Abstract：
:The aim of the present study was to design, implement and evaluate a software system for discriminating between metastatic and primary brain tumors (gliomas and meningiomas) on MRI, employing textural features from routinely taken T1 post-contrast images. The proposed classifier is a modified probabilistic neural network (PNN), incorporating a non-linear least squares features transformation (LSFT) into the PNN classifier. Thirty-six textural features were extracted from each one of 67 T1-weighted post-contrast MR images (21 metastases, 19 meningiomas and 27 gliomas). LSFT enhanced the performance of the PNN, achieving classification accuracies of 95.24% for discriminating between metastatic and primary tumors and 93.48% for distinguishing gliomas from meningiomas. To improve the generalization of the proposed classification system, the external cross-validation method was also used, resulting in 71.43% and 81.25% accuracies in distinguishing metastatic from primary tumors and gliomas from meningiomas, respectively. LSFT improved PNN performance, increased class separability and resulted in dimensionality reduction.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Georgiadis P,Cavouras D,Kalatzis I,Daskalakis A,Kagadis GC,Sifaki K,Malamas M,Nikiforidis G,Solomou Edoi
10.1016/j.cmpb.2007.10.007subject
Has Abstractpub_date
2008-01-01 00:00:00pages
24-32issue
1eissn
0169-2607issn
1872-7565pii
S0169-2607(07)00240-4journal_volume
89pub_type
杂志文章abstract：BACKGROUND AND OBJECTIVE:The primary objective of present analysis is to model the peristalsis of copper-water based nanoliquid in the presence of first order velocity and thermal slip conditions in a curved channel. Mixed convection, viscous dissipation and heat generation/absorption are also accounted. METHOD:Mathem...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.02.006
更新日期：2017-04-01 00:00:00
abstract：:This paper describes the open source framework MARVIN for rapid application development in the field of biomedical and clinical research. MARVIN applications consist of modules that can be plugged together in order to provide the functionality required for a specific experimental scenario. Application modules work on ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2008.04.007
更新日期：2008-08-01 00:00:00
abstract：:The computer program MISCAN is developed for use in evaluation of mass screening for disease. The program uses Monte Carlo simulation. It produces output on the results of screening projects and on the effects of screening on morbidity and mortality on the individual and population level. The calculations are based on...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(85)90048-3
更新日期：1985-05-01 00:00:00
abstract：:The effects of slip condition and Joule heating on the peristaltic flow of Bingham nanofluid are investigated. The flow is taken in a porous channel with elastic walls. Mathematical formulation is presented under the assumption of long wavelength and small Reynolds number. The transformed equations for the flow are so...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105005
更新日期：2019-10-01 00:00:00
abstract：:The microcomputer program presented here allows the simulation of linear compartmental physiological models whose structure is known. The method used is the 4th order Runge-Kutta method. Implemented on the Apple IIe, this program is fully interactive and presents the possibility of changing model parameters or initial...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(87)90066-6
更新日期：1987-02-01 00:00:00
abstract：:A program, AQ, has been developed to perform analog-to-digital (A/D) conversions on IBM PC products using the Data Translation DT2801-A or DT2801 boards. This program provides support for all of the triggered and continuous A/D modes of these boards. Additional subroutines for management of data files and display of a...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(86)90067-2
更新日期：1986-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Stable isotope labeling by amino acids in cell culture (SILAC) is a practical and powerful approach for quantitative proteomic analysis. A key advantage of SILAC is the ability to simultaneously detect the isotopically labeled peptides in a single instrument run and so guarantee relative quanti...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2016.09.017
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Ankle sprain is the most common sports-related injury, and approximately 80% of patients studied suffered recurrent sprains. These repeated ankle injuries could cause chronic ankle instability, a decrease in sports performance, and a decrease in postural control ability. At the present time, smartphones have...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2016.11.005
更新日期：2017-02-01 00:00:00
abstract：:Contrast and brightness matching are often required in many medical imaging applications, especially when comparing medical data acquired over different time periods, due to dissimilarities in the acquisition process. Numerous methods have been proposed in this field, ranging from simple correction filters to more com...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2011.03.011
更新日期：2012-06-01 00:00:00
abstract：:The very first step for keeping good dental hygiene is to employ the correct toothbrushing style. Due to the possible occurrence of periodontal disease at an early age, it is critical to begin correct toothbrushing patterns as early as possible. With this aim, we proposed a novel toothbrush monitoring and training sys...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2009.04.006
更新日期：2009-11-01 00:00:00
abstract：:The standard software for non-linear mixed-effect analysis of pharmacokinetic/pharmacodynamic (PK/PD) data is NONMEM while the non-linear mixed-effects package NLME is an alternative as long as the models are fairly simple. We present the nlmeODE package which combines the ordinary differential equation (ODE) solver p...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2004.01.001
更新日期：2004-10-01 00:00:00
abstract：:The primary aim of the Improved Monitoring for Brain Dysfunction during Intensive Care and Surgery (IBIS) project was to create a unique and comprehensively annotated data library (DL) of multiple physiological, including neurophysiological, signals. Data collection was undertaken in Kuopio, Finland and London, UK, an...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(00)00107-3
更新日期：2000-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Automatic osteosarcoma tumor segmentation on computed tomography (CT) images is a challenging problem, as tumors have large spatial and structural variabilities. In this study, an automatic tumor segmentation method, which was based on a fully convolutional networks with multiple supervised sid...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2017.02.013
更新日期：2017-05-01 00:00:00
abstract：:This paper compares bibliographic retrieval using current MeSH (Medical Subject Headings) to bibliographic retrieval using explicitly coded semantic relationships between index terms. In a previous study, ten lists of abstracts, each list containing 20-40 papers discussing a specific pair of terms, were analyzed to id...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(88)90084-3
更新日期：1988-11-01 00:00:00
abstract：:Glaucoma is a destructive eye disease that causes blindness in individuals displaying little or no symptoms. There is no cure as yet though there are treatments that can arrest its effects or slow its development. The earlier the disease is detected, the more likely the treatment will be successful; however early dete...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2005.01.002
更新日期：2005-08-01 00:00:00
abstract：PURPOSE:develop and validate a PET sorting algorithm based on the respiratory amplitude to correct for abnormal respiratory cycles. METHOD AND MATERIALS:using the 4D NCAT phantom model, 3D PET images were simulated in lung and other structures at different times within a respiratory cycle and noise was added. To valid...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2007.05.004
更新日期：2007-08-01 00:00:00
abstract：:metrumrg is an R package that facilitates workflow for the discipline of pharmacometrics. Support is provided for data preparation, modeling, simulation, diagnostics, and reporting. Existing tools and techniques are emphasized where available; original solutions are provided for otherwise unmet needs. In particular, m...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2012.08.009
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Strabismus is an eye movement disorder in which shows the abnormal ocular deviation. Cover tests have mainly been used in the clinical diagnosis of strabismus for treatment. However, the whole process depends on the doctor's level of experience, which could be subjected to several factors. In t...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2019.105132
更新日期：2020-03-01 00:00:00
abstract：:A veterinary anatomy tutoring system was developed by using Knowledge Pro, an object-oriented software development tool with hypermedia capabilities, and MS Access, a relational database. Communication between them is facilitated by using the Structured Query Language (SQL). The architecture of the system is based on ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(94)90045-0
更新日期：1994-02-14 00:00:00
abstract：OBJECTIVE:In cardiac medical imaging, the extraction and segmentation of the part of interest is the key to the diagnosis of heart disease. Due to irregular diastole and contraction, magnetic resonance imaging (MRI) images have poorly defined boundaries, and traditional segmentation algorithms have poor performance. In...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105755
更新日期：2020-12-01 00:00:00
abstract：:We present three mathematical models which simulate the wound healing time for 10% oil-resin (10% OR), 10% hydroalcoholic extract (10% EH) (Copaifera langsdorffii drugs), Lanette cream (LC) and Collagenase treatments. Wound healing is a complex process consisting of inflammatory, proliferative and remodelling phases. ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105915
更新日期：2020-12-26 00:00:00
abstract：:This paper introduces temporal logics. Due to the eternal compromise between expressive adequacy and reasoning efficiency that must decided upon in any application, full (first order logic or modal logic based) temporal logics are frequently not suitable. This is especially true in real time expert systems, where a fi...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章,评审
doi：10.1016/0169-2607(96)01761-0
更新日期：1996-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Frozen-thawed embryo transfer (FET) is now widely used for the treatment of infertility. For many couples and clinicians, concerns over the probability and how to increase the chance of a successful birth are very common. Currently, there is not a single model to predict the live birth outcomes...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2020.105780
更新日期：2021-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Early detection of cardiovascular (CV) disease or associated risk factors during childhood is of paramount importance, allowing for early treatment or lifestyle modifications, respectively. The objective of this study was to describe the development of an electronic health record (EHR), with in...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2018.03.009
更新日期：2018-06-01 00:00:00
abstract：:Endoscopy is used for inspection of the inner surface of organs such as the colon. During endoscopic inspection of the colon or colonoscopy, a tiny video camera generates a video signal, which is displayed on a monitor for interpretation in real-time by physicians. In practice, these images are not typically captured,...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2011.04.003
更新日期：2012-11-01 00:00:00
abstract：:The urinary flow rates of normal individuals depend on the initial bladder volume in a non-linear fashion (J. Urol. 109 (1973) 874). A flow rate nomogram was developed by Siroky, Olsson and Krane, (J. Vol. 122 (1979) 665), taking the non-linear relationship into account, as an aid in the interpretation of urinary flow...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(93)90030-o
更新日期：1993-04-01 00:00:00
abstract：:Closed-loop insulin delivery systems often implement glucose measurement and insulin administration in the subcutis. However some existing models for glucose-insulin system ignored the dynamics of subcutaneous glucose and subcutaneously-injected insulin. This paper reports a two-compartment model that includes glucose...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2013.05.001
更新日期：2013-08-01 00:00:00
abstract：:There are numerous programs ongoing to analyze environmental exposure of humans to xenobiotic chemicals via biomonitoring measurements (e.g.: EU ESBIO, COPHES; US CDC NHANES; Canadian Health Measures Survey). The goal of these projects is to determine relative trends in exposure to chemicals, across time and subpopula...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2012.04.014
更新日期：2012-11-01 00:00:00
abstract：:A minimal model of the cardio-vascular system (CVS) with ventricular interaction and inertial effects that accurately captures the physiological trends of a variety of disease states has been developed. However, the physiologically accurate open on pressure, close on flow valve law is computationally heavy to implemen...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2005.06.003
更新日期：2005-10-01 00:00:00
abstract：OBJECTIVES:Efficient clinical treatment processes is considered a key factor of medical quality control. Current IT solutions are far away from this perspective since they typically have difficulty supporting the variances occurring in clinical practices, and providing adequate flexible support of clinical processes. ...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2010.12.005
更新日期：2012-09-01 00:00:00
