Facilitating pharmacometric workflow with the metrumrg package for R.

Abstract:

:metrumrg is an R package that facilitates workflow for the discipline of pharmacometrics. Support is provided for data preparation, modeling, simulation, diagnostics, and reporting. Existing tools and techniques are emphasized where available; original solutions are provided for otherwise unmet needs. In particular, metrumrg implements an R interface for the NONMEM(®) modeling software, optionally run in a distributed computing environment. The paradigm allows start-to-finish analyses in a single scripting language. Emphasis on text-based formats promotes traceability of results.

authors

Bergsma TT,Knebel W,Fisher J,Gillespie WR,Riggs MM,Gibiansky L,Gastonguay MR

doi

10.1016/j.cmpb.2012.08.009

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

77-85

issue

1

eissn

0169-2607

issn

1872-7565

pii

S0169-2607(12)00191-5

journal_volume

109

pub_type

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