Abstract：
:Snoring and obstructive sleep apnoea/hypopnoea syndrome (OSAHS) are often treated with mandibular repositioning splints (MRS), but the efficacy and satisfaction of them has not been comprehensively addressed. A survey on the use of and satisfaction with MRS was posted to 177 patients referred by a hospital orthodontic department for custom-fitting of a MRS. Data were analysed using non-parametric techniques. The response rate was 81% (n=144). Responders (30F, 114M) had mean (SD) age of 51 (11) years, apnoea+hypopnoea index (AHI) of 24 (21) per hr and Epworth Score of 10 (5) at diagnosis, and had been supplied with their MRS a median 7 (IQR 5-11) months previously. Fifty of the 144 patients (35%) had been offered continuous positive airway pressure (CPAP) treatment but had declined or abandoned this. Self-reported MRS use was 5 (2) h/night, with 74 of the 144 patients (51%) continuing to use MRS at least occasionally at a median 7 months after fitting. Survival analysis showed 12% still using MRS at 12 months. Epworth score fell slightly with MRS therapy [-2.4 (3.5); P=0.005] and 7 daytime and 2 nocturnal symptoms improved in MRS users (all P<0.05). Marital satisfaction did not change with MRS. Problems preventing MRS use in 70 non-users included: non-retention (n=12), sore mouth (n=13) or jaw (n=7), difficulties falling asleep (n=10) or breathing (n=7), excessive salivation (n=4), dental damage (n=4) and other problems (n=3). Continued use of MRS therapy was associated with a higher number of teeth, low marital satisfaction perceived by partners and greater improvement in symptoms reported by patients and partners. Continuance with MRS may be low and linked to tolerance problems.
journal_name
Respir Medjournal_title
Respiratory medicineauthors
Izci B,McDonald JP,Coleman EL,Mackay TW,Douglas NJ,Engleman HMdoi
10.1016/j.rmed.2004.07.007subject
Has Abstractpub_date
2005-03-01 00:00:00pages
337-46issue
3eissn
0954-6111issn
1532-3064pii
S0954-6111(04)00279-3journal_volume
99pub_type
杂志文章abstract：:The principals of rehabilitation medicine are to prevent muscle atrophy and improve mobility. Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with muscle atrophy and yet many patients do not undergo pulmonary rehabilitation until they have been in stable health for some time. We investigat...
journal_title：Respiratory medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.rmed.2005.02.033
更新日期：2005-10-01 00:00:00
abstract：BACKGROUND:Changes in management of COPD in primary care were studied following a training exercise among Spanish general practitioners (GPs). The exercise involved dissemination of the Spanish Society for Pulmonology and Thoracic Surgery (SEPAR) guidelines. The use of a portable device to perform spirometry tests was ...
journal_title：Respiratory medicine
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.rmed.2009.08.003
更新日期：2010-01-01 00:00:00
abstract：INTRODUCTION:The duration of bronchodilator action of the long-acting beta agonist salmeterol when administered in the evening has not been investigated. In this study we have investigated whether a single evening dose of salmeterol, administered from the combination salmeterol/fluticasone (SFC) Accuhaler significantly...
journal_title：Respiratory medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.rmed.2004.10.001
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVE:This study investigated the accuracy of impulse oscillometry (IOS) combined with fractional exhaled nitric oxide (FeNO) to assess asthma control among preschool children. METHODS:A total of 79 preschool children(3-6 year old) with asthma and 25 healthy preschool children who visited a paediatrician were enro...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2018.10.009
更新日期：2018-12-01 00:00:00
abstract：:Fifty-four members of two families were studied, nine of whom had familial spontaneous pneumothorax. The disease was inherited by autosomal-dominant type, with incomplete penetration and (or) variable expression. Five patients underwent bullectomy and parietal pleurectomy simultaneously on both sides via median sterno...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/s0954-6111(08)80011-x
更新日期：1990-03-01 00:00:00
abstract：BACKGROUND:An ongoing outbreak of coronavirus disease 2019 (COVID-19) has spread around the world. It is debatable whether asymptomatic COVID-19 virus carriers are contagious. We report here a case of the asymptomatic patient and present clinical characteristics of 455 contacts, which aims to study the infectivity of a...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2020.106026
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:Small fiber neuropathy commonly affects patients with sarcoidosis and is often refractory to standard immunosuppressive therapies used for systemic disease. The clinical features of sarcoidosis-associated small fiber neuropathy (SSFN) and its response to medical therapy have not been described in a large popu...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2017.03.011
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:Although the prevalence of chronic obstructive pulmonary disease (COPD) increases with age, no specific therapeutic approaches are available till date for the elderly population. AIM:To assess the efficacy and safety of once-daily indacaterol 150 and 300 μg in elderly patients with moderate to severe COPD. ...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2017.05.010
更新日期：2017-07-01 00:00:00
abstract：INTRODUCTION:Primary ciliary dyskinesia (PCD) is a rare genetically heterogeneous disorder of motile cilia, which leads to recurrent and chronic airway infections. Detailed information about infection causing pathogens is scarce. With this study, we aimed to determine the prevalence and susceptibility of the most commo...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2019.08.009
更新日期：2019-09-01 00:00:00
abstract：PURPOSE:We conducted a randomised controlled trial to assess the effects of daily breathing pattern changes to stable patients with COPD excluding the confounding factors of inspiratory muscle mobilization, by ensuring the load intensities of two inspiratory training devices were equal. PATIENTS AND METHODS:Sixty pati...
journal_title：Respiratory medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.rmed.2017.10.001
更新日期：2017-11-01 00:00:00
abstract：RATIONALE:Asthma is a heterogeneous disease, and a great majority of pediatric patients with asthma demonstrate atopic characteristics and develop a Th2 type cytokine response. Nonatopic asthma, on the other hand, is seen more rarely. METHODS:In this study, levels of IL-5, IL-8 and MMP-9 were measured in exhaled breat...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2015.04.004
更新日期：2015-06-01 00:00:00
abstract：:Limited knowledge exists about development of bronchial hyperresponsiveness (BHR) through adolescence. We aimed to assess changes in and risk factors for BHR in adolescence. From a Norwegian birth cohort 517 subjects underwent clinical examinations, structured interviews and methacholine challenges at age 10 and 16. B...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2011.09.013
更新日期：2012-02-01 00:00:00
abstract：RATIONALE:Exercise-induced bronchoconstriction (EIB) increases in cold and dry air and decreases in humid air in subjects with asthma. Few reports have reported on the effect of humid environment upon exercise capacity in subjects with EIB. OBJECTIVE:The primary aim of the present study was to examine the effect of ch...
journal_title：Respiratory medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.rmed.2005.12.001
更新日期：2006-09-01 00:00:00
abstract：:The oxygen cost diagram (OCD) is a simple scale for quantifying a patient's evaluation of his tolerance to exercise frequently used in clinical trials; it has been shown to be well correlated with objective measures of capacity of ambulation such as the 6 min walk test (6' W). This study aimed to determine whether the...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/s0954-6111(99)90266-4
更新日期：1999-11-01 00:00:00
abstract：:A double-blind, randomized crossover study in 28 asthmatic patients assessed the relative therapeutic index for inhaled formoterol and salbutamol. Pre-drug administration FEV1 (mean 2.08 l) was 49-93% of predicted and reversibility 16-82% after inhalation of salbutamol. Patients inhaled single doses of formoterol (Oxi...
journal_title：Respiratory medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1053/rmed.2002.1291
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND:Treatment with an inhaled corticosteroid (ICS) and long-acting bronchodilator is recommended for severe/very severe chronic obstructive pulmonary disease (COPD) patients with repeated exacerbations. This randomized, double-blind, double-dummy, parallel-group, 12-month multicenter study evaluated the effect o...
journal_title：Respiratory medicine
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.rmed.2011.07.020
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:We aimed to investigate the results of anti-tumor necrosis factor (TNF) therapy in patients with a previous history of tuberculosis (TB). METHODS:A total of 101 patients with a previous history of TB receiving TNF antagonists between December 2004 and September 2012 at the Asan Medical Center in South Korea...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2013.08.011
更新日期：2013-11-01 00:00:00
abstract：UNLABELLED:Misdiagnoses are inevitable when working hypotheses of asthma/COPD of General Practitioners (GPs) are not checked by spirometry. To reduce misdiagnoses, Asthma/COPD-support services (AC-services) offer support by performing spirometry assessed together with written medical history by consulting pulmonologist...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2012.03.002
更新日期：2012-08-01 00:00:00
abstract：:The purpose of this study was to explore respiratory health effects of indoor exposures to aldehydes and volatile organic compounds (VOCs) in elderly living in a population-based representative sample of French dwellings and to compare them to the rest of the occupants of the dwellings. Twenty VOCs were objectively me...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2013.07.015
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:Selection of heath-related quality of life (HRQL) instruments that are most responsive to changes in HRQL prevents investigators from drawing false-negative conclusions about the effectiveness of an intervention. The objective of this study was to compare the responsiveness of the Chronic Respiratory Questio...
journal_title：Respiratory medicine
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.rmed.2006.04.023
更新日期：2007-02-01 00:00:00
abstract：:Heart-lung transplantation involves denervation of the lungs below the tracheal anastomosis, with associated permanent loss of all pulmonary innervation except post-ganglionic efferent nerves. This is supported by loss of the cough reflex to inhaled USNDW, which also implies that the RARs which mediate this cough mech...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/s0954-6111(06)80248-9
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:Reduction in 30-day readmission rate after chronic obstructive pulmonary disease (COPD)-related hospitalization is a national objective. However, little is known about trends in readmission rates in recent years, particularly in priority populations defined by the Agency for Healthcare Research and Quality (...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2017.07.058
更新日期：2017-09-01 00:00:00
abstract：:The purpose of this randomized, double-blind parallel group study was to compare the safety, tolerability and acceptability of Easyhaler and Turbuhaler dry powder inhalers for the delivery of budesonide 800 microg day(-1) in adult asthmatic patients who had already been treated with inhaled corticosteroids for at leas...
journal_title：Respiratory medicine
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1053/rmed.2001.1261
更新日期：2002-04-01 00:00:00
abstract：BACKGROUND:Interstitial lung disease (ILD) is a common extramuscular manifestation of the idiopathic inflammatory myopathies (IIMs), dermatomyositis (DM) and polymyositis (PM). Patients with antisynthetase antibodies (ASA) demonstrate some or all of the features of the antisynthetase syndrome including IIM and ILD. It ...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2014.09.003
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:There are no validated patient diaries for evaluating respiratory symptoms in idiopathic pulmonary fibrosis (IPF). PURPOSE:To evaluate the performance properties of the chronic obstructive pulmonary disease (COPD) Evaluating Respiratory Symptoms™ (E-RS™: COPD) measure in patients with IPF. METHODS:Concept ...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2017.11.011
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Traditionally, outpatient visits for COPD are fixed, pre-planned by the pulmonologist. This is not a patient centered method, nor, in times of increasing COPD prevalence and resource constraints, perhaps the optimal method. OBJECTIVES:This pilot study, determined the effect of an on-demand-system, patient i...
journal_title：Respiratory medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.rmed.2014.05.011
更新日期：2014-08-01 00:00:00
abstract：PURPOSE:Although pulmonary rehabilitation (PR) improves function in people with chronic obstructive pulmonary disease (COPD), a community-based exercise program may be necessary to maintain functional capacity. We aimed to determine the effectiveness of a post-rehabilitation, community-based maintenance program on exer...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2020.106195
更新日期：2020-01-01 00:00:00
abstract：INTRODUCTION:The discrepancy rates of drug susceptibility testing (DST) results between solid and liquid media have been reported to range from 2.4 to 7.4% for isoniazid. Most isolate with isoniazid DST discrepancies between solid and liquid media test as susceptible on solid medium and resistant in liquid medium, howe...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2017.11.004
更新日期：2017-12-01 00:00:00
abstract：:To clarify the clinical features of pulmonary Mycobacterium avium-intracellulare complex (MAC) infection, we retrospectively evaluated clinical manifestations, laboratory data, chest and maxillary sinus computed tomographic scans and induced sputum findings in 26 with MAC infection in comparison with 104 patients with...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1053/rmed.2003.1496
更新日期：2003-06-01 00:00:00
abstract：INTRODUCTION AND AIM:Pseudomonas aeruginosa could acquire a mucoid phenotype due to mutations in mucA (mucoid Pseudomonas aeruginosa - mPA) that is a hallmark of poor prognosis in patients with bronchiectasis. Despite the higher prevalence of Pseudomonas aeruginosa in bronchiectasis, how mPA and non-mucoid Pseudomonas ...
journal_title：Respiratory medicine
pub_type： 杂志文章
doi：10.1016/j.rmed.2019.06.012
更新日期：2019-01-01 00:00:00
