Abstract：
:The impact of a problem based curriculum has been the subject of increasing interest, as evidenced by several recent articles on the subject [1-4]. McMaster was able to design its library to serve a problem-based curriculum, but since there had been no prior experience with such a curriculum, the library was designed to meet needs that could only be guessed at [5]. In addition, the library serves the needs of a research intensive faculty. How the curriculum and the library have interacted over the past 25 years may be helpful to other schools considering problem-based learning.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Blake Jdoi
10.1016/0169-2607(94)90110-4subject
Has Abstractpub_date
1994-09-01 00:00:00pages
167-73issue
3-4eissn
0169-2607issn
1872-7565pii
0169-2607(94)90110-4journal_volume
44pub_type
杂志文章abstract：BACKGROUND AND OBJECTIVE:Hypokinetic dysarthria (HD) is a frequent speech disorder associated with idiopathic Parkinson's disease (PD). It affects all dimensions of speech production. One of the most common features of HD is dysprosody that is characterized by alterations of rhythm and speech rate, flat speech melody, ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2015.12.011
更新日期：2016-04-01 00:00:00
abstract：:Methods for evaluating a single diagnostic test with reference to the disease prevalence in a given population include sensitivity, specificity, positive predictive value, negative predictive value, and accuracy. Patient disease status and, ultimately, the treatment course is determined by the outcome of these diagnos...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(91)90119-e
更新日期：1991-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:In recent years, many attempts have been made to design reliable systems for identifying individuals using biometrics. Electrocardiogram (ECG) biometric is one of the newest methods that not only offers unique characteristics of individuals for human identification, but also the possibility of ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.02.009
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Tomographic sequences of biomedical images are commonly used to achieve a three-dimensional visualization of the human anatomy. In some cases, the number of images contained in the sequence is limited, e.g., in low-dose computed tomography acquired on neonatal patients, resulting in a coarse an...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105525
更新日期：2020-10-01 00:00:00
abstract：:There are currently 501 hospitals and about 20,000 clinics in Taiwan. The National Health Insurance (NHI) system, which is operated by the NHI Administration, uses a single-payer system and covers 99.9% of the nation's total population of 23,000,000. Taiwan's NHI provides people with a high degree of freedom in choosi...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2015.04.013
更新日期：2015-08-01 00:00:00
abstract：:This paper is concerned with the investigation on the fatigue failure of implant fixation by numerical approaches. A computer algorithm based on finite element analysis and continuum damage mechanics was proposed to quantify the fatigue damage rate of cement mantle under physiological conditions. In examining the inte...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2004.05.004
更新日期：2004-11-01 00:00:00
abstract：:The paper presents a computer-based assessment for facioscapulohumeral dystrophy (FSHD) diagnosis through characterisation of the fat and oedema percentages in the muscle region. A novel multi-slice method for the muscle-region segmentation in the T1-weighted magnetic resonance images is proposed using principles of t...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2015.03.006
更新日期：2015-06-01 00:00:00
abstract：:In this article the development of a computer system for General Practice, ELIAS, is described. The use of the 4th-generation software toolkit AIDA proved to be very helpful in increasing the speed of development as well as the quality of the ELIAS software. The programming support that AIDA offered, not only in incre...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(87)90086-1
更新日期：1987-11-01 00:00:00
abstract：:Fall detection, gait analysis and context recognition are examples of applications where capacitive accelerometers are widely used in health care. In most of the existing work, algorithms were developed for a specific platform and accelerometers were used without explicitly choosing a specific type. With this work we ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2011.10.009
更新日期：2012-05-01 00:00:00
abstract：:This work provides a performance comparison of four different machine learning classifiers: multinomial logistic regression with ridge estimators (MLR) classifier, k-nearest neighbours (KNN), support vector machine (SVM) and naïve Bayes (NB) as applied to terahertz (THz) transient time domain sequences associated with...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2016.01.017
更新日期：2016-04-01 00:00:00
abstract：:A new iterative polyexponential curve stripping technique for the provision of initial pharmacokinetic parameter estimates has been developed. Such estimates are required for nonlinear least-squares curve fitting. In contrast to conventional curve stripping, this new technique does not make any assumption about the re...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(85)90085-9
更新日期：1985-08-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:For diagnosis of arrhythmic heart problems, electrocardiogram (ECG) signals should be recorded and monitored. The long-term signal records obtained are analyzed by expert cardiologists. Devices such as the Holter monitor have limited hardware capabilities. For improved diagnostic capacity, it w...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.05.004
更新日期：2019-07-01 00:00:00
abstract：:Many clinical useful drugs have a narrow range of blood concentrations which are both safe and efficacious. Inter-individual and intra-individual variations in drug disposition are important factors causing blood concentrations of drug to fall outside of the therapeutic range. Modeling of the pharmacokinetics of the i...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(89)90069-2
更新日期：1989-10-01 00:00:00
abstract：PURPOSE:This study was performed to evaluate the usefulness of virtual magnetic resonance microscopy (VMRM) for the diagnosis of cerebral aneurysms. MATERIALS AND METHODS:We reviewed 11 patients with unruptured aneurysms confirmed by angiography or surgical therapy. We evaluated the ability of VMRM to represent aneury...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(01)00142-0
更新日期：2001-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Early diagnosis of cardiac autonomic neuropathy (CAN) is critical for reversing or decreasing its progression and prevent complications. Diagnostic accuracy or precision is one of the core requirements of CAN detection. As the standard Ewing battery tests suffer from a number of shortcomings, r...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2018.01.019
更新日期：2018-07-01 00:00:00
abstract：:NONMEM is an extremely powerful tool for nonlinear mixed-effect modelling and simulation of pharmacokinetic and pharmacodynamic data. However, it is a console-based application whose output does not lend itself to rapid interpretation or efficient management. NONMEMory has been created to be a comprehensive project ma...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2005.02.003
更新日期：2005-06-01 00:00:00
abstract：:A convolution program (CONV) solving responses to a collimated finite diameter photon beam perpendicularly incident on a multi-layered tissue has been coded in ANSI Standard C, hence, the program can be executed on various computers. The program, employing an extended trapezoidal rule for integration, convolves the re...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(97)00021-7
更新日期：1997-11-01 00:00:00
abstract：UNLABELLED:This paper presents two new ideas. The first one is to apply the Viola integral waveform method to analyze the heart sounds recorded by an electric stethoscope, and the multi-scale moment analysis is proposed to locate each cycle of heart sounds. A fast algorithm for calculating characteristic waveform (CW) ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2009.09.008
更新日期：2010-05-01 00:00:00
abstract：:In this study, the virtual reality (VR) proprioception rehabilitation system was developed for stroke patients to use proprioception feedback in upper limb rehabilitation by blocking visual feedback. To evaluate its therapeutic effect, 10 stroke patients (onset>3 month) trained proprioception feedback rehabilitation f...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2013.09.006
更新日期：2014-01-01 00:00:00
abstract：:Karyotype analysis is a widespread procedure in cytogenetics to assess the presence of genetic defects by the visualization of the structure of chromosomes. The procedure is lengthy and repetitive and an effective automatic analysis would greatly help the cytogeneticist routine work. Still, automatic segmentation and ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章,评审
doi：10.1016/j.cmpb.2011.12.003
更新日期：2012-11-01 00:00:00
abstract：:The aim of segmentation of tumor regions in positron emission tomography (PET) is to provide more accurate measurements of tumor size and extension into adjacent structures, than is possible with visual assessment alone and hence improve patient management decisions. We propose a segmentation energy function for the g...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2012.10.009
更新日期：2013-03-01 00:00:00
abstract：:This paper presents a new method for the construction of three-dimensional (3D) probabilistic facial averages and demonstrates the potential for applications in clinical craniofacial research and patient assessment. Averages are constructed from a database of registered laser-range scans and photographic images using ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(00)00072-9
更新日期：2000-08-01 00:00:00
abstract：:Closed-loop insulin delivery systems often implement glucose measurement and insulin administration in the subcutis. However some existing models for glucose-insulin system ignored the dynamics of subcutaneous glucose and subcutaneously-injected insulin. This paper reports a two-compartment model that includes glucose...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2013.05.001
更新日期：2013-08-01 00:00:00
abstract：:The popularity of the use of Apple II/IIe hardware in medical applications is evidenced by the variety of articles devoted to the use of this hardware in biomedical research and medical practice. Many of these applications are of a stochastic nature, including simulations, and depend on the Applesoft random number gen...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(88)90002-8
更新日期：1988-05-01 00:00:00
abstract：BACKGROUND:The aim of this articles is to investigate the entropy optimization in Darcy-Forchheimer hybrid nanofluids flow towards a stretchable surface. The flow is caused due to stretching of surface. Energy equation is discussed through heat generation/absorption, viscous dissipation and heat flux. Here molybdenum d...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105152
更新日期：2020-03-01 00:00:00
abstract：:Elderly people are commonly affected by Parkinson's disease (PD) which is one of the most common neurodegenerative disorders due to the loss of dopamine-producing brain cells. People with PD's (PWP) may have difficulty in walking, talking or completing other simple tasks. Variety of medications is available to treat P...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2014.01.004
更新日期：2014-03-01 00:00:00
abstract：:The lower urinary tract is one of the most complex biological systems of the human body as it involved hydrodynamic properties of urine and muscle. Moreover, its complexity is increased to be managed by voluntary and involuntary neural systems. In this paper, a mathematical model of the lower urinary tract it is propo...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2012.09.005
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:There is a huge amount of rare diseases, many of which have associated important disabilities. It is paramount to know in advance the evolution of the disease in order to limit and prevent the appearance of disabilities and to prepare the patient to manage the future difficulties. Rare disease ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2018.07.007
更新日期：2018-10-01 00:00:00
abstract：:Cardiac MR image-based predictive models integrating statistical atlases of heart anatomy and fiber orientations can aid in better diagnosis of cardiovascular disease, a major cause of death worldwide. Such atlases have been built from diffusion tensor (DT) images and can be used in anisotropic models for personalized...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105200
更新日期：2020-04-01 00:00:00
abstract：:We present three mathematical models which simulate the wound healing time for 10% oil-resin (10% OR), 10% hydroalcoholic extract (10% EH) (Copaifera langsdorffii drugs), Lanette cream (LC) and Collagenase treatments. Wound healing is a complex process consisting of inflammatory, proliferative and remodelling phases. ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105915
更新日期：2020-12-26 00:00:00
