Abstract：
:Statistical tests are often performed to discover which experimental variables are reacting to specific treatments. Time-series statistical models usually require the researcher to make assumptions with respect to the distribution of measured responses which may not hold. Randomization tests can be applied to data in order to generate null distributions non-parametrically. However, large numbers of randomizations are required for the precise p-values needed to control false discovery rates. When testing tens of thousands of variables (genes, chemical compounds, or otherwise), significant q-value cutoffs can be extremely small (on the order of 10(-5) to 10(-8)). This requires high-precision p-values, which in turn require large numbers of randomizations. The NVIDIA(®) Compute Unified Device Architecture(®) (CUDA(®)) platform for General Programming on the Graphics Processing Unit (GPGPU) was used to implement an application which performs high-precision randomization tests via Monte Carlo sampling for quickly screening custom test statistics for experiments with large numbers of variables, such as microarrays, Next-Generation sequencing read counts, chromatographical signals, or other abundance measurements. The software has been shown to achieve up to more than 12 fold speedup on a Graphics Processing Unit (GPU) when compared to a powerful Central Processing Unit (CPU). The main limitation is concurrent random access of shared memory on the GPU. The software is available from the authors.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Van Hemert JL,Dickerson JAdoi
10.1016/j.cmpb.2010.04.010subject
Has Abstractpub_date
2011-01-01 00:00:00pages
80-6issue
1eissn
0169-2607issn
1872-7565pii
S0169-2607(10)00095-7journal_volume
101pub_type
杂志文章abstract：:The noninvasive fetal electrocardiography is a source of more precise information on the fetal heart activity than the measurements based on Doppler ultrasound signals. However, the clinical diagnostic applications of this technique are limited by difficulty with successful detection of small amplitude fetal QRS compl...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2009.09.005
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Accurate, reliable, efficient, and precise measurements of the lumen geometry of the common carotid artery (CCA) are important for (a) managing the progression/regression of atherosclerotic build-up and (b) the risk of stroke. The image-based degree of stenosis in the carotid artery and the pla...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章,评审
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2018.04.015
更新日期：2018-07-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
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journal_title：Computer methods and programs in biomedicine
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doi：10.1016/s0169-2607(01)00132-8
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2014.06.004
更新日期：2014-10-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2013.05.002
更新日期：2013-08-01 00:00:00
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doi：10.1016/j.cmpb.2019.105200
更新日期：2020-04-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2004.12.007
更新日期：2005-05-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(94)90080-9
更新日期：1994-06-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(94)90139-2
更新日期：1994-02-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.05.003
更新日期：2017-07-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2010.01.002
更新日期：2010-07-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2009.11.001
更新日期：2010-07-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(87)90066-6
更新日期：1987-02-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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doi：10.1016/j.cmpb.2016.10.011
更新日期：2017-01-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.06.002
更新日期：2019-09-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2005.06.010
更新日期：2005-11-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
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journal_title：Computer methods and programs in biomedicine
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doi：10.1016/j.cmpb.2009.04.006
更新日期：2009-11-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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更新日期：2021-01-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2013.06.009
更新日期：2013-10-01 00:00:00
abstract：:Electroencephalogram (EEG) has established itself as an important means of identifying and analyzing epileptic seizure activity in humans. In most cases, identification of the epileptic EEG signal is done manually by skilled professionals, who are small in number. In this paper, we try to automate the detection proces...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2008.02.005
更新日期：2008-08-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2015.09.008
更新日期：2015-12-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(96)01794-4
更新日期：1997-03-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2016.02.014
更新日期：2016-06-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2012.08.013
更新日期：2012-12-01 00:00:00
abstract：:Due to organizational and technological changes the need for integrating information systems within healthcare institutions, has increased enormously. Although the technical means for systems integration have definitely matured, integration methodologies are still in their infancy. Two important questions regarding sy...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(00)00086-9
更新日期：2001-01-01 00:00:00
