Abstract：
:Toxoplasma gondii is an opportunistic protozoan parasite that differentiates into latent cysts (bradyzoite) that can be reactivated during immunosuppression. TgSRCAP (Toxoplasma gondii Snf2-related CBP activator protein) is a SWI2/SNF2 family chromatin remodeler whose expression increases during cyst development. Identifying the proteins associating with TgSRCAP during the pre-cyst stage (tachyzoite) will increase our understanding of how parasite differentiation is initiated. We employed the yeast two-hybrid system to identify proteins that may interact directly with TgSRCAP. A stretch of 1,060 amino acids between ATPase subdomains IV and V of TgSRCAP was chosen as "bait" since the corresponding region in human SRCAP interacts with other proteins, including CREB binding protein. We have identified several novel parasite-specific transcription factors predicted to be in the T. gondii genome. Metabolic enzymes that may participate in cyst development were also identified as interacting with TgSRCAP.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Nallani KC,Sullivan WJ Jrdoi
10.1007/s00436-004-1291-5subject
Has Abstractpub_date
2005-03-01 00:00:00pages
236-42issue
4eissn
0932-0113issn
1432-1955journal_volume
95pub_type
杂志文章abstract：:One of the main drawbacks of experimental amebiasis is the lack of an adequate animal model for invasive intestinal lesions. Mongolian gerbils are useful because both intestinal and hepatic amebiasis can be produced experimentally with Entamoeba histolytica trophozoites. In this paper we show results obtained with in ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050228
更新日期：1997-01-01 00:00:00
abstract：:Neurocysticercosis (NC) is one of the most important diseases caused by parasites affecting the central nervous system. We fractionated by ion-exchange chromatography using diethylaminoethyl (DEAE)-sepharose resin the total saline extract (S) from Taenia solium metacestodes and evaluated obtained fractions (DEAE S1 an...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-3908-7
更新日期：2014-07-01 00:00:00
abstract：:The accuracies of relative gene expressions as determined by quantitative real-time polymerase chain reaction are largely dependent on the variabilities of the reference genes used. Validation of the stabilities of reference genes under experimental conditions is an essential initial step for comparative studies on th...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1195-x
更新日期：2009-01-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-012-3034-3
更新日期：2012-11-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06799-w
更新日期：2020-12-01 00:00:00
abstract：:Parasites of managed bees can disrupt the colony success of the host, but also influence local bee-parasite dynamics, which is regarded as a threat for wild bees. Therapeutic measures have been suggested to improve the health of managed bees, for instance, exploiting the bees' RNA interference (RNAi) pathway to treat ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-6176-0
更新日期：2019-02-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4669-7
更新日期：2015-11-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-2187-1
更新日期：2011-03-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-0888-5
更新日期：2008-05-01 00:00:00
abstract：:A taste-enhancement process for cold-stored, raw shell-stock Crassostrea virginica oysters (i.e., application of table salt to shells) when externally contaminated with human enteropathogens intensified spillage of these enteropathogens to oyster' storage containers (77% compared to 27% for controls) but did not, howe...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0664-y
更新日期：2007-11-01 00:00:00
abstract：:Entamoeba histolytica forms chitin-walled cysts during encystation process, where formation of the cyst wall needs not only chitin synthase but also chitinase. During excystation, quadruplet amoebae emerge from the chitin-walled cysts by dissolving the wall, so that chitinase may be necessary for excystation process a...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2270-2
更新日期：2011-08-01 00:00:00
abstract：:Sarcocystis sarcocysts are common in muscles of herbivores but are rare in muscles of carnivores. Here, we report sarcocysts in the muscles of a gray wolf (Canis lupus) from Alaska, USA, for the first time. Sarcocysts extracted from the tongue of the wolf were up to 900 μm long and slender and appeared to have a relat...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-016-5067-5
更新日期：2016-07-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章,评审
doi：10.1007/s00436-015-4898-9
更新日期：2016-04-01 00:00:00
abstract：:In several studies, different antigenic preparations and diverse immunological tests were applied for serodiagnosis of Fasciola hepatica infections. Most of these preparations showed cross-reactivity with proteins of other parasites. Application of purified antigens might reduce these cross-reactivities. Here, we used...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-016-5049-7
更新日期：2016-08-01 00:00:00
abstract：:A novel approach to control strategies for integrated blood-feeding parasite management is in high demand, including the use of biological control agents. The present study aims to determine the efficacy of optimized crude extract of actinomycetes strain LK1 as biological control agent against the fourth-instar larvae...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-013-3585-y
更新日期：2013-11-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00928421
更新日期：1991-01-01 00:00:00
abstract：:The performance of a rapid immunochromatographic test for the detection of Dirofilaria immitis antigens (Speed Diro™; BVT-Virbac, France) was assessed in 49 experimentally infected dogs and in 244 naturally infected animals; 142 dogs and 102 cats. In experimentally infected dogs, Speed Diro™ showed a sensitivity of 90...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-017-5709-2
更新日期：2018-01-01 00:00:00
abstract：:Understanding the fundamental factors influencing the epidemiology of wildlife disease is essential to determining the impact of disease on individual health and population dynamics. The host-pathogen-environment relationship of the endangered Australian sea lion (Neophoca cinerea) and the parasitic hookworm, Uncinari...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-3997-3
更新日期：2014-09-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360000248
更新日期：2000-10-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-005-1346-2
更新日期：2005-06-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00531638
更新日期：1988-01-01 00:00:00
abstract：:Recent studies have shown that hormones could induce anti-parasitic functions of the host immune system; thus, the aim of the present study was to estimate the seroprevalence of Toxoplasma gondii antibodies by an enzyme-linked immunosorbent assay in a Polish population of women and men with hyperprolactinaemia (n = 23...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0824-0
更新日期：2008-03-01 00:00:00
abstract：:The purpose of this study was to genetically characterize and phylogenetically analyze the Cryptosporidium spp. isolated from exotic birds commercialized in popular markets, commercial aviaries, and pet shops located in Rio de Janeiro, Brazil. Fecal samples from individually housed birds were collected and subjected t...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2636-5
更新日期：2012-04-01 00:00:00
abstract：:The Chrysomya megacephala (Fabricius, 1794) (Diptera: Calliphoridae) has a worldwide distribution and is considered of medical and veterinary importance. Its synanthropic behavior combined with the visitation of decaying organic matter allows it to mechanically transmit pathogens to human and animals. Pyrethroids are ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06933-8
更新日期：2020-10-17 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360000357
更新日期：2001-07-01 00:00:00
abstract：:Clinostomum complanatum is an important trematode in fishes, birds of the family Ardeidae, and humans. Until now, limited knowledge is available regarding its molecular epidemiology, ecology, and phylogenetic study. Knowledge of the full mitochondrial genome of C. complanatum will provide important information for the...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-016-5102-6
更新日期：2016-08-01 00:00:00
abstract：:Antibody responses to naturally acquired Plasmodium relictum and P. elongatum infections, blood parasitemia, and disease signs were investigated in 23 naive juvenile African black-footed penguins (Spheniscus demersus). Anti-Plasmodium spp. immunoglobulins were detected by enzyme-linked immunosorbent assay (ELISA) usin...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00932944
更新日期：1994-01-01 00:00:00
abstract：:SAG2 locus, the coding gene of the P22 protein, has been widely used for the molecular epidemiology of Toxoplasma gondii and characterization of the parasite isolates with two separate polymerase chain reaction (PCR)-restriction fragment length polymorphism (RFLP) processes. To re-assess the resolution power and suita...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-006-0449-8
更新日期：2007-06-01 00:00:00
abstract：:Nosema ceranae is a ubiquitous microsporidian pathogen infecting the midgut of honey bees. The infection causes bee nosemosis, a disease associated with malnutrition, dysentery, and lethargic behavior, and results in considerable economic losses in apiculture. The use of a rapid, sensitive, and inexpensive DNA-based m...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06915-w
更新日期：2020-12-01 00:00:00
abstract：:Sheep infected with the triclabendazole-susceptible Cullompton isolate of Fasciola hepatica were dosed with 15 mg/kg of compound alpha at 12 weeks post-infection. Adult flukes were recovered from the bile ducts at 24, 48, and 72 h post-treatment (p.t.). Changes to the spermatogenic cells in the testis were examined by...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-009-1649-9
更新日期：2010-01-01 00:00:00
