Abstract:
:Excretory/secretory (ES) products collected from exsheathed L3 or parasitic stages of Haemonchus contortus were tested in vitro for gastrin stimulatory properties using an ovine abomasal antral mucosal preparation. In addition, the motility of exsheathed L3 and parasites recovered on weeks 2, 6 and 8 post-infection was studied in water, saline, saline with glucose or ovine blood and in HBSS pH 2.5-7.4. Parasitic stages became immotile rapidly in water and HBSS pH 2.5, more slowly in HBSS pH 3.5, but nearly 100% remained motile for 48 h when blood was included in the medium. Exsheathed L3 motility was reduced only by water and HBSS pH 2.5, and then only in the second week of incubation. Gastrin secretion was not consistently increased by any of the parasite ES products tested in vitro, therefore, they probably do not stimulate the G cell directly to produce the hypergastrinaemia seen in parasitised sheep.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Haag E,Lawton D,Simpson HVdoi
10.1007/s00436-004-1274-6subject
Has Abstractpub_date
2005-01-01 00:00:00pages
155-60issue
2eissn
0932-0113issn
1432-1955journal_volume
95pub_type
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