Gemcitabine-induced respiratory failure associated with elevated erythrocyte sedimentation rate (ESR).

Abstract:

:Gemcitabine is a newer pyrimidine analog used for the treatment of solid tumors. Though generally considered safe, it can cause pulmonary toxicity, which is generally mild and reversible. The purpose of this publication is to document a case of adult respiratory distress syndrome (ARDS) caused by Gemcitabine administration. The patient was noticed to have the extreme elevation of erythrocyte sedimentation rate (ESR) (> 100 mm/h) at the time of diagnosis. We observed excellent response to the corticosteroids. The ESR trended back to normal after the resolution of her symptoms thereby suggesting the utility of monitoring ESR in the diagnosis and management of Gemcitabine-induced pulmonary toxicity.

journal_name

Respir Med

journal_title

Respiratory medicine

authors

Davidoff S,Shah RD,Arunabh T

doi

10.1016/j.rmed.2005.08.002

subject

Has Abstract

pub_date

2006-04-01 00:00:00

pages

760-3

issue

4

eissn

0954-6111

issn

1532-3064

pii

S0954-6111(05)00325-2

journal_volume

100

pub_type

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