Dosage forms of cyclosporine.

Abstract:

:Cyclosporine can be given intravenously or orally, as a solution or soft gelatin capsule. Because of the drug's poor water solubility, ethoxylated plant fats and ethanol are added to the commercially available dosage forms.

journal_name

Pharmacotherapy

journal_title

Pharmacotherapy

authors

Yee GC

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

149S-152S

issue

6

eissn

0277-0008

issn

1875-9114

journal_volume

11

pub_type

杂志文章,评审
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    abstract::A hiccup is a myoclonic jerk of the diaphragm, and cases of hiccups may last for more than 48 hours (persistent hiccups) or even more than 2 months (intractable hiccups). Current pharmacologic treatment of persistent or intractable hiccups mainly includes antidopaminergic drugs. We describe the case of a 60-year-old m...

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    authors: Naro A,Bramanti P,Calabrò RS

    更新日期:2014-12-01 00:00:00

  • Current guidelines for treatment of heart failure: 2006 update.

    abstract::Several pivotal clinical trials have generated new knowledge regarding drug therapy for heart failure. Thus, the Heart Failure Society of America (HFSA) and the American College of Cardiology-American Heart Association (ACC-AHA) guidelines were updated in 2006 and 2005, respectively. We review the evidence from these ...

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    authors: Uddin N,Patterson JH

    更新日期:2007-04-01 00:00:00

  • Statin-associated peripheral neuropathy: review of the literature.

    abstract::Various pharmacologic agents are available for the treatment of hypercholesterolemia, including 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, commonly referred to as statins, which offer favorable lipid-lowering effects and reductions in morbidity and mortality. Statins are usually better toler...

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    更新日期:2004-09-01 00:00:00

  • Discrepancies in identification of bleeding events after percutaneous coronary intervention.

    abstract:STUDY OBJECTIVE:To evaluate the level of agreement between two sets of criteria, the Thrombolysis in Myocardial Infarction (TIMI) criteria and investigator-developed criteria, for identifying bleeding events in patients who had undergone a percutaneous coronary intervention (PCI) and to measure length of hospital stay ...

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    doi:10.1592/phco.27.1.36

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    更新日期:2007-01-01 00:00:00

  • A double-blind, placebo-controlled evaluation of intranasal metoclopramide in the prevention of postoperative nausea and vomiting.

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    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Wagner BK,Berman SL,Devitt PA,Halvorsen MB,O'Hara DA

    更新日期:1996-11-01 00:00:00

  • Effects of carbamazepine on cyclosporine metabolism in pediatric renal transplant recipients.

    abstract::This study documents a pharmacokinetic interaction between carbamazepine and cyclosporine (CsA) in pediatric renal transplant recipients. Noncompartmental steady-state CsA pharmacokinetics were determined in three pediatric renal transplant recipients who were receiving both CsA and carbamazepine as long-term therapy ...

    journal_title:Pharmacotherapy

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    doi:

    authors: Cooney GF,Mochon M,Kaiser B,Dunn SP,Goldsmith B

    更新日期:1995-05-01 00:00:00

  • The clinical pharmacology and use of paroxetine, a new selective serotonin reuptake inhibitor.

    abstract::Major depression afflicts a significant percentage of the population, and optimum therapy is often limited by the poor tolerability and lethality in overdose of the tricyclic antidepressants. The selective serotonin reuptake inhibitors (SSRIs) fluoxetine, sertraline, and, more recently, paroxetine are viewed as welcom...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章,评审

    doi:

    authors: Nemeroff CB

    更新日期:1994-03-01 00:00:00

  • The pharmacokinetics and pharmacodynamics of fludarabine in rheumatoid arthritis.

    abstract:STUDY OBJECTIVE:To describe the pharmacokinetics and pharmacodynamics of fludarabine in patients with rheumatoid arthritis (RA). DESIGN:Open-label, staggered trial conducted in conjunction with a phase I-II clinical trial. SETTING:Government research hospital. PATIENTS:Twenty-six patients with refractory RA. INTERV...

    journal_title:Pharmacotherapy

    pub_type: 临床试验,杂志文章

    doi:

    authors: Knebel W,Davis JC Jr,Sanders WD,Fessler B,Yarboro C,Pucino F,Boumpas DT

    更新日期:1998-11-01 00:00:00

  • Metabolism of tenofovir and didanosine in quiescent or stimulated human peripheral blood mononuclear cells.

    abstract:OBJECTIVE:As tenofovir disoproxil fumarate substantially increases plasma concentrations of didanosine in patients with human immunodeficiency virus-1 infection, we sought to determine whether tenofovir and didanosine showed a similar intracellular interaction in human peripheral blood mononuclear cells (PBMCs). DESIG...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章

    doi:10.1592/phco.23.6.695.32189

    authors: Robbins BL,Wilcox CK,Fridland A,Rodman JH

    更新日期:2003-06-01 00:00:00

  • Evaluation of the Effectiveness of Two Morphine Protocols to Treat Neonatal Abstinence Syndrome in a Level II Nursery in a Community Hospital.

    abstract::The authors sought to evaluate the impact on length of hospital stay and treatment duration of morphine after implementation of a change in the institutional protocol for managing neonatal abstinence syndrome (NAS) in an effort to improve patient outcomes. A single-center, retrospective chart review was conducted at a...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章

    doi:10.1002/phar.1966

    authors: DeAtley HN,Burton A,Fraley MD,Haltom J

    更新日期:2017-07-01 00:00:00

  • Pharmacokinetics of intravenous trovafloxacin in critically ill adults.

    abstract::The pharmacokinetic disposition of numerous antimicrobial agents is altered in critically ill patients. Pharmacokinetics of trovafloxacin, a fluoroquinolone indicated specifically for severe, life-threatening infections in the intensive care unit, have not been well studied in this population. We characterized the pha...

    journal_title:Pharmacotherapy

    pub_type: 临床试验,杂志文章,多中心研究

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    更新日期:2000-04-01 00:00:00

  • Prevention of Clostridium difficile Infection in Critically Ill Adults.

    abstract::The incidence and severity of Clostridium difficile infection (CDI) remain high across intensive care units in the United States despite national efforts to decrease this escalating health care burden. Most published literature and guidelines address treatment rather than prevention, yet this approach may be too downs...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章,评审

    doi:10.1002/phar.2200

    authors: Leedahl DD,Personett HA,Nagpal A,Barreto EF

    更新日期:2019-03-01 00:00:00

  • N-acetylcysteine for prevention of radiographic contrast material-induced nephropathy: is the intravenous route best?

    abstract::Use of oral N-acetylcysteine for preventing radiographic contrast material-induced nephropathy (RCIN) has become widespread, despite conflicting results from clinical trials and meta-analyses. The variability in study results may reflect differences in baseline risks in study patients, hydration regimens, choice of co...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章,评审

    doi:10.1592/phco.2005.25.8.1095

    authors: Shalansky SJ,Vu T,Pate GE,Levin A,Humphries KH,Webb JG

    更新日期:2005-08-01 00:00:00

  • Effects of atorvastatin on low-density lipoprotein cholesterol phenotype and C-reactive protein levels in patients undergoing long-term dialysis.

    abstract:STUDY OBJECTIVES:To determine the effects of atorvastatin on low-density lipoprotein cholesterol (LDL) particle size and C-reactive protein (CRP) concentrations in patients undergoing long-term hemodialysis. Another objective was to compare the effects of atorvastatin on lipoprotein profiles as determined by direct ver...

    journal_title:Pharmacotherapy

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1592/phco.25.3.335.61599

    authors: Dornbrook-Lavender KA,Joy MS,Denu-Ciocca CJ,Chin H,Hogan SL,Pieper JA

    更新日期:2005-03-01 00:00:00

  • Reduction in warfarin adverse events requiring patient hospitalization after implementation of a pharmacist-managed anticoagulation service.

    abstract:STUDY OBJECTIVE:To compare adverse events related to anticoagulation in patients assigned to a pharmacist-managed anticoagulation service versus those receiving usual care. DESIGN:Retrospective cohort analysis. SETTING:Three hundred-bed community hospital. PATIENTS:Four hundred twenty patients referred for anticoagu...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章

    doi:10.1592/phco.25.5.685.63582

    authors: Locke C,Ravnan SL,Patel R,Uchizono JA

    更新日期:2005-05-01 00:00:00

  • Warfarin and royal jelly interaction.

    abstract::An 87-year-old African-American man came to the internal medicine clinic for a routine anticoagulation management visit. He had no complaints. His medical history was significant for stage IV-A follicular non-Hodgkin's lymphoma, atrial fibrillation, and hypertension. His long-term drug therapy consisted of warfarin, f...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章

    doi:10.1592/phco.26.4.583

    authors: Lee NJ,Fermo JD

    更新日期:2006-04-01 00:00:00

  • Key articles and guidelines in the management of hypertension: 2008 update.

    abstract::Hypertension remains a major risk factor for cardiovascular disease. The optimal choice of pharmacologic and nonpharmacologic treatment regimens is based on a plethora of published literature. This compilation is the initial update to the Key Articles and Guidelines in the Management of Hypertension authored by member...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章

    doi:10.1592/phco.28.8.1041

    authors: Gaffney SM,de Denus S,Olson KL,Ripley TL,Robinette B,Summers KM,Spencer AP

    更新日期:2008-08-01 00:00:00

  • Low-dose botulinum toxin type A for the treatment of refractory piriformis syndrome.

    abstract:STUDY OBJECTIVES:To evaluate the efficacy of a single, low-dose injection of botulinum toxin type A in relieving pain in Korean patients with piriformis syndrome resistant to conventional therapy, and to assess the drug's influence on these patients' quality of life. DESIGN:Prospective, single-site, open-label trial. ...

    journal_title:Pharmacotherapy

    pub_type: 临床试验,杂志文章

    doi:10.1592/phco.27.5.657

    authors: Yoon SJ,Ho J,Kang HY,Lee SH,Kim KI,Shin WG,Oh JM

    更新日期:2007-05-01 00:00:00

  • Improving pharmacotherapy after myocardial infarction by group academic detailing using feedback data on a patient level.

    abstract:STUDY OBJECTIVE:To develop and evaluate a peer review group (PRG) meeting using feedback data on a patient level to improve the quality of drug therapy for prevention of recurrent myocardial infarction. DESIGN:Prospective follow-up study. DATA SOURCE:General practitioners' computerized patients records (intervention ...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章

    doi:10.1592/phco.26.2.254

    authors: van der Elst ME,Bouvy ML,de Blaey CJ,de Boer A

    更新日期:2006-02-01 00:00:00

  • Pharmacokinetics and dose-proportionality of oxymorphone extended release and its metabolites: results of a randomized crossover study.

    abstract:STUDY OBJECTIVE:To evaluate the pharmacokinetics and dose-proportionality of four dose strengths (5, 10, 20, and 40 mg) of oxymorphone extended release (ER) under both single-dose and steady-state conditions. DESIGN:Randomized, three-period, four-sequence, crossover study. SETTING:Bioavailability clinic. SUBJECTS:Tw...

    journal_title:Pharmacotherapy

    pub_type: 临床试验,杂志文章,随机对照试验

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    更新日期:2004-04-01 00:00:00

  • The future of cell therapy.

    abstract::Peripheral blood has replaced bone marrow as a source of hematopoietic stem cells for autologous rescue after high-dose chemotherapy. Patients who receive peripheral blood stem cell (PBSC) transplants experience rapid and sustained hematopoietic reconstitution. As a result, transplant-related mortality is now less tha...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章

    doi:

    authors: Yee GC

    更新日期:1996-05-01 00:00:00

  • Colistin: understanding and applying recent pharmacokinetic advances.

    abstract::Colistin, the most widely used polymyxin antibiotic, was originally introduced in the late 1950s before the establishment of the present-day drug approval process. Originally shelved due to toxicity concerns, colistin, in the form of its inactive prodrug colistin methanesulfonate, has undergone a renaissance in the pa...

    journal_title:Pharmacotherapy

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    更新日期:2015-01-01 00:00:00

  • Acute hepatic failure associated with oral minocycline: a case report.

    abstract::A 39-year-old woman was evaluated for possible liver transplantation due to rapidly developing hepatic failure 4 weeks after initiation of oral minocycline 100 mg twice a day for the treatment of acne. The patient developed a maculopapular rash, malaise, fever, nausea, and vomiting 2 weeks prior to admission to the ho...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章

    doi:

    authors: Min DI,Burke PA,Lewis WD,Jenkins RL

    更新日期:1992-01-01 00:00:00

  • Acute Graft-versus-Host Disease: Emerging Insights and Updates into Detection, Prevention, and Treatment.

    abstract::Acute graft-versus-host disease remains a devastating complication following hematopoietic cell transplantation, resulting in increased morbidity and mortality. Vast research efforts continue to refine or develop new means of prediction, assessment, prevention, and treatment of this syndrome. Recent updates in acute g...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章,评审

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  • Pharmacodynamic Effects of Low-Dose Pioglitazone in Patients with the Metabolic Syndrome without Diabetes Mellitus.

    abstract:STUDY OBJECTIVE:To determine the effects of low-dose pioglitazone on plasma adipocyte-derived cytokines, high-sensitivity C-reactive protein (hs-CRP), and components of the metabolic syndrome in adults with the metabolic syndrome without diabetes mellitus. DESIGN:Prospective, randomized, double-blind, placebo-controll...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/phar.1713

    authors: Vu A,Kosmiski LA,Beitelshees AL,Prigeon R,Sidhom MS,Bredbeck B,Predhomme J,Deininger KM,Aquilante CL

    更新日期:2016-03-01 00:00:00

  • Role of intraarterial therapy for cerebral vasospasm secondary to aneurysmal subarachnoid hemorrhage.

    abstract::Aneurysmal subarachnoid hemorrhage (SAH) accounts for a significant percentage of morbidity and mortality among patients admitted to neurosurgical centers throughout the world. Even for individuals surviving beyond the initial presentation and intervention for aneurysmal SAH, the occurrence of cerebral vasospasm has t...

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    pub_type: 杂志文章,评审

    doi:10.1592/phco.30.4.405

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  • Issues in developing an outpatient deep venous thrombosis treatment program: university hospital experience.

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    journal_title:Pharmacotherapy

    pub_type: 杂志文章

    doi:

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    更新日期:1998-11-01 00:00:00

  • Urogenital atrophy: prevention and treatment.

    abstract::Fifteen percent of premenopausal women, 10-40% of postmenopausal women, and 10-25% of women receiving systemic hormone therapy experience urogenital atrophy. The most common symptoms are dryness, burning, pruritus, irritation, and dyspareunia. Estrogen loss, drugs, and chemical sensitivities are causes. Estrogen or ho...

    journal_title:Pharmacotherapy

    pub_type: 杂志文章,评审

    doi:10.1592/phco.21.5.464.34486

    authors: Willhite LA,O'Connell MB

    更新日期:2001-04-01 00:00:00

  • Cholesterol and glycemic effects of Niaspan in patients with type 2 diabetes.

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    pub_type: 杂志文章

    doi:10.1592/phco.21.20.1473.34481

    authors: Kane MP,Hamilton RA,Addesse E,Busch RS,Bakst G

    更新日期:2001-12-01 00:00:00

  • Comparing the bispectral index and suppression ratio with burst suppression of the electroencephalogram during pentobarbital infusions in adult intensive care patients.

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