Abstract:
:Ceftazidime, a beta-lactamase-stable, third-generation cephalosporin, is widely used for the treatment of serious gram-negative infections. Neurotoxicity has rarely been associated with the drug; however, two of our patients developed ceftazidime-induced neurotoxicity that produced confusion, disorientation, agitation, generalized weakness, and myoclonus. In both patients these symptoms cleared with either discontinuation or reduction of the dosage of ceftazidime. This emphasizes the importance of adjusting the dosage of ceftazidime in patients with renal insufficiency.
journal_name
Pharmacotherapyjournal_title
Pharmacotherapyauthors
Slaker RA,Danielson Bsubject
Has Abstractpub_date
1991-01-01 00:00:00pages
351-2issue
4eissn
0277-0008issn
1875-9114journal_volume
11pub_type
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