Characteristics of pulmonary Mycobacterium avium-intracellulare complex (MAC) infection in comparison with those of tuberculosis.

Abstract:

:To clarify the clinical features of pulmonary Mycobacterium avium-intracellulare complex (MAC) infection, we retrospectively evaluated clinical manifestations, laboratory data, chest and maxillary sinus computed tomographic scans and induced sputum findings in 26 with MAC infection in comparison with 104 patients with tuberculosis (TB) infection. We found that carbohydrate antigen 19-9 (CA 19-9) and immunoglobulin A (IgA) in the serum and percentage of neutrophils in the sputum were significantly higher, and sinusitis was significantly more frequent in patients with MAC compared with patients with TB. MAC infection might be more strongly associated with impaired upper and lower airway defense mechanism in comparison with TB.

journal_name

Respir Med

journal_title

Respiratory medicine

authors

Watanabe K,Fujimura M,Kasahara K,Yasui M,Myou S,Watanabe A,Nakao S

doi

10.1053/rmed.2003.1496

subject

Has Abstract

pub_date

2003-06-01 00:00:00

pages

654-9

issue

6

eissn

0954-6111

issn

1532-3064

pii

S0954-6111(03)91496-X

journal_volume

97

pub_type

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