Abstract:
BACKGROUND:The Senning operation for transposition of the great arteries (TGA) was first introduced by Senning in 1959 and was revived by Quaegebeur et al. in the late 1970s, thus becoming the intervention of choice for the correction of TGA in many centers. HYPOTHESIS:The purpose of this study was to evaluate the long-term follow-up of a group of patients undergoing surgery with the Senning procedure for TGA. METHODS:From November 1978 to November 1987, 73 consecutive patients underwent the Senning operation. The 70 survivors had an average follow-up of 19 years (16-25 years). RESULTS:(1) Cardiac rhythm: with time there was a progressive decrease in stable sinus rhythm (60% after 20 years) and a progressive increase of supraventricular tachyarrhythmias requiring therapy (10% after 20 years). (2) Right ventricular function: 20% of the patients had reduced ejection fraction. (3) Late mortality: in the last 12 years of follow-up years there were two sudden deaths (2.8%). (4) Functional status: 80% of patients were in NYHA class I, 17% in class II, and 3% in class III. CONCLUSIONS:Our results confirm that the patients who undergo the Senning procedure have a progressive loss of sinus rhythm, an increase in active arrhythmias, and other important adverse outcomes such as late sudden death and a decrease in right ventricular function; however, most patients (93% in our series) are alive and in good functional status.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
Agnetti A,Carano N,Cavalli C,Tchana B,Bini M,Squarcia U,Frigiola Adoi
10.1002/clc.4960271107subject
Has Abstractpub_date
2004-11-01 00:00:00pages
611-4issue
11eissn
0160-9289issn
1932-8737journal_volume
27pub_type
杂志文章abstract::The long-term survival rate following acute myocardial infarction (AMI) was studied in 358 patients in central Japan who were monitored for 8 to 20 years after discharge from hospital for AMI. Fifteen-year cardiac survival rates were 65% in males and 72% in females. In both sexes, the survival rate decreased with incr...
journal_title:Clinical cardiology
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pub_type: 杂志文章,评审
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journal_title:Clinical cardiology
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pub_type: 杂志文章,多中心研究,随机对照试验
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