Asynchronous movement of mitral annulus: an additional mechanism of ischaemic mitral regurgitation.

Abstract:

:In-coordinate mitral annulus movement might participate in the pathogenesis of functional mitral regurgitation. We evaluated a relationship between indices of mitral annulus systolic asynchrony and mitral regurgitation in patients after myocardial infarction in order to determine independent determinants of effective regurgitant orifice (ERO) area in a multivariate regression model. Tissue Doppler echocardiographic studies and quantitative analysis of mitral regurgitation were performed in 40 patients (33 men, 7 women, mean age 60.1 +/- 9.2 years) with a history of Q-wave myocardial infarction, with and without significant functional mitral regurgitation.A multivariate regression model showed that mitral annulus movement asynchrony index-difference between the longest and the shortest time from the R wave in the electrocardiogram to the cessation of systolic movement of the four aspects of mitral annulus, is an independent from ejection fraction, sphericity index, tenting, annulus diameter and infarct location, determinant of mitral regurgitation ERO area (r(2) change 0.72, p

journal_name

Clin Cardiol

journal_title

Clinical cardiology

authors

Szymanski P,Klisiewicz A,Hoffman P

doi

10.1002/clc.20131

subject

Has Abstract

pub_date

2007-10-01 00:00:00

pages

512-6

issue

10

eissn

0160-9289

issn

1932-8737

journal_volume

30

pub_type

杂志文章
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