Effects of atorvastatin on low-density lipoprotein cholesterol phenotype and C-reactive protein levels in patients undergoing long-term dialysis.

abstract：:A 64-year-old woman receiving intravenous chemotherapy for stage IIIB non-small cell lung cancer experienced acute arterial thrombosis of the distal radial and entire ulnar arteries with subsequent arterial occlusion of the right popliteal artery. Two separate arterial occlusions occurred after administration of cispl...

journal_title：Pharmacotherapy

authors： Cool RM,Herrington JD,Wong L

更新日期：2002-09-01 00:00:00

abstract：:Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a rare, complex, idiosyncratic drug reaction that can be fatal. Systemic symptoms include lymphadenopathy, hepatic failure, and possibly renal failure. The syndrome has been primarily associated with anticonvulsants, whereas antimicrobials are less ...

journal_title：Pharmacotherapy

authors： Miller Quidley A,Bookstaver PB,Gainey AB,Gainey MD

更新日期：2012-12-01 00:00:00

abstract：:We attempted to determine physician prescribing patterns of angiotensin-converting enzyme (ACE) inhibitors in patients who experienced a myocardial infarction, stratified by left ventricular function. We retrospectively reviewed drug therapy at discharge in 534 patients to assess prescription of ACE inhibitor therapy,...

journal_title：Pharmacotherapy

authors： Luzier AB,Navsarikar A,Wilson MF,Ashai K,Forrest A

更新日期：1999-05-01 00:00:00

abstract：:High-performance capillary electrophoresis (HPCE) is a new separation technique that is applied in the pharmaceutical sciences. Separations by HPCE occur in a narrow-bore capillary under the influence of an applied electrical field. Components of the sample matrix are separated and migrate at different rates based on ...

journal_title：Pharmacotherapy

authors： Brunner LJ,DiPiro JT,Feldman S

更新日期：1995-01-01 00:00:00

abstract：:Cyclosporine can be given intravenously or orally, as a solution or soft gelatin capsule. Because of the drug's poor water solubility, ethoxylated plant fats and ethanol are added to the commercially available dosage forms. ...

journal_title：Pharmacotherapy

authors： Yee GC

更新日期：1991-01-01 00:00:00

abstract：:Methemoglobin, a form of hemoglobin that does not bind oxygen, is produced when iron in red blood cells is oxidized from the ferrous state to the ferric state. Methemoglobinemia develops in the presence of oxidizing agents, such as benzocaine-containing topical anesthetic sprays, and it is characterized by cyanosis. I...

journal_title：Pharmacotherapy

authors： Throm MJ,Stevens MD,Hansen C

更新日期：2007-08-01 00:00:00

abstract：:Diazepam is frequently the subject of review by various agencies and institutions charged with determining whether or not to substitute another, more economical drug--in most instances, chlordiazepoxide. A review of the comparative literature has shown that, on clinical and pharmacokinetic grounds, chlordiazepoxide is...

journal_title：Pharmacotherapy

authors： Baskin SI,Esdale A

更新日期：1982-03-01 00:00:00

abstract：:Ceftazidime, a beta-lactamase-stable, third-generation cephalosporin, is widely used for the treatment of serious gram-negative infections. Neurotoxicity has rarely been associated with the drug; however, two of our patients developed ceftazidime-induced neurotoxicity that produced confusion, disorientation, agitation...

journal_title：Pharmacotherapy

authors： Slaker RA,Danielson B

更新日期：1991-01-01 00:00:00

abstract：STUDY OBJECTIVES:To examine glycosylated hemoglobin (A1C) values longitudinally in patients who newly started metformin, sulfonylurea, or thiazolidinedione monotherapy; in a subset of patients whose A1C values were 7% or greater before starting therapy (baseline) and who achieved A1C goal (A1C < 7%) during therapy, rat...

journal_title：Pharmacotherapy

authors： Riedel AA,Heien H,Wogen J,Plauschinat CA

更新日期：2007-08-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the effectiveness and safety of enoxaparin therapy in a neonatal intensive care unit (NICU). DESIGN:Retrospective chart review. SETTING:Level III NICU in a Canadian academic center. PATIENTS:All neonates treated with enoxaparin while in the NICU between January 1, 1998, and June 1, 2006. ...

journal_title：Pharmacotherapy

authors： Malowany JI,Knoppert DC,Chan AK,Pepelassis D,Lee DS

更新日期：2007-09-01 00:00:00

abstract：:Endothelin (ET)-1 is an endothelium-derived peptide with potent vasoconstrictor and proliferative properties. The ET system is activated in several cardiovascular disease states associated with functional and structural vascular changes, including hypertension and heart failure. The two ET receptor subtypes are known ...

journal_title：Pharmacotherapy

authors： Ergul A

更新日期：2002-01-01 00:00:00

abstract：STUDY OBJECTIVE:To compare the efficacy of amlodipine and valsartan in African-American patients with hypertension using ambulatory blood pressure monitoring (ABPM). DESIGN:Prospective, randomized, double-blind, crossover comparison study. SETTING:University-affiliated cardiac center clinic. PATIENTS:Twenty African-...

journal_title：Pharmacotherapy

authors： Maciejewski S,Mohiuddin SM,Packard KA,Mooss AN,Reyes AP,Aryana A,Hilleman DE

更新日期：2006-07-01 00:00:00

abstract：STUDY OBJECTIVE:Evaluate dabigatran adverse event reports with a reported bleeding event and/or reported fatal outcome compared with warfarin. DESIGN:Retrospective analysis of the FDA Adverse Event Reporting System (FAERS) database. MEASUREMENTS AND MAIN RESULTS:We identified reports from October 1, 2010, through Dec...

journal_title：Pharmacotherapy

authors： McConeghy KW,Bress A,Qato DM,Wing C,Nutescu EA

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:As one of the most accessible health care professionals, pharmacists are in an ideal position to provide tobacco-cessation and prevention services. Although there is growing interest in expanding the pharmacist's role in tobacco treatment, few published studies have assessed the efficacy or effectiveness of ...

journal_title：Pharmacotherapy

authors： Dent LA,Harris KJ,Noonan CW

更新日期：2007-07-01 00:00:00

abstract：:With the emergence of new anticoagulants, clinicians need a thorough understanding of coagulation assays. Various laboratory assays exist to measure the effectiveness of anticoagulants. Coagulation assays are the primary method for measuring the effectiveness of anticoagulants; therefore, a comprehensive understanding...

journal_title：Pharmacotherapy

authors： Peters GL,Erwin PB,Pitlick MK,Stacy ZA

更新日期：2013-11-01 00:00:00

abstract：:Our objective was to describe the implementation and clinical outcomes of an employer-sponsored, pharmacist-provided medication therapy management (MTM) program for health plan beneficiaries with diabetes mellitus and/or hypertension. We conducted a single-center retrospective medical record review. The setting was a ...

journal_title：Pharmacotherapy

authors： Theising KM,Fritschle TL,Scholfield AM,Hicks EL,Schymik ML

更新日期：2015-11-01 00:00:00

abstract：:Aztreonam is the first monobactam available for use in this country. A parenteral antibiotic, its antibacterial spectrum is limited to gram-negative aerobic pathogens. The drug's pharmacologic, pharmacokinetic, and toxicologic properties are reviewed. Based on early experience in pediatric patients, certain recommenda...

journal_title：Pharmacotherapy

authors： Bosso JA,Black PG

更新日期：1991-01-01 00:00:00

abstract：:Major depression afflicts a significant percentage of the population, and optimum therapy is often limited by the poor tolerability and lethality in overdose of the tricyclic antidepressants. The selective serotonin reuptake inhibitors (SSRIs) fluoxetine, sertraline, and, more recently, paroxetine are viewed as welcom...

journal_title：Pharmacotherapy

authors： Nemeroff CB

更新日期：1994-03-01 00:00:00

abstract：STUDY OBJECTIVES:To determine if low-dose lovastatin in combination with niacin causes a greater percentage reduction in low-density lipoprotein (LDL) cholesterol than lovastatin alone, and to determine if the combination increases the risk of serious adverse effects. design. Prospective, randomized, open-label, clinic...

journal_title：Pharmacotherapy

authors： Gardner SF,Schneider EF,Granberry MC,Carter IR

更新日期：1996-05-01 00:00:00

abstract：STUDY OBJECTIVES:To compare the effectiveness of bivalirudin and argatroban in achieving anticoagulation goals and to compare clinical outcomes assessing the safety and efficacy in patients with known or suspected heparin-induced thrombocytopenia (HIT). DESIGN:Single-center, retrospective analysis. SETTING:Large tert...

journal_title：Pharmacotherapy

authors： Skrupky LP,Smith JR,Deal EN,Arnold H,Hollands JM,Martinez EJ,Micek ST

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Historically, there is perceived pressure to achieve therapeutic levels of tacrolimus quickly after heart transplant (HT). We evaluated the association between time within therapeutic tacrolimus range and time to therapeutic trough and rejection in the 30 days following HT. METHODS:This is a single-center r...

journal_title：Pharmacotherapy

authors： Baker WL,Steiger S,Martin S,Patel N,Radojevic J,Darsaklis K,O'Bara L,Kutzler H,Dougherty J,Feingold A,Hammond J,Fusco D,Gluck JA

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:As tenofovir disoproxil fumarate substantially increases plasma concentrations of didanosine in patients with human immunodeficiency virus-1 infection, we sought to determine whether tenofovir and didanosine showed a similar intracellular interaction in human peripheral blood mononuclear cells (PBMCs). DESIG...

journal_title：Pharmacotherapy

authors： Robbins BL,Wilcox CK,Fridland A,Rodman JH

更新日期：2003-06-01 00:00:00

abstract：:Warfarin is a commonly used oral anticoagulant that is usually initiated after the definitive diagnosis of a certain thromboembolic disorder or disease. Warfarin therapy will usually be prescribed for 6-12 weeks or more, and some patients may continue therapy throughout life, depending on the type of thromboembolic di...

journal_title：Pharmacotherapy

authors： Yamreudeewong W,Johnson JV,Cassidy TG,Berg JT

更新日期：1996-11-01 00:00:00

abstract：:Patients with various rheumatologic and inflammatory disease states commonly require drugs known to decrease the inflammatory or autoimmune response for adequate control of their condition. Such drugs include nonsteroidal antiinflammatory drugs (NSAIDs), cyclooxygenase (COX)-2 inhibitors, corticosteroids, disease-modi...

journal_title：Pharmacotherapy

authors： Busti AJ,Hooper JS,Amaya CJ,Kazi S

更新日期：2005-11-01 00:00:00

abstract：:Surgical hemostasis may be achieved by using a number of physical, chemical, or biologic methods. One such method is with topical thrombin; however, one member of that class of drugs, bovine-derived thrombin, is associated with potentially serious consequences such as development of immune-mediated coagulopathy. This ...

journal_title：Pharmacotherapy

authors： Naoum JJ

更新日期：2009-07-01 00:00:00

abstract：STUDY OBJECTIVE:To establish the clinical equivalence (noninferiority) of one tablet containing abacavir 300 mg-lamivudine 150 mg-zidovudine 300 mg (Trizivir) versus a tablet containing lamivudine 150 mg-zidovudine 300 mg (Combivir) given with one abacavir (ABC) 300-mg tablet, administered twice/day, in antiretroviral-...

journal_title：Pharmacotherapy

authors： Fischl MA,Burnside AE Jr,Farthing CE,Thompson MA,Bellos NC,Williams VC,Kauf TL,Wannamaker PG,Shaefer MS,ESS40005 Study Team.

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:Assess the effects of linezolid on hematologic outcomes in newly diagnosed patients with acute myeloid leukemia (AML) following induction chemotherapy. DESIGN:Single-center, retrospective, observational, cohort study. SETTING:Large, tertiary care academic medical center. PATIENTS:A total of 225 patients ≥ ...

journal_title：Pharmacotherapy

authors： Nedved AN,DeFrates SR,Hladnik LM,Stockerl-Goldstein KE

更新日期：2016-10-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the success of an initial tobramycin dosing regimen to achieve target peak and trough concentrations in adult patients with pulmonary exacerbations of cystic fibrosis (CF). DESIGN:Retrospective single-center medical record review. SETTING:Large tertiary care academic medical center. PATIE...

journal_title：Pharmacotherapy

authors： Staubes BA,Metzger NL,Walker SD,Peasah SK

更新日期：2016-06-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the effects of topical atorvastatin on the healing process of pressure ulcers in critically ill patients. DESIGN:Randomized, double-blind, placebo-controlled clinical trial. SETTING:Medical-surgical intensive care unit of a university-affiliated teaching hospital in Tehran, Iran. PATIENTS...

journal_title：Pharmacotherapy

authors： Farsaei S,Khalili H,Farboud ES,Karimzadeh I,Beigmohammadi MT

更新日期：2014-01-01 00:00:00

abstract：:Infections caused by yeasts and molds continue to be associated with high rates of morbidity and mortality in both immunocompromised and immunocompetent patients. Many antifungal drugs have been developed over the past 15 years to aid in the management of these infections. However, treatment is still not optimal, as t...

journal_title：Pharmacotherapy

authors： Mohr J,Johnson M,Cooper T,Lewis JS,Ostrosky-Zeichner L

更新日期：2008-05-01 00:00:00