Surgical management of familial spontaneous pneumothorax.

abstract：:Collection of airway calibre and beta2-agonist data in large clinical trials and epidemiological surveys is sometimes difficult and may be an inefficient use of resources. The aim of this study was to determine whether the omission of the forced expiratory volume in 1 sec (FEV1) and beta2-agonist questions from the se...

journal_title：Respiratory medicine

authors： Juniper EF,O'Byrne PM,Roberts JN

更新日期：2001-05-01 00:00:00

abstract：INTRODUCTION:Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous respiratory disease with important extra-pulmonary features and comorbidities. The aim of this study was to assess clinical heterogeneity in a well-defined subgroup of individuals with COPD GOLD D, including possible gender differe...

journal_title：Respiratory medicine

authors： Sillen MJ,Franssen FM,Delbressine JM,Uszko-Lencer NH,Vanfleteren LE,Rutten EP,Wouters EF,Spruit MA

更新日期：2013-08-01 00:00:00

abstract：:The oxygen cost diagram (OCD) is a simple scale for quantifying a patient's evaluation of his tolerance to exercise frequently used in clinical trials; it has been shown to be well correlated with objective measures of capacity of ambulation such as the 6 min walk test (6' W). This study aimed to determine whether the...

journal_title：Respiratory medicine

authors： Janssens JP,Breitenstein E,Rochat T,Fitting JW

更新日期：1999-11-01 00:00:00

abstract：INRODUCTION:The mechanistic target of rapamycin inhibitors (mTORi) sirolimus and everolimus stabilize lung function in patients with pulmonary lymphangioleiomyomatosis (LAM) but do not induce remission. Pre-clinical studies suggest that simvastatin in combination with sirolimus induces LAM cell death. The objective of ...

journal_title：Respiratory medicine

authors： Krymskaya VP,Courtwright AM,Fleck V,Dorgan D,Kotloff R,McCormack FX,Kreider M

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Interleukin-32(IL-32)γ is a pro-inflammatory cytokine involved in the development and severity of chronic inflammatory diseases, but its role in asthma is unclear. OBJECTIVE:This study was conducted to evaluate the relationship of IL-32γ levels in sputum with the severity of asthma. METHODS:IL-32γ levels i...

journal_title：Respiratory medicine

authors： Kwon JW,Chang HS,Heo JS,Bae DJ,Lee JU,Jung CA,Son JH,Park JS,Kim SH,Min KU,Park CS

更新日期：2017-08-01 00:00:00

abstract：:Several clinical trials have shown that the inhaled beta2-agonists with long-acting properties, formoterol and salmeterol, may be effective in acute exacerbations of chronic obstructive pulmonary disease (COPD). However, there is a great deal of controversy regarding the timing and optimal dose of inhaled beta2-agonis...

journal_title：Respiratory medicine

authors： Cazzola M,Santus P,Matera MG,Carlucci P,Belloli E,Di Marco F,Centanni S

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:The 6-minute walk test distance (6MWD) has been shown to be a valid and responsive outcome measure in patients with idiopathic pulmonary fibrosis (IPF). The analyses were based, however, on a single phase 3 trial and require validation in an independent cohort. OBJECTIVE:To confirm the performance character...

journal_title：Respiratory medicine

authors： Nathan SD,du Bois RM,Albera C,Bradford WZ,Costabel U,Kartashov A,Noble PW,Sahn SA,Valeyre D,Weycker D,King TE Jr

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The 6-min walk test (6MWT) is a submaximal exercise test used to assess functional status in patients with cardiopulmonary diseases. Regression equations have previously been published as a normal reference for 6-min walk distance (6MWD) in healthy Caucasian adults. However, a recent study showed that the no...

journal_title：Respiratory medicine

authors： Alameri H,Al-Majed S,Al-Howaikan A

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:Although pulmonary rehabilitation (PR) improves function in people with chronic obstructive pulmonary disease (COPD), a community-based exercise program may be necessary to maintain functional capacity. We aimed to determine the effectiveness of a post-rehabilitation, community-based maintenance program on exer...

journal_title：Respiratory medicine

authors： Butler SJ,Desveaux L,Lee AL,Beauchamp MK,Brusco NK,Wang W,Goldstein RS,Brooks D

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:We explored the prevalence, clinical and physiologic correlates of pulmonary hypertension (PH), and screening strategies in patients with severe emphysema evaluated for the National Emphysema Treatment Trial (NETT). METHODS:Patients undergoing Doppler echocardiography (DE) and right heart catheterization we...

journal_title：Respiratory medicine

authors： Minai OA,Fessler H,Stoller JK,Criner GJ,Scharf SM,Meli Y,Nutter B,DeCamp MM,NETT Research Group.

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The optimal initial management of primary spontaneous pneumothorax (PSP) remains controversial. This study was to evaluate the safety and efficacy of intrapleural minocycline following aspiration for initial treatment of PSP. METHODS:Between January 2004 and November 2006, 64 patients with a first episode o...

journal_title：Respiratory medicine

authors： Chen JS,Tsai KT,Hsu HH,Yuan A,Chen WJ,Lee YC

更新日期：2008-07-01 00:00:00

abstract：:The efficacy of a non-steroidal anti-inflammatory agent (nedocromil sodium, NS) has been assessed in young children born prematurely who had recurrent respiratory symptoms at follow-up. In a randomized, double-blind cross-over trial, either two puffs of NS (2 mg puff-1) or placebo were administered three times a day v...

journal_title：Respiratory medicine

authors： Yüksel B,Greenough A

更新日期：1996-09-01 00:00:00

abstract：:The imbalance between oxidants and antioxidants is known to play an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Cigarette smoking is the most frequent factor responsible for development of COPD by leading to oxidant overload in the lower airways, due to presence of its own oxida...

journal_title：Respiratory medicine

authors： Nowak D,Kasielski M,Antczak A,Pietras T,Bialasiewicz P

更新日期：1999-06-01 00:00:00

abstract：:Citric acid has been used as a tussive agent in the investigation of the cough reflex. The mechanism of cough stimulation remains unclear. We conducted studies to compare the cough response of citric acid to an organic (acetic acid) and an inorganic acid (phosphoric acid). We also compared the cough response of citric...

journal_title：Respiratory medicine

authors： Wong CH,Matai R,Morice AH

更新日期：1999-01-01 00:00:00

abstract：:Airway dehydration and subsequent hyperosmolarity of periciliary fluid are considered critical events in exercise-induced bronchoconstriction (EIB). It has been shown that an in vitro hyperosmolar stimulation of basophils and mast cells with mannitol can induce the release of histamine and leukotrienes. The aim of thi...

journal_title：Respiratory medicine

authors： Moloney ED,Griffin S,Burke CM,Poulter LW,O'Sullivan S

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Alpha1-antitrypsin (AAT) deficiency, although largely under-diagnosed, is the underlying cause of approximately 1% of COPD cases. Lack of awareness leads to long delays in diagnostic testing. Subsequently, lifestyle and treatment choices with potentially positive effects on prognosis may be postponed. METHO...

journal_title：Respiratory medicine

authors： Greulich T,Ottaviani S,Bals R,Lepper PM,Vogelmeier C,Luisetti M,Ferrarotti I

更新日期：2013-09-01 00:00:00

abstract：:To answer the question as to whether pulmonary rehabilitation programs (PRP) induced increase in exercise tolerance (ET) is associated with increased levels of exhaled nitric oxide (eNO) in COPD patients of different degrees of severity, we designed a prospective and controlled study. Forty-seven stable COPD patients ...

journal_title：Respiratory medicine

authors： Clini E,Bianchi L,Foglio K,Vitacca M,Ambrosino N

更新日期：2002-05-01 00:00:00

abstract：:This double-blind, placebo-controlled, crossover study was performed to evaluate the effect of terbutaline administered by a turbuhaler on spirometry, walking distance and dyspnoea during exercise in patients with chronic obstructive lung disease (COLD) and to evaluate relationships between changes in spirometry and w...

journal_title：Respiratory medicine

authors： Evald T,Keittelmann S,Sindrup JH,Lange P

更新日期：1992-03-01 00:00:00

abstract：:Smoking and body mass index (BMI) are well-documented risk factors that contribute substantially to chronic obstructive pulmonary disease (COPD) and asthma. However, the relations among smoking, obesity, and COPD or asthma remain to be clarified. We conducted a population-based cross-sectional epidemiologic study to e...

journal_title：Respiratory medicine

authors： Cazzola M,Calzetta L,Lauro D,Bettoncelli G,Cricelli C,Di Daniele N,Rogliani P

更新日期：2013-09-01 00:00:00

abstract：:A double-blind, randomized crossover study in 28 asthmatic patients assessed the relative therapeutic index for inhaled formoterol and salbutamol. Pre-drug administration FEV1 (mean 2.08 l) was 49-93% of predicted and reversibility 16-82% after inhalation of salbutamol. Patients inhaled single doses of formoterol (Oxi...

journal_title：Respiratory medicine

authors： Rosenborg J,Larsson R,Rott Z,Böcskei C,Poczi M,Juhász G

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Diagnosing asthma cannot be always easy. It is important to consider the validity of the diagnostic tests, and/or how much more commonly they are positive in patients with asthma compared to healthy subjects and, particularly, to patients with asthma-like symptoms. OBJECTIVE:To evaluate the validity of diag...

journal_title：Respiratory medicine

authors： Di Lorenzo G,Mansueto P,Esposito-Pellitteri M,Ditta V,Castello F,Lo Bianco C,Leto-Barone MS,Di Fede G,Traverso M,Rotolo G,Vigneri S,Rini G

更新日期：2007-07-01 00:00:00

abstract：:The p53 gene is well known as a tumour suppressor gene. In addition, the mutated p53 gene is detected in a variety of human cancers including lung cancer, and is considered as an oncogene. Lung cancer is also frequently associated with interstitial lung diseases. Therefore, it may be possible to hypothesize that there...

journal_title：Respiratory medicine

authors： Hojo S,Fujita J,Yamadori I,Kamei T,Yoshinouchi T,Ohtsuki Y,Yamaji Y,Takahara J

更新日期：1998-02-01 00:00:00

abstract：:The HandiHaler is a novel breath-actuated dry powder system designed for the delivery of tiotropium 18microg daily in the treatment of COPD. We compared patient ability to use the HandiHaler or metered dose inhaler (MDI) device correctly 4 weeks after receiving brief instructions and device demonstration. A single-bli...

journal_title：Respiratory medicine

authors： Dahl R,Backer V,Ollgaard B,Gerken F,Kesten S

更新日期：2003-10-01 00:00:00

abstract：:The objective of this study was to evaluate the effect of lateral body position on gas exchange in patients with unilateral pleural effusion, with special reference to the influence of effusion volume. Thirty consecutive patients with unilateral pleural effusion, without evidence of parenchymal pulmonary involvement, ...

journal_title：Respiratory medicine

authors： Romero S,Martín C,Hernández L,Arriero JM,Benito N,Gil J

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVES:This randomized, double-blind, placebo-controlled, cross-over, Phase II dose-ranging study investigated the efficacy and safety of GP MDI (glycopyrronium administered by metered dose inhaler formulated using co-suspension delivery technology) compared with an open-label active comparator, salmeterol dry powd...

journal_title：Respiratory medicine

authors： Kerwin E,Wachtel A,Sher L,Nyberg J,Darken P,Siddiqui S,Duncan EA,Reisner C,Dorinsky P

更新日期：2018-06-01 00:00:00

abstract：:Nasal mucociliary system is the first line of defense of the upper airways and may be affected acutely by exposure to particulate matter (PM) from biomass burning. Several epidemiologic studies have demonstrated a consistent association between levels of air pollution from biomass burning with increases in hospitaliza...

journal_title：Respiratory medicine

authors： Ferreira-Ceccato AD,Ramos EM,de Carvalho LC Jr,Xavier RF,Teixeira MF,Raymundo-Pereira PA,Proença Cdos A,de Toledo AC,Ramos D

更新日期：2011-11-01 00:00:00

abstract：:Viral respiratory infections (VRI) can act as triggers for acute asthma exacerbations and contribute significantly to asthma-related healthcare costs. Knowing the patterns of viruses amongst asthmatics can be useful in treating and preventing these exacerbations and help decrease the burden they impose on patients and...

journal_title：Respiratory medicine

authors： Feddema JJ,Claassen E

更新日期：2020-11-01 00:00:00

abstract：:Measurement of exhaled nitric oxide is widely used in respiratory research and clinical practice, especially in patients with asthma. However, interpretation is often difficult, due to common interfering factors, and little is known about interactions between factors. We assessed the influences and interactions of fac...

journal_title：Respiratory medicine

authors： Dressel H,de la Motte D,Reichert J,Ochmann U,Petru R,Angerer P,Holz O,Nowak D,Jörres RA

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:We conducted a randomised controlled trial to assess the effects of daily breathing pattern changes to stable patients with COPD excluding the confounding factors of inspiratory muscle mobilization, by ensuring the load intensities of two inspiratory training devices were equal. PATIENTS AND METHODS:Sixty pati...

journal_title：Respiratory medicine

authors： Wu W,Guan L,Zhang X,Li X,Yang Y,Guo B,Ou Y,Lin L,Zhou L,Chen R

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:To compare the prognostic value of FENO with bronchoprovocation testing when the clinical course within the first year after assessment was taken into account; to compare the prognostic values with respect to eosinophilic versus non-eosinophilic inflammatory pattern. METHODS:Cross-sectional diagnostic study...

journal_title：Respiratory medicine

authors： Schneider A,Faderl B,Schwarzbach J,Welker L,Karsch-Völk M,Jörres RA

更新日期：2014-01-01 00:00:00