Abstract:
:DIMSUM, an acronym for DIMension of a SUM of exponentials, is a highly automated expert system for fitting multiexponential models of increasing dimension to time series data. Up to now, a researcher has needed an individual copy of DIMSUM on his or her own computer as well as support to learn how to use it. W3DIMSUM, a new implementation of DIMSUM, is web-based, new territory for interactive biomodeling, allowing interactive multiexponential model building and model discrimination over the Internet. The algorithms used are numerically intensive, so we have implemented a distributed system, with numerical processing done on our server. Only the user interface is run on the client machine, but users can load and save data and results on their machines, facilitated by our use of Java WebStart.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Harless C,Distefano JJ 3rddoi
10.1016/j.cmpb.2005.03.008subject
Has Abstractpub_date
2005-08-01 00:00:00pages
169-78issue
2eissn
0169-2607issn
1872-7565pii
S0169-2607(05)00082-9journal_volume
79pub_type
杂志文章abstract::The aim of segmentation of tumor regions in positron emission tomography (PET) is to provide more accurate measurements of tumor size and extension into adjacent structures, than is possible with visual assessment alone and hence improve patient management decisions. We propose a segmentation energy function for the g...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2012.10.009
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:To audit routine clinical practice in screening patients admitted to an accident and emergency department for deep venous thrombosis in the leg (DVT) and compare it with a computer algorithm. DESIGN:Retrospective study of case notes with data subsequently entered into a computer algorithm followed by a compa...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.105046
更新日期:2019-12-01 00:00:00
abstract::The Diabetes Advisory System (DIAS) is a model of human glucose metabolism which predicts hourly blood glucose concentrations and provides advice on insulin dose. Its ability to provide appropriate advice was assessed in 20 well-controlled IDDM patients (mean (SD) age 38 (11), duration 17 (9) years; HbA1 8.8 (0.9)%, r...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(98)00022-4
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Dataset imbalance is an important problem in neuroimaging. Imbalanced datasets would cause the performance degradation of a classifier by utilizing imbalanced learning, which tends to overfocus on the majority class. In this paper, we consider an imbalanced neuroimaging classification problem, ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105676
更新日期:2020-11-01 00:00:00
abstract::A Monte Carlo model of steady-state light transport in multi-layered tissues (MCML) has been coded in ANSI Standard C; therefore, the program can be used on various computers. Dynamic data allocation is used for MCML, hence the number of tissue layers and grid elements of the grid system can be varied by users at run ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(95)01640-f
更新日期:1995-07-01 00:00:00
abstract::Lumped parameter approaches for modelling the cardiovascular system typically have many parameters of which a significant percentage are often not identifiable from limited data sets. Hence, significant parts of the model are required to be simulated with little overall effect on the accuracy of data fitting, as well ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2010.01.002
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVES:Postoperative delirium is a common complication after major surgery among the elderly. Despite its potentially serious consequences, the complication often goes undetected and undiagnosed. In order to provide diagnosis support one could potentially exploit the information hidden in free text documents from e...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2017.09.014
更新日期:2017-12-01 00:00:00
abstract::This article presents a method of predictive simulation, patient-dependant, in real time of the abdominal organ positions during free breathing. The method, that considers both influence of the abdominal breathing and thoracic breathing, needs a tracking of the patient skin and a model of the patient-specific modifica...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2010.03.003
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Fatigue is an important cause of operational errors, and human errors are the main cause of accidents. This study is an exploratory study in China. Field tests were conducted on heart rate variability (HRV) parameters and physiological indicators of fatigue among miners in high-altitude, cold a...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105667
更新日期:2020-11-01 00:00:00
abstract::Advances in the area of computerized image analysis applied to mammography may have very important practical applications in automatically detecting asymmetries (masses, architectural distortions, etc.) between the two breasts. We have developed a fully automatic technique to detect the breast border and the nipple, t...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(96)01724-5
更新日期:1996-05-01 00:00:00
abstract::In recent years, mild cognitive impairment (MCI) has attracted significant attention as an indicator of high risk for Alzheimer's disease (AD), and the diagnosis of MCI can alert patient to carry out appropriate strategies to prevent AD. To avoid subjectivity in diagnosis, we propose an ontology driven decision suppor...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2013.12.023
更新日期:2014-03-01 00:00:00
abstract::Background and objective In-vivo MRI-guided drug delivery concept is a personalized technique towards cancer treatment. A major bottleneck of this method, is the weak magnetic response of nanoparticles. A crucial improvement is the usage of paramagnetic nanoparticles aggregates since they can easier manipulated in hum...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105778
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:T-wave alternans (TWA) is a fluctuation of the ST-T complex occurring on an every-other-beat basis of the surface electrocardiogram (ECG). It has been shown to be an informative risk stratifier for sudden cardiac death, though the lack of gold standard to benchmark detection methods has promote...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2017.04.005
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Diabetic disease is typically composed because of higher than normal blood sugar levels. Instead the production of insulin may be regarded insufficient. It has been noted in recent days that the percentage of diabetes-affected patients have grown to a larger extent throughout the world. Evident...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105659
更新日期:2020-11-01 00:00:00
abstract::In muscle cells, force development is controlled by Ca2+ ions, which are rapidly released from the sarcoplasmic reticulum (SR) during sarcolemmal depolarization. In addition to this synchronized spatially homogeneous calcium signal, localized quantal Ca2+ release events (sparks) have been recorded using laser scanning...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2004.06.004
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Complementary and alternative medicine techniques have shown their potential for the treatment and diagnosis of chronical diseases like diabetes, arthritis etc. On the same time digital image processing techniques for disease diagnosis is reliable and fastest growing field in biomedical. Propos...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2018.01.004
更新日期:2018-04-01 00:00:00
abstract::A flexible program for the IBM PC performing a number of calculations of relevance for the prescription of hemodialysis treatment has been developed. The program has a 'spreadsheet'-like user-friendly interface, and results may be presented graphically. The present implementation covers 89 algorithms/equations, all ba...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(90)90009-x
更新日期:1990-03-01 00:00:00
abstract::Open hashing is used to demonstrate the effectiveness of several hashing functions for the uniform distribution of biological records. The three types of database tested include (1) genetic nomenclature, mutation sites and strain names, (2) surnames extracted from literature files and (3) a set of 1000 numeric ASCII s...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(89)90164-8
更新日期:1989-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Several studies have evaluated the reproducibility of the Cobb angle for measuring the degree of scoliotic deformities from X-ray spine images, and proposed different geometric models for describing the spinal curvature. The ellipse was shown to be an adequate geometric form, but was not yet ap...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2018.04.015
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Orthodontic fixed appliance therapy involves alignment of teeth through the bracket and archwires. The archwire twist (torque) imparts significant forces inside the bracket slot in refining the teeth position at the end of treatment. The objective of this in- silico study was to evaluate the t...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105748
更新日期:2020-12-01 00:00:00
abstract::Accurate and fast approaches for automatic ECG data classification are vital for clinical diagnosis of heart disease. To this end, we propose a novel multistage algorithm that combines various procedures for dimensionality reduction, consensus clustering of randomized samples and fast supervised classification algorit...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2013.08.002
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:Over the years, medical image registration has been widely used in various fields. However, different application characteristics, such as scale, computational complexity, and optimization goals, can cause problems. Therefore, developing an optimization algorithm based on clustering calculation is crucial. ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105432
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In oral and maxillofacial surgery, conventional radiographic cephalometry is one of the standard auxiliary tools for diagnosis and surgical planning. While contemporary computer-assisted cephalometric systems and methodologies support cephalometric analysis, they tend neither to be practical no...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2016.03.014
更新日期:2016-07-01 00:00:00
abstract::In this study, the virtual reality (VR) proprioception rehabilitation system was developed for stroke patients to use proprioception feedback in upper limb rehabilitation by blocking visual feedback. To evaluate its therapeutic effect, 10 stroke patients (onset>3 month) trained proprioception feedback rehabilitation f...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2013.09.006
更新日期:2014-01-01 00:00:00
abstract::Fall detection, gait analysis and context recognition are examples of applications where capacitive accelerometers are widely used in health care. In most of the existing work, algorithms were developed for a specific platform and accelerometers were used without explicitly choosing a specific type. With this work we ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2011.10.009
更新日期:2012-05-01 00:00:00
abstract::We propose a specially optimized computer program for the user-independent calculation of the correlation dimension D and the largest Lyapunov exponent L of heart rate dynamics on the basis of only 1024 electrocardiographically recorded RR intervals (heartbeat intervals). The validity of our program was established by...
journal_title:Computer methods and programs in biomedicine
pub_type: 临床试验,杂志文章
doi:10.1016/0169-2607(95)01707-0
更新日期:1996-01-01 00:00:00
abstract::An iterative algorithm is given to correct for the zeroth and first order phase errors in NMR spectroscopy. A FORTRAN computer program is listed and two sample runs exemplified. No a priori knowledge of the existing phase errors is required. The parameters are optimised iteratively under the assumption that when the s...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(88)90078-8
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Accurate and fast vessel segmentation from liver slices remain challenging and important tasks for clinicians. The algorithms from the literature are slow and less accurate. We propose fast parallel gradient based seeded region growing for vessel segmentation. Seeded region growing is tedious w...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105430
更新日期:2020-08-01 00:00:00
abstract::As many structures of protein-DNA complexes have been known in the past years, several computational methods have been developed to predict DNA-binding sites in proteins. However, its inverse problem (i.e., predicting protein-binding sites in DNA) has received much less attention. One of the reasons is that the differ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2014.07.009
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Deep learning enables tremendous progress in medical image analysis. One driving force of this progress are open-source frameworks like TensorFlow and PyTorch. However, these frameworks rarely address issues specific to the domain of medical image analysis, such as 3-D data handling and distanc...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105796
更新日期:2021-01-01 00:00:00