Abstract:
BACKGROUND:Limited information exists regarding the association between subjective well-being (SWB) and systolic blood pressure (SBP) among hypertensive patients with coronary artery disease (CAD). HYPOTHESIS:We tested the hypothesis that there is an association between SBP and SWB. METHODS:We studied 22,576 hypertensive CAD patients > or = 50 years old in the INternational VErapamil SR-Trandolapril Study (INVEST), a randomized, blinded-endpoint trial of antihypertensive therapy in stable CAD patients. At each study visit, patients rated their SWB in the previous 4 weeks as "excellent," "good," "fair," or "poor" prior to SBP recordings. The outcome measure was SWB of "fair" or "poor." A longitudinal analysis using generalized estimating equations was performed to assess the association between SBP and odds of reporting fair/poor SWB, controlling for baseline SWB of fair/poor and angina reported during the study. RESULTS:Patients with higher SBP had higher odds of reporting fair/poor SWB. Specifically, compared with patients with SBP of < or = 120, patients with SBP 140-150 > 150 - < or = 160 and > 160 had about 90% and 2.5 times greater odds of feeling fair/poor, respectively (adjusted odds ratio [OR]: 1.5990, 95% confidence interval [CI]: 1.81-2.00 and adjusted OR: 2.53, 95% CI: 2.41-2.66). Those who reported angina in the 4 wks prior to a protocol visit had 2.2 times greater odds of reporting fair/poor SWB (adjusted OR: 2.2, 95% CI: 2.13-2.27). Female gender, black race, history of smoking, diabetes, myocardial infarction, stroke, and cancer also increased the odds of reporting fair/poor SWB. CONCLUSIONS:Among hypertensive CAD patients, higher on-treatment SBP is associated with greater odds of fair/poor SWB during follow-up.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
Gong Y,Handberg EM,Gerhard T,Cooper-Dehoff RM,Ried LD,Johnson JA,Pepine CJ,INVEST Investigators.doi
10.1002/clc.20501subject
Has Abstractpub_date
2009-11-01 00:00:00pages
627-32issue
11eissn
0160-9289issn
1932-8737journal_volume
32pub_type
杂志文章,多中心研究,随机对照试验abstract:BACKGROUND:Electromechanical (EM) coupling heterogeneity is significant in long QT syndrome (LQTS), particularly in symptomatic patients; EM window (EMW) has been proposed as an indicator of interaction and a better predictor of arrhythmia than QTc. HYPOTHESIS:To investigate the dynamic response of EMW to exercise in ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23132
更新日期:2019-02-01 00:00:00
abstract::This study affirms that compliance with medical regimen in a university cardiac clinic favorably influences patient outcome. The multiplicity of factors influencing compliance are emphasized, as is the need for continuing physician evaluation of compliance, and attempts to favorably influence it. ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960030311
更新日期:1980-06-01 00:00:00
abstract:BACKGROUND:The Senning operation for transposition of the great arteries (TGA) was first introduced by Senning in 1959 and was revived by Quaegebeur et al. in the late 1970s, thus becoming the intervention of choice for the correction of TGA in many centers. HYPOTHESIS:The purpose of this study was to evaluate the lon...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960271107
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Acute coronary syndromes (ACS) are characterized by activation of systemic and local inflammatory mediators. The interrelation between these soluble inflammatory markers and their association with markers of myocardial necrosis have not been extensively studied. HYPOTHESIS:The study was undertaken to evalua...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960280405
更新日期:2005-04-01 00:00:00
abstract::A total of 1150 consecutive patients (1052 males and 98 females; age 51.2 +/- 10.1 years) with suspected coronary artery disease (Group I) were subjected to fluoroscopy for detection of coronary artery calcification (CAC) and coronary angiography. Another group (Group II) of 120 patients (95 males and 25 females; age ...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960110705
更新日期:1988-07-01 00:00:00
abstract::Cardiogenic shock usually is the result of marked depression in myocardial function. Rapid recognition and stabilization are essential if the patient is to survive. A variety of cardiovascular conditions can lead to cardiogenic shock; the most common of these is acute myocardial infarction. Once stabilization of the c...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960160305
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND:Left ventricular hypertrophy (LVH) on the electrocardiogram (ECG) may be masked in the presence of complete right bundle-branch block (RBBB). Left bundle-branch block on the ECG is associated with LVH at autopsy in 93% of hearts studied. However, RBBB does not predict LVH and the usual ECG criteria applied f...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960210209
更新日期:1998-02-01 00:00:00
abstract:BACKGROUND:Recently, electrocardiogram (ECG) criteria have been proposed for the diagnosis of acute myocardial infarction (AMI) in the presence of left bundle-branch block (LBBB). However, clinical experience indicates that such ECG changes indicative of AMI are occasionally noted in clinically stable patients with LBB...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960241004
更新日期:2001-10-01 00:00:00
abstract::Left ventricular systolic dysfunction (LVSD) and clinical heart failure are common complications of acute myocardial infarction (AMI) and result in substantially increased mortality and morbidity. Evidence-based cardiovascular protective therapies, including angiotensin-converting enzyme inhibitors, beta blockers, ant...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960290103
更新日期:2006-01-01 00:00:00
abstract::The treatment of hypertension continues to be challenging due to the lack of understanding regarding underlying modulators of blood pressure as well as co-existing conditions such as atherosclerosis and diabetes. This has led to uncertainty regarding treatment strategy and intensity. The INternational VErapamil SR/tra...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960241705
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:The incidence of congestive heart failure (CHF) has not significantly declined over the past 50 years, and overall survival rates are low at 5 years following diagnosis. Numerous studies have shown low serum sodium to be a poor prognostic indicator of all cause mortality in CHF patients. HYPOTHESIS:The goal...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20560
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Although ischemic threshold reportedly is lower in the early morning than in the afternoon, the mechanisms that account for the diurnal change in minimal coronary vascular resistance in the potentially ischemic area are unknown. HYPOTHESIS:We hypothesized that calcium-channel blockers and alpha 1 blockers m...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960210512
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:Electronic health record systems (EHR) are expected to facilitate higher quality patient care; however, studies evaluating EHR effectiveness in improving care have yielded mixed results. HYPOTHESIS:Implementation of a performance improvement system in outpatient practices with EHR may better demonstrate the...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.21971
更新日期:2012-03-01 00:00:00
abstract::A 62-year-old man was admitted to our hospital with unstable angina. The coronary arteriography showed the occlusion of the left anterior descending artery and other stenotic lesions. The patient underwent an aortocoronary bypass operation, but unfortunately he did not survive. Surprisingly, the necropsy revealed him ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960091113
更新日期:1986-11-01 00:00:00
abstract::This manuscript was written in an effort to emphasize the points made by Porter et al. (Clin Cardiol 1997; 20:971-973). Right ventricular infarction may be erroneously interpreted as an anteroseptal infarction because of elevation of the S-T segments in leads V1-V4. The two can be separated when, using the Grant metho...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960210411
更新日期:1998-04-01 00:00:00
abstract::Patients with coronary artery disease have a variety of treatment options available to them. These include medications to control anginal episodes and, when appropriate, revascularization interventions in the form of coronary artery bypass graft and angioplasty. Despite advances in the treatment of angina, a substanti...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960251407
更新日期:2002-12-01 00:00:00
abstract::Arrhythmogenic right ventricular dysplasia (ARVD) is a rare cardiomyopathy characterized by the progressive replacement of cardiomyocytes by fatty and fibrous tissue in the right ventricle (RV). These infiltrations lead to cardiac electrical instability and ventricular arrhythmia. Current treatment for ARVD is empiric...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/clc.22884
更新日期:2018-03-01 00:00:00
abstract::A case of systemic hypotension with volume depletion not responding to intravenous fluids was found to have features of cardiac tamponade on two-dimensional (2-D) echocardiography. Intracardiac pressures were normal on cardiac catheterization. An interesting observation was the presence of left ventricular (LV) collap...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960210318
更新日期:1998-03-01 00:00:00
abstract::Natural history studies in heart failure have shown that increases in left ventricular (LV) volume and LV mass are directly related to future deterioration in LV performance and a less favorable clinical course. Despite the recognized importance of remodeling in heart failure, very little is known about the basic mech...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960211304
更新日期:1998-12-01 00:00:00
abstract::This work attempted to study the segmental wall motion on left ventriculograms, in terms of segmental shortening, velocity of segmental shortening, and temporal sequences of various events in systole as well as in diastole. The ability of such a method to characterize patterns of normal regional wall motion and to det...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960090201
更新日期:1986-02-01 00:00:00
abstract::Most series of patients with ventricular tachycardia (VT) of right bundle-branch block (RBBB)-left axis deviation (LAD) morphology include young individuals with no overt evidence of structural heart disease. In the present report, the clinical and electrophysiologic findings in two patients with verapamil-responsive ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960150617
更新日期:1992-06-01 00:00:00
abstract::A 55-year-old Caucasian woman suddenly developed substernal chest pain at rest accompanied by pallor, diaphoresis, nausea, and vomiting. Physical examination was otherwise unremarkable. The resting ECG showed T-wave inversion in all anterior leads which returned to normal 24 h after the onset of the symptoms. The pain...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960100614
更新日期:1987-06-01 00:00:00
abstract::Warfarin and other 4-hydroxycoumarins are effective antithrombotic agents. They affect four blood coagulation proteins that act sequentially to produce thrombin. Coumarin therapy decreases the biological activity of these proteins, and therefore decreases the rate at which blood clots. As the mechanism by which these ...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:
更新日期:1990-04-01 00:00:00
abstract::Computer interpretation of electrocardiograms is far from adequate. This paper highlights a particular type of computer error that is merely symbolic of the large number of errors the computer can make. In addition to computer errors in electrocardiography, it is likely that computer interpretation has diminished the ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960190711
更新日期:1996-07-01 00:00:00
abstract::Hospitals typically use Center for Medicare and Medicaid Services' (CMS) Hospital Readmission Reduction Program (HRRP) administrative reports as the standard of heart failure (HF) admission quantification. We aimed to evaluate the HF admission population identified by CMS HRRP definition of HF hospital admissions comp...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22711
更新日期:2017-09-01 00:00:00
abstract::In-coordinate mitral annulus movement might participate in the pathogenesis of functional mitral regurgitation. We evaluated a relationship between indices of mitral annulus systolic asynchrony and mitral regurgitation in patients after myocardial infarction in order to determine independent determinants of effective ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20131
更新日期:2007-10-01 00:00:00
abstract::We describe two patients in whom spontaneous angina following acute myocardial infarction (postinfarction angina caused by coronary artery spasm) and worsening angina were successfully eliminated after clinical dosage of oral diltiazem, while marked sinus node suppression developed and temporary pacing was performed. ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960071110
更新日期:1984-11-01 00:00:00
abstract:BACKGROUND:Statins are the most widely used lipid lowering therapies which reduce cardiovascular risk, but are associated with muscular adverse events (AEs). Idiopathic inflammatory myopathies (IIM) are autoimmune diseases of the muscle with higher risk of cardiovascular disease. More data is needed regarding statin sa...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23375
更新日期:2020-07-01 00:00:00
abstract::A patient with vasospastic angina who developed myocardial ischemia following ethanol ingestion but not after exercise was described. Myocardial ischemia was evidenced by electrocardiograms (ECGs) and thallium-201 scintigrams. The blood acetaldehyde level after ethanol ingestion was abnormally high. The time course an...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960160514
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND AND HYPOTHESIS:Previous research has failed to document temporal changes in epinephrine levels in patients with neurally mediated syncope associated with exercise. The purpose of this study was to investigate the role of circulatory catecholamines in exercise-induced neurally mediated syncope, specifically f...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00