Abstract：
:Research in muscle physiology has progressed in both the volume and complexity of data examined. Dependence on manual methods to analyze and condense this amount of information can present a narrow bottleneck to the efficient completion of a study, and can compromise the reliability of the results. We designed a general purpose computerized system for data acquisition in experiments in our cardiovascular physiology laboratory. In addition, we developed a software program specifically for the analysis of data from studies of isolated, isometrically contracting myocardium. This system has reduced the time for analysis of such data by approximately 50-fold over that of manual techniques, and has contributed significantly to our confidence in the measured results.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Stanley TE 3rd,Held JP,Estrin JAdoi
10.1016/0169-2607(89)90161-2subject
Has Abstractpub_date
1989-04-01 00:00:00pages
273-9issue
4eissn
0169-2607issn
1872-7565pii
0169-2607(89)90161-2journal_volume
28pub_type
杂志文章abstract：CONTEXT:People who have recently recovered from the threat of deteriorating coronavirus disease-2019 (COVID-19) have antibodies to the coronavirus circulating in their blood. Thus, the transfusion of these antibodies to deteriorating patients could theoretically help boost their immune system. Biologically, two challen...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105617
更新日期：2020-11-01 00:00:00
abstract：:Role of hepatic insulin degradation in modulating insulin delivery to peripheral circulation, in insulin-resistant hypertensive patients, is not yet fully understood. This issue was investigated here by a novel application to hypertension of a previously proposed minimal modelling of insulin and C-peptide data, using ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2009.08.007
更新日期：2010-02-01 00:00:00
abstract：:Glucose-insulin system models are commonly used for identifying insulin sensitivity. With physiological, 2-compartment insulin kinetics models, accurate kinetic parameter values are required for reliable estimates of insulin sensitivity. This study uses data from 6 published microdialysis studies to determine the most...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2014.01.011
更新日期：2014-05-01 00:00:00
abstract：:A physician's problem-solving performance improves with experience. The performance of most medical expert systems does not. The author has developed a diagnosis program for coronary disease that improves its performance by remembering and learning from cases that it has already solved. The program diagnoses commonly-...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(89)90070-9
更新日期：1989-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Type 2 diabetes mellitus (T2DM) complications seriously affect the quality of life and could not be cured completely. Actions should be taken for prevention and self-management. Analysis of warning factors is beneficial for patients, on which some previous studies focused. They generally used t...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105302
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Hedyotis diffusa is an herb used for anti-cancer, anti-oxidant, anti-inflammatory, and anti-fibroblast treatment in the clinical practice of Traditional Chinese Medicine. However, its pharmacological mechanisms have not been fully established and there is a lack of modern scientific verificatio...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2018.10.019
更新日期：2019-06-01 00:00:00
abstract：INTRODUCTION:Being able to predict functional outcomes after a stroke is highly desirable for clinicians. This allows clinicians to set reasonable goals with patients and relatives, and to reach shared after-care decisions for recovery or rehabilitation. The aim of this study was to apply various machine learning (ML) ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105381
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:The purpose of the study was to probe into the changes in life expectancy associated with schooling years found by the Organization for Economic Co-operation and Development (OECD). METHODS:The study was based on the OECD database from the period 2000 to 2006. The data of thirty countries were constructed t...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2013.11.016
更新日期：2014-03-01 00:00:00
abstract：:This paper presents the control system design of a rehabilitation and training robot for the upper limbs. Based on a hierarchical structure, this control system allows the execution of sequence of switching control laws (position, force, impedance and force/impedance) corresponding to the required training configurati...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2007.07.006
更新日期：2008-02-01 00:00:00
abstract：:The computer program MISCAN is developed for use in evaluation of mass screening for disease. The program uses Monte Carlo simulation. It produces output on the results of screening projects and on the effects of screening on morbidity and mortality on the individual and population level. The calculations are based on...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(85)90048-3
更新日期：1985-05-01 00:00:00
abstract：:The long-term variability of the fetal heart rate (FHR) provides valuable information on the fetal health status. The routine clinical FHR measurements are usually carried out by the means of ultrasound cardiography. Although the frequent FHR monitoring is recommendable, the high quality ultrasound devices are so expe...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(02)00111-6
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:In this study, a wireless blood pressure holter that can be used with smart mobile devices was developed. The developed blood pressure holter consists of two parts, which are a smart mobile device and a cuff. The smart mobile device is used as a recording, control and display device through a d...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.12.025
更新日期：2018-03-01 00:00:00
abstract：:Radiologic and clinical practice can be enhanced by improved access to multimodal image information. Analysis, visualization, method characteristic image processing and image synthesis is needed not only for the interpretation of the images but also for performing effective consultations with clinical colleagues and c...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(94)90070-1
更新日期：1994-06-01 00:00:00
abstract：:Model reduction techniques have shown to constitute a valuable tool for real-time simulation in surgical environments and other fields. However, some limitations, imposed by real-time constraints, have not yet been overcome. One of such limitations is the severe limitation in time (established in 500Hz of frequency fo...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2010.06.012
更新日期：2012-01-01 00:00:00
abstract：:The popularity of the use of Apple II/IIe hardware in medical applications is evidenced by the variety of articles devoted to the use of this hardware in biomedical research and medical practice. Many of these applications are of a stochastic nature, including simulations, and depend on the Applesoft random number gen...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(88)90002-8
更新日期：1988-05-01 00:00:00
abstract：PURPOSE:Computed tomography (CT) volume sets reconstructed with different kernels are helping to increase diagnostic accuracy. However, several CT volumes reconstructed with different kernels are difficult to sustain, due to limited storage and maintenance issues. A CT kernel conversion method is proposed using convolu...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105615
更新日期：2020-11-01 00:00:00
abstract：:We propose a specially optimized computer program for the user-independent calculation of the correlation dimension D and the largest Lyapunov exponent L of heart rate dynamics on the basis of only 1024 electrocardiographically recorded RR intervals (heartbeat intervals). The validity of our program was established by...
journal_title：Computer methods and programs in biomedicine
pub_type： 临床试验,杂志文章
doi：10.1016/0169-2607(95)01707-0
更新日期：1996-01-01 00:00:00
abstract：:A simple microcomputer crossover program in BASIC is designed for the purpose of drug bioequivalence studies and other related fields of statistical investigation. An illustration of the application of the program is presented to compare the bioavailability of ibuprofen when administered alone or followed by colestipo...
journal_title：Computer methods and programs in biomedicine
pub_type： 临床试验,杂志文章
doi：10.1016/0169-2607(95)01695-3
更新日期：1995-12-01 00:00:00
abstract：:This article was motivated by the doctors' demand to make a technical support in pathologies of gastrointestinal tract research [10], which would be based on machine vision tools. Proposed solution should be less expensive alternative to already existing RF (radio frequency) methods. The objective of whole experiment ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2015.12.009
更新日期：2016-04-01 00:00:00
abstract：:Mathematical modelling of infectious diseases has gained growing attention in epidemiology during the last decades. The major benefits of simulating compartmental models are the prediction of the consequences of potential interventions, a deeper understanding of epidemic dynamics and clinical decision support. The mai...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2010.05.007
更新日期：2011-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:This contribution presents a rapid computational framework to mechanically simulate the insertion of a slender medical instrument in a tubular structure such as an artery, the cochlea or another slender instrument. METHODS:Beams are employed to rapidly simulate the mechanical behaviour of the ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105527
更新日期：2020-11-01 00:00:00
abstract：:The purpose of this study was to evaluate the clinical efficacy of 3D reconstruction of the tracheobronchial system using spiral CT. A total of 25 patients with tracheobronchial abnormalities, stenosis (n = 21) and fistula with esophagus (n = 4), underwent a single breathhold spiral CT (5 mm collision, 5 mm)/s increme...
journal_title：Computer methods and programs in biomedicine
pub_type： 临床试验,杂志文章
doi：10.1016/s0169-2607(98)00053-4
更新日期：1998-08-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Drug-target interaction prediction plays an intrinsic role in the drug discovery process. Prediction of novel drugs and targets helps in identifying optimal drug therapies for various stringent diseases. Computational prediction of drug-target interactions can help to identify potential drug-ta...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2018.08.011
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The anatomical structure detection in retinal images is an open problem. However, most of the works in the related literature are oriented to the detection of each structure individually or assume the previous detection of a structure which is used as a reference. The objective of this paper is...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.06.022
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Capturing the context of text is a challenging task in biomedical text summarization. The objective of this research is to show how contextualized embeddings produced by a deep bidirectional language model can be utilized to quantify the informative content of sentences in biomedical text summa...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105117
更新日期：2020-02-01 00:00:00
abstract：:The lower urinary tract is one of the most complex biological systems of the human body as it involved hydrodynamic properties of urine and muscle. Moreover, its complexity is increased to be managed by voluntary and involuntary neural systems. In this paper, a mathematical model of the lower urinary tract it is propo...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2012.09.005
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Univariate feature selection is one of the simplest and most commonly used techniques to develop a multigene predictor for survival. Presently, there is no software tailored to perform univariate feature selection and predictor construction. METHODS:We develop the compound.Cox R package that i...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2018.10.020
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Automated segmentation with high accuracy and speed is a prerequisite for FEA-based quantitative assessment with a large population. However, hip joint segmentation has remained challenging due to a narrow articular cartilage and thin cortical bone with a marked interindividual variance. To ove...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.11.007
更新日期：2018-02-01 00:00:00
abstract：:An outline of the Hokkaido University PACS (HU-PACS) and 10 months experience of its clinical use are reported. It is concluded that HU-PACS is a useful clinical tool, even though some points still remain to be improved. ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(91)90049-y
更新日期：1991-10-01 00:00:00
abstract：:In muscle cells, force development is controlled by Ca2+ ions, which are rapidly released from the sarcoplasmic reticulum (SR) during sarcolemmal depolarization. In addition to this synchronized spatially homogeneous calcium signal, localized quantal Ca2+ release events (sparks) have been recorded using laser scanning...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2004.06.004
更新日期：2005-01-01 00:00:00
