Clinical trial experience around the globe: focus on calcium-channel blockers.

abstract：BACKGROUND:The Senning operation for transposition of the great arteries (TGA) was first introduced by Senning in 1959 and was revived by Quaegebeur et al. in the late 1970s, thus becoming the intervention of choice for the correction of TGA in many centers. HYPOTHESIS:The purpose of this study was to evaluate the lon...

journal_title：Clinical cardiology

authors： Agnetti A,Carano N,Cavalli C,Tchana B,Bini M,Squarcia U,Frigiola A

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Plaque rupture with subsequent transient thrombotic coronary occlusion by a fast-dissolving clot is one of the proposed pathogenic mechanisms in Takotsubo cardiomyopathy (TC). HYPOTHESIS:The aim of this study was to seek evidence for the hypothesis of transient coronary thrombosis as the underlying mechanis...

journal_title：Clinical cardiology

authors： Haghi D,Roehm S,Hamm K,Harder N,Suselbeck T,Borggrefe M,Papavassiliu T

更新日期：2010-05-01 00:00:00

abstract：:Far less attention has been paid to the prognostic effect of right-side heart disease on outcomes after transcatheter aortic valve replacement (TAVR) when compared with the left side. Therefore, we performed a systematic review and meta-analysis on the impact of tricuspid regurgitation (TR) and right ventricular (RV) ...

journal_title：Clinical cardiology

authors： Fan J,Liu X,Yu L,Sun Y,Jaiswal S,Zhu Q,Chen H,He Y,Wang L,Ren K,Wang J

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:It is unclear whether more severe coronary atherosclerosis is a prerequisite to an initial acute coronary event in women vs men. HYPOTHESIS:Women may have more severe coronary atherosclerosis than men in patients with acute coronary event. METHODS:We used intravascular optical coherence tomography (OCT) to...

journal_title：Clinical cardiology

authors： Sun R,Sun L,Fu Y,Liu H,Xu M,Ren X,Yu H,Dong H,Liu Y,Zhu Y,Tian J,Yu B

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Although nocturnal pulseoximetry is routinely performed in obstructive sleep apnea syndrome (OSAS), pulseoximetry over a 24-h period has not been studied. HYPOTHESIS:The purpose of the study was to determine whether simultaneous 24-h oxygen desaturation and electrocardiographic (ECG) recording might be used...

journal_title：Clinical cardiology

authors： Noda A,Ito R,Okada T,Yasuma F,Nakashima N,Yokota M

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:In clinical cardiology, heart rate variability is a putative index of autonomic cardiovascular function. Signs of reduced vagal activity are not only associated with an enhanced risk of sudden cardiac death, but such impaired heart rate variability became a new predictor of sudden cardiac death and other mor...

journal_title：Clinical cardiology

authors： Otsuka K,Cornélissen G,Halberg F

更新日期：1997-07-01 00:00:00

abstract：:Dobutamine stress echocardiography (DSE) is a reliable cardiac risk stratifier that has widespread applicability because of its clinical accuracy and cost effectiveness. Dobutamine has positive inotropic and chronotropic effects and is commonly used in patients who cannot exercise or achieve an adequate heart rate res...

journal_title：Clinical cardiology

authors： Usher BW Jr,O'Brien TX

更新日期：2000-08-01 00:00:00

abstract：:At present, there is an exponential use of new interventional techniques whose proper role and value have not yet been defined. The intracoronary stent is just one example. There is no doubt that stents can be implanted with a high technical success rate associated with highly predictable immediate angiographic result...

journal_title：Clinical cardiology

authors： de Jaegere PP,de Feyter PJ,van der Giessen WJ,Serruys PW

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Following successful cavotricuspid isthmus (CTI) ablation during typical atrial flutter (AFL), anticoagulation therapy is usually withdrawn. However, potential subsequent atrial fibrillation (AF) in these patients may increase embolic risk in the long term. Embolic rates in this setting have not been clearly...

journal_title：Clinical cardiology

authors： Expósito V,Rodríguez-Entem F,González-Enríquez S,Veiga G,Olavarri I,Olalla JJ

更新日期：2016-06-01 00:00:00

abstract：:Rising costs have reached a point at which physicians must assume a major role in dealing with the cost of medicine. Little information is available regarding actual practice at the community hospital level. In order to develop some insight on this issue, a survey of cardiovascular specialists was conducted regarding ...

journal_title：Clinical cardiology

authors： Vogel JH

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Contrast-induced nephropathy (CIN) is the third cause of acute deterioration of renal function in hospitalized patients. HYPOTHESIS:The purpose of the study was to compare the efficacy of saline infusion, saline infusion plus N-acetylcysteine (NAC), and sodium bicarbonate (SB) infusion to prevent CIN in pat...

journal_title：Clinical cardiology

authors： Castini D,Lucreziotti S,Bosotti L,Salerno Uriarte D,Sponzilli C,Verzoni A,Lombardi F

更新日期：2010-03-01 00:00:00

abstract：:A patient with vasospastic angina who developed myocardial ischemia following ethanol ingestion but not after exercise was described. Myocardial ischemia was evidenced by electrocardiograms (ECGs) and thallium-201 scintigrams. The blood acetaldehyde level after ethanol ingestion was abnormally high. The time course an...

journal_title：Clinical cardiology

authors： Ando H,Abe H,Hisanou R

更新日期：1993-05-01 00:00:00

abstract：:According to the Rosenblueth-Simeone model, the heart rate (HR) is proportional to the sympathovagal balance. The individual proportionality constant is the intrinsic HR, which can be determined only invasively. The percentage low-frequency spectral HR variability power, relative to the low- plus high-frequency spectr...

journal_title：Clinical cardiology

authors： Bootsma M,Swenne CA,Bruschke AV

更新日期：1996-01-01 00:00:00

abstract：INTRODUCTION:Some previous studies have suggested a high prevalence of pulmonary embolism (PE) during exacerbations of chronic obstructive pulmonary disease (ECOPD). The SLICE trial aims to assess the efficacy and safety of an active strategy for the diagnosis and treatment of PE (vs usual care) in patients hospitalize...

journal_title：Clinical cardiology

authors： Jiménez D,Agustí A,Monreal M,Otero R,Huisman MV,Lobo JL,Quezada A,Jara-Palomares L,Hernando A,Tabernero E,Marcos P,Ruiz-Artacho P,Ballaz A,Bertoletti L,Couturaud F,Yusen R,SLICE investigators.

更新日期：2019-03-01 00:00:00

abstract：:This review describes 23 patients with aortic valve stenosis who underwent balloon valvuloplasty during life and had subsequent valve tissue examined at the time of aortic valve replacement or at necropsy. Of 23 stenotic aortic valves, 17 were examined within 30 days (early) after balloon dilation. Of these 94% had no...

journal_title：Clinical cardiology

authors： Waller BF,Dorros G,Lewin RF,King JF,McKay C,van Tassel JW

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:The extracellular matrix tissue of the myocardium importantly contributes to left ventricular (LV) performance. Inherited connective tissue disorders related to the FBN1 gene could involve cardiac interstitium resulting in functional abnormalities. HYPOTHESIS:To disclose a primary involvement of myocardium,...

journal_title：Clinical cardiology

authors： Porciani MC,Giurlani L,Chelucci A,Pepe G,Giusti BH,Brunelli T,Attanasio M,Martinucci P,Fattrori R,Abbatea R,Gensini GF

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:The role of warfarin in anterior ST-segment elevation myocardial infarction (STEMI) complicated by left ventricular (LV) dysfunction in patients treated with primary percutaneous coronary intervention (PCI) and dual antiplatelet therapy is unclear. Warfarin may prevent cardioembolic events but significantly ...

journal_title：Clinical cardiology

authors： Driesman A,Hyder O,Lang C,Stockwell P,Poppas A,Abbott JD

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Variations in the apolipoprotein E (apo E) gene may predict the incidence of coronary artery disease (CAD). However, the correlation between apo E polymorphism and the severity of CAD is still unclear. HYPOTHESIS:Apolipoprotein E polymorphism can predict CAD. METHODS:Used a case-case study of 213 Chinese a...

journal_title：Clinical cardiology

authors： Li SS,Yang J,Li LS,Wang HC

更新日期：2010-06-01 00:00:00

abstract：:Recent clinical investigations have provided new insights into physiologic alterations taking place as heart failure progresses. As a result, new end points may be more relevant to monitor in patients, rather than the classical assessment of severity based on subjective evaluation of functional capacity. Structural ch...

journal_title：Clinical cardiology

authors： Cohn JN

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Recently, electrocardiogram (ECG) criteria have been proposed for the diagnosis of acute myocardial infarction (AMI) in the presence of left bundle-branch block (LBBB). However, clinical experience indicates that such ECG changes indicative of AMI are occasionally noted in clinically stable patients with LBB...

journal_title：Clinical cardiology

authors： Madias JE,Sinha A,Ashtiani R,Agarwal H,Win M,Narayan VK

更新日期：2001-10-01 00:00:00

abstract：:The AFFIRM study showed no clear survival advantage for a rhythm versus rate control strategy in patients with atrial fibrillation (AF). However, rhythm control with antiarrhythmic drugs (AADs) is appropriate in a large number of patients with AF. The American College of Cardiology/ American Heart Association/European...

journal_title：Clinical cardiology

authors： Reiffel JA,Naccarelli GV

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:In this study, we evaluated the feasibility and clinical usefulness of TS(E-E(') ), the time interval between the onsets of early diastolic mitral inflow velocity (E) and mitral annular velocity (E'), obtained by simultaneously tracing E and E', in terms of evaluating diastolic function. METHODS:By the dias...

journal_title：Clinical cardiology

authors： Choi JO,Park SW,Shin DH,Han H,Cho S,Kim JH,Song YB,Lee SC

更新日期：2008-08-01 00:00:00

abstract：:The long-term effects of valve replacement for chronic isolated aortic regurgitation as assessed by first-pass exercise radionuclide angiography have never been reported. We studied 20 males and 5 females before, 15 months postoperatively, and from 29 to 109 (mean 62 +/- 21) months following valve replacement with exe...

journal_title：Clinical cardiology

authors： Lumia FJ,LaManna M,Gonzalez-Lavin L,Maranhao V

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:There are very sparse data on patient outcomes related to the use of extracorporeal membrane oxygenation (ECMO) prior to heart operation in children with congenital heart disease. This study was designed to evaluate this association using the Pediatric Health Information System (PHIS) database. HYPOTHESIS:W...

journal_title：Clinical cardiology

authors： Gupta P,Robertson MJ,Beam BW,Rettiganti M

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND HYPOTHESIS:Japan is an aging society, and the number of nonagenarians with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI) is increasing, but their outcomes have not been determined fully. METHODS:We prospectively enrolled 767 consecutive patients who underwent TAVI in t...

journal_title：Clinical cardiology

authors： Yokoyama H,Tobaru T,Muto Y,Hagiya K,Higuchi R,Saji M,Takamisawa I,Shimizu J,Takanashi S,Takayama M,Tomita H,Tamura H,Doi S,Okazaki S,Isobe M

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Although the outcome of patients with angiographically insignificantly narrowed coronary arteries (INCA) is not clearly defined, such lesions can progress or rupture, thus causing cardiovascular morbidity. Preventive therapy with aspirin and lipid-lowering drugs therefore seems warranted in these patients. ...

journal_title：Clinical cardiology

authors： Henkin Y,Abuful A,Yosefi C,Elis A,Ilia R,Gidron Y

更新日期：2004-06-01 00:00:00

abstract：:Since the initial report of balloon coarctation angioplasty in 1982, several workers used this technique in native coarctation and postoperative recoarctation. Immediate and intermediate-term follow-up results are generally good with a small chance for recoarctation and aneurysmal formation at the site of coarctation....

journal_title：Clinical cardiology

authors： Rao PS

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Intravenous inotropic intervention in congestive heart failure is generally associated with a poor prognosis and is largely used as a "bridge" to mechanical support or heart transplantation. HYPOTHESIS:We hypothesized that the inotropic support afforded by dobutamine may serve as a bridge to the introductio...

journal_title：Clinical cardiology

authors： Levine TB,Levine AB,Elliott WG,Narins B,Stomel RJ

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Left ventricular ejection fraction (LVEF) has shown to predict outcomes in patients with heart failure (HF). Left ventricular recovery (LVR) has shown to improve prognosis. HYPOTHESIS:Guideline-directed medical therapy will predict LVR in patients with HF and reduced LVEF. METHODS:We studied 244 patients w...

journal_title：Clinical cardiology

authors： Valika A,Paprockas K,Villines D,Costanzo MR

更新日期：2018-06-01 00:00:00

abstract：:Several investigators have documented the successful use of oral sustained-release theophylline in treating symptomatic bradycardia and sick sinus syndrome. This paper reports a case of chronotropic incompetence in which specific exercise indices, including the chronotropic response index, were used to measure the the...

journal_title：Clinical cardiology

authors： Dixon WC 4th,Bauch TD

更新日期：2000-10-01 00:00:00