of the TCPS in thoracic vertebrae...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.105035
更新日期:2020-04-01 00:00:00
abstract::Non-carious cervical lesions are characterized by the loss of dental hard tissue at the cement-enamel junction (CEJ). Exceeding stresses are therefore generated in the cervical region of the tooth that cause disruption of the bonds between the hydroxyapatite crystals, leading to crack formation and eventual loss of en...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2010.06.009
更新日期:2011-08-01 00:00:00