A program for the user-independent computation of the correlation dimension and the largest Lyapunov exponent of heart rate dynamics from small data sets.

Abstract:

:We propose a specially optimized computer program for the user-independent calculation of the correlation dimension D and the largest Lyapunov exponent L of heart rate dynamics on the basis of only 1024 electrocardiographically recorded RR intervals (heartbeat intervals). The validity of our program was established by analyzing a set of artificial standard signals. Our norm values of the correlation dimension (D = 5.37 +/- 0.62) and the largest Lyapunov exponent (L = 0.561 +/- 0.037 bits/beat) of RR dynamics, obtained from 79 healthy adults aged 26.3 +/- 4.8 years, were independent of gender and age; D and L correlated slightly with each other (Pearson correlation coefficient r = 0.26). Short-term reliability, tested for 25 of our subjects by two successive recordings, was fair: the intraclass correlation coefficients (ICCs) were 0.45 and 0.41 for D and L of RR dynamics, respectively. However, long-term reliability, tested for eight of our subjects by ten weekly recordings, was acceptable for L (ICC = 0.40) but not for D (ICC = 0.01). These results permit group comparisons on the basis of single measurements of L of RR dynamics. A reliable differentiation between young healthy individuals requires four measurements of L.

authors

Ganz RE,Lenz C

doi

10.1016/0169-2607(95)01707-0

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

61-8

issue

1

eissn

0169-2607

issn

1872-7565

pii

0169260795017070

journal_volume

49

pub_type

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