Abstract：
:Selecting appropriate ventilator settings decreases the risk of ventilator-induced lung injury. A decision support system (DSS) has been developed based on physiological models, which can advise on setting of tidal volume (Vt), respiratory frequency (f) and fraction of inspired oxygen (FiO2). The aim of this study is to assess the feasibility of the DSS by comparing its advice with the values used in clinical practice. Data from 20 patients following uncomplicated coronary artery bypass grafting (CABG) with cardiopulmonary bypass was used to test the DSS. Ventilator settings suggested by the DSS were compared to the settings selected by the clinician. When compared to the clinician the DSS suggested: lowering FiO2 (by median 7%, range 2-17%) at high SpO2 and increasing FiO2 (by median 2%, range 1-5%) at low SpO2; lowering ventilation volume (by median 0.57 l min(-1), range 0.2-1.1 l min(-1)) at high pHa and increasing ventilation volume (by median 0.4 l min(-1), range 0.1-0.9 l min(-1)) at low pHa. Suggested changes in ventilation volume were such that simulated values of PIP were < or = 22.9 cmH2O and respiratory frequency < or = 18 breaths min(-1). In all cases, computer suggested values of FiO2, Vt or f were consistent with maintaining sufficient oxygenation, normalising pH and obtaining low values of PIP.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Allerød C,Rees SE,Rasmussen BS,Karbing DS,Kjaergaard S,Thorgaard P,Andreassen Sdoi
10.1016/j.cmpb.2008.07.001subject
Has Abstractpub_date
2008-11-01 00:00:00pages
205-12issue
2eissn
0169-2607issn
1872-7565pii
S0169-2607(08)00179-Xjournal_volume
92pub_type
杂志文章abstract：:Cone beam computed tomography (CBCT) enables volumetric image reconstruction from 2D projection data and plays an important role in image guided radiation therapy (IGRT). Filtered back projection is still the most frequently used algorithm in applications. The algorithm discretizes the scanning process (forward projec...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2011.12.002
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Respiratory gating training is a common technique to increase patient proprioception, with the goal of (e.g.) minimizing the effects of organ motion during radiotherapy. In this work, we devise a system based on autoencoders for classification of regular, apnea and unconstrained breathing patte...
journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章,meta分析
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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更新日期：2016-05-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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更新日期：1993-05-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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doi：10.1016/j.cmpb.2005.08.002
更新日期：2005-12-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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pub_type： 杂志文章
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(88)90046-6
更新日期：1988-03-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(96)01742-n
更新日期：1996-07-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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更新日期：2016-10-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(94)90206-2
更新日期：1994-11-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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doi：10.1016/j.cmpb.2020.105320
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(93)90001-2
更新日期：1993-06-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2008.06.004
更新日期：2008-10-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/s0169-2607(02)00125-6
更新日期：2003-10-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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更新日期：2020-06-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2005.04.007
更新日期：2005-09-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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doi：10.1016/j.cmpb.2010.12.005
更新日期：2012-09-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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更新日期：1989-04-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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更新日期：2010-04-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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更新日期：2015-12-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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更新日期：2019-05-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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更新日期：2004-07-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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更新日期：2020-04-01 00:00:00
abstract：:For microdosimetric calculations event-by-event Monte Carlo (MC) methods are considered the most accurate. The main shortcoming of those methods is the extensive requirement for computational time. In this work we present an event-by-event MC code of low projectile energy electron and proton tracks for accelerated mic...
journal_title：Computer methods and programs in biomedicine
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doi：10.1016/j.cmpb.2013.09.009
更新日期：2014-01-01 00:00:00
