The 24 h duration of bronchodilator action of the salmeterol/fluticasone combination inhaler.

abstract：:We studied the validity of a recently introduced, handheld, electronic loading device in providing automatically processed information on external inspiratory work, power and breathing pattern during loaded breathing tasks in patients with COPD. Thirty-five patients with moderate to severe COPD performed an endurance ...

journal_title：Respiratory medicine

authors： Langer D,Jacome C,Charususin N,Scheers H,McConnell A,Decramer M,Gosselink R

更新日期：2013-04-01 00:00:00

abstract：UNLABELLED:Amiodarone-induced pulmonary toxicity (APT) is a serious adverse event that can lead to death. The aims of our study are to determine factors associated with mortality and to describe outcome and sequelae of patients with APT. METHODS:Forty-six patients with APT were divided into two groups according to sur...

journal_title：Respiratory medicine

authors： Mankikian J,Favelle O,Guillon A,Guilleminault L,Cormier B,Jonville-Béra AP,Perrotin D,Diot P,Marchand-Adam S

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:COPD is a prevalent disease that generates high use of resources. The objective of this study was to quantify the economic consequences of non-adherence to GOLD guidelines for the management of COPD patients. METHOD:An economic model was generated to compare different scenarios of observed vs. expected cost...

journal_title：Respiratory medicine

authors： Miravitlles M,Brosa M,Velasco M,Crespo C,Gobartt E,Diaz S,González-Rojas N

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:The 6-min walk test (6MWT) is a submaximal exercise test used to assess functional status in patients with cardiopulmonary diseases. Regression equations have previously been published as a normal reference for 6-min walk distance (6MWD) in healthy Caucasian adults. However, a recent study showed that the no...

journal_title：Respiratory medicine

authors： Alameri H,Al-Majed S,Al-Howaikan A

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Severe asthma is a heterogeneous disease. Patients with both eosinophilic and allergic asthma phenotypes may be eligible for treatment with mepolizumab and omalizumab. Evidence on the relative effectiveness of these treatments in this 'overlap' population would be informative for clinical and payer decision ...

journal_title：Respiratory medicine

authors： Cockle SM,Stynes G,Gunsoy NB,Parks D,Alfonso-Cristancho R,Wex J,Bradford ES,Albers FC,Willson J

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:To assess the exercise capacity, exercise habits, and lung function of preterm born children with bronchopulmonary dysplasia (BPD) compared to term born controls at school age. METHODS:Cardiopulmonary exercise test (CPET) by cycle ergometer and pulmonary function test were performed in children with BPD (n =...

journal_title：Respiratory medicine

authors： Prenzel F,Vogel M,Siekmeyer W,Körner A,Kiess W,Vom Hove M

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Sarcoidosis is characterised by a T-lymphocytic alveolitis with a typically increased T4/T8 ratio. The diagnostic value of this ratio is under debate. AIM OF THE WORK:We prospectively evaluated the influence of BAL pre-lavage and the impact of bronchial contamination on BAL differential cell count in 108 BA...

journal_title：Respiratory medicine

authors： Reichenberger F,Kleiber B,Baschiera B,Bubendorf L,Brutsche M,Dalquen P,Tamm M

更新日期：2007-09-01 00:00:00

abstract：STUDY OBJECTIVES:To test if morbid obesity causes pulmonary function changes and if massive weight loss have effect on pulmonary function (especially in subjects with BMI>or=60 kg/m(2)). PARTICIPANTS:Thirty-nine morbid obese subjects before and after massive weight loss. MEASUREMENTS AND RESULTS:Patients had baseline...

journal_title：Respiratory medicine

authors： Santana AN,Souza R,Martins AP,Macedo F,Rascovski A,Salge JM

更新日期：2006-06-01 00:00:00

abstract：:Gemcitabine is a newer pyrimidine analog used for the treatment of solid tumors. Though generally considered safe, it can cause pulmonary toxicity, which is generally mild and reversible. The purpose of this publication is to document a case of adult respiratory distress syndrome (ARDS) caused by Gemcitabine administr...

journal_title：Respiratory medicine

authors： Davidoff S,Shah RD,Arunabh T

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:A predominant feature of asthma is an accelerated rate of decline in forced expiratory volume in 1 s (FEV1), but data on the variability and factors associated with this change in patients with controlled asthma are largely unknown. METHODS:140 patients with controlled asthma were enrolled based on the Glob...

journal_title：Respiratory medicine

authors： Matsunaga K,Ichikawa T,Oka A,Morishita Y,Kanai K,Hiramatsu M,Akamatsu H,Kawabata H,Kikuchi T,Akamatsu K,Hirano T,Kou Y,Nakanishi M,Minakata Y,Yamamoto N

更新日期：2014-07-01 00:00:00

abstract：:Diffuse panbronchiolitis (DPB) is a distinctive form of small airway disease, which is characterized by chronic inflammation with lymphocyte infiltration around bronchioles. The aim of this study was to evaluate the importance of factors related to apoptosis in peribronchiolar lymphocytes of DPB. We employed immunohis...

journal_title：Respiratory medicine

authors： Kadota J,Mizunoe S,Mukae H,Mito K,Kishi K,Tokimatsu I,Nagai H,Tomono K,Kohno S,Nasu M

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Aspirin desensitization (AD) has been the only available modifying treatment in aspirin-exacerbated respiratory disease (AERD). The mechanisms of AD are nonetheless poorly understood. Though very effective, AD is limited by its risks and side-effects. OBJECTIVE:Moving forward to the targeted biologicals era...

journal_title：Respiratory medicine

authors： Bobolea I,Del Pozo V,Sanz V,Cabañas R,Fiandor A,Alfonso-Carrillo C,Salcedo MÁ,Heredia Revuelto R,Quirce S

更新日期：2018-10-01 00:00:00

abstract：UNLABELLED:Obesity is a major risk factor for poorly controlled asthma, but the reasons for poor asthma control in this patient population are unclear. Symptoms of depression have been associated with poor asthma control, and increase with higher body mass index (BMI). The purpose of this study was to assess whether de...

journal_title：Respiratory medicine

authors： Kapadia SG,Wei C,Bartlett SJ,Lang J,Wise RA,Dixon AE,American Lung Association Asthma Clinical Research Centers.

更新日期：2014-08-01 00:00:00

abstract：:Asthma progression is associated with airway remodeling and neo-vascularization. However, role of angiogenesis in these changes remains unclear and available data still incomplete. In this pilot study we verify usefulness of proteome profiler assay in screening of angiogenesis-related factors in exhaled breath condens...

journal_title：Respiratory medicine

authors： Grzela K,Litwiniuk M,Krejner A,Zagorska W,Grzela T

更新日期：2016-09-01 00:00:00

abstract：:The purpose of this study was to explore respiratory health effects of indoor exposures to aldehydes and volatile organic compounds (VOCs) in elderly living in a population-based representative sample of French dwellings and to compare them to the rest of the occupants of the dwellings. Twenty VOCs were objectively me...

journal_title：Respiratory medicine

authors： Bentayeb M,Billionnet C,Baiz N,Derbez M,Kirchner S,Annesi-Maesano I

更新日期：2013-10-01 00:00:00

abstract：:Current asthma management guidelines state that where a patient is receiving a low to moderate dose of inhaled corticosteroids and is still experiencing symptoms the dose of corticosteroid should be increased and, if necessary, a long-acting bronchodilator should be added. Many studies have now shown that the addition...

journal_title：Respiratory medicine

authors： Barnes PJ

更新日期：2001-08-01 00:00:00

abstract：:Exposure to mushroom spores may cause many respiratory allergic diseases, however, there has been no serial study in a mushroom factory to address this problem. The aim of this study was to investigate the serial changes in respiratory allergy and the incidence of hypersensitivity pneumonitis (HP) in mushroom workers....

journal_title：Respiratory medicine

authors： Tanaka H,Saikai T,Sugawara H,Tsunematsu K,Takeya I,Koba H,Matsuura A,Imai K,Abe S

更新日期：2001-12-01 00:00:00

abstract：:In this study we aimed to estimate direct medical costs of Chronic Obstructive Pulmonary Disease (COPD) by disease type; chronic bronchitis and emphysema. This study estimates direct costs in 1996 dollars using a prevalence approach and both aggregate and microcosting. A societal perspective is taken using prevalence,...

journal_title：Respiratory medicine

authors： Wilson L,Devine EB,So K

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Cystic fibrosis affects 1/3200 Caucasians. This genetic disease disturbs the ion and water homeostasis across epithelia, thus rendering mucus more viscous and harder to expel. Conventional treatments rely on the clapping method coupled with postural drainage. Despite the effectiveness of these procedures, th...

journal_title：Respiratory medicine

authors： Schieppati D,Germon R,Galli F,Rigamonti MG,Stucchi M,Boffito DC

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Positive end-expiratory pressure (PEEP) has been viewed as an essential component of mechanical ventilation in acute respiratory distress syndrome (ARDS) and acute lung injury (ALI). However, clinical trials have not yet convincingly demonstrated that high PEEP levels improve survival. The object of this stud...

journal_title：Respiratory medicine

authors： Oba Y,Thameem DM,Zaza T

更新日期：2009-08-01 00:00:00

abstract：:Systemic inflammation may be present in patients with chronic obstructive pulmonary disease (COPD). Exercise is known to elicit an inflammatory response. We hypothesized that the systemic inflammatory response to exercise might be exaggerated in COPD patients compared to healthy subjects. Sixteen COPD patients and 11 ...

journal_title：Respiratory medicine

authors： van Helvoort HA,van de Pol MH,Heijdra YF,Dekhuijzen PN

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND AND AIMS:The total serum IgE level is a marker of immunological activity in allergic bronchopulmonary aspergillosis (ABPA), and a 35% decline beyond six weeks is traditionally taken as criteria for remission. The aim of this study was to evaluate the magnitude and clinical significance of decline in serum Ig...

journal_title：Respiratory medicine

authors： Agarwal R,Gupta D,Aggarwal AN,Saxena AK,Saikia B,Chakrabarti A,Jindal SK

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Despite the manifestations of primary ciliary dyskinesia (PCD) in early life, the diagnosis is often much delayed. Since 1998 in Cyprus, we have established the only national diagnostic and clinical referral center for PCD. OBJECTIVE:To review the phenotypic features at presentation of PCD patients in Cypru...

journal_title：Respiratory medicine

authors： Yiallouros PK,Kouis P,Middleton N,Nearchou M,Adamidi T,Georgiou A,Eleftheriou A,Ioannou P,Hadjisavvas A,Kyriacou K

更新日期：2015-03-01 00:00:00

abstract：:Haemodynamic studies at rest and during exercise together with radionuclide ventriculography, pulmonary function and clinical well-being assessment were evaluated in ten patients with COPD and secondary pulmonary hypertension (mean PAP 25 mm Hg), before and after 6 months therapy with pirbuterol 20 mg thrice daily. De...

journal_title：Respiratory medicine

authors： Neilly JB,Carter R,Tweddel A,Martin W,Hutton I,Banham SW,Stevenson RD

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Impaired cardiac function and sleep-disordered breathing (SDB) are associated with progression of chronic kidney disease (CKD) in heart failure (HF) patients. Adaptive servo-ventilation (ASV) therapy improves cardiac function in HF patients regardless of the SDB severity through hemodynamic support and preve...

journal_title：Respiratory medicine

authors： Koyama T,Watanabe H,Terada S,Makabe S,Igarashi G,Nobori K,Ito H

更新日期：2011-12-01 00:00:00

abstract：:The diagnostic value of isocapnic hyperventilation of cold air (IHCA) is not fully established. All 342 adult patients in whom IHCA had been performed because of a clinical suspicion of asthma between 1992 and 1994 were analysed retrospectively in the authors' hospital. In addition, 26 healthy subjects were recruited....

journal_title：Respiratory medicine

authors： Koskela HO,Räsänen SH,Tukiainen HO

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Data on the risk of death following an asthma exacerbation are scarce. With this multinational cohort study, we assessed all-cause mortality rates, mortality rates following an exacerbation, and patient characteristics associated with all-cause mortality in asthma. METHODS:Asthma patients aged ≥18 years and...

journal_title：Respiratory medicine

authors： Engelkes M,de Ridder MA,Svensson E,Berencsi K,Prieto-Alhambra D,Lapi F,Giaquinto C,Picelli G,Boudiaf N,Albers FC,Cockle SM,Bradford ES,Suruki RY,Brusselle GG,Rijnbeek PR,Sturkenboom MC,Verhamme KM

更新日期：2020-01-01 00:00:00

abstract：:To document the rate and cost of antibiotic prescribing for patients diagnosed only with influenza during US ambulatory care visits. Federal survey data for 1997-2001 were used to estimate outpatient trends for all patients and healthy people age 5-49 years. Cost estimates were based on Medicare payments and Red Book ...

journal_title：Respiratory medicine

authors： Ciesla G,Leader S,Stoddard J

更新日期：2004-11-01 00:00:00

abstract：:The increasing prevalence of allergic sensitization to indoor allergens such as dust mites, pets and cockroaches is the result of the changes in indoor environments induced by human activities. The Westernized lifestyle and the increasing time spent indoors determine a reduction in natural air ventilation and, consequ...

journal_title：Respiratory medicine

authors： Liccardi G,Cazzola M,D'Amato M,D'Amato G

更新日期：2000-11-01 00:00:00

abstract：:There is a subclinical activation of coagulation and fibrinolysis system in lung cancer. Alterations in hemostatic system are seen frequently in lung cancer correlated with the prognosis of disease. In this prospective study, our purpose was to investigate the prognostic significance of hemostatic markers in patients ...

journal_title：Respiratory medicine

authors： Unsal E,Atalay F,Atikcan S,Yilmaz A

更新日期：2004-02-01 00:00:00