Ethanol-induced myocardial ischemia: close relation between blood acetaldehyde level and myocardial ischemia.

Abstract:

:A patient with vasospastic angina who developed myocardial ischemia following ethanol ingestion but not after exercise was described. Myocardial ischemia was evidenced by electrocardiograms (ECGs) and thallium-201 scintigrams. The blood acetaldehyde level after ethanol ingestion was abnormally high. The time course and severity of myocardial ischemia coincided with those of the blood ethanol and acetaldehyde level. Coronary arteriography showed ergonovine maleate-induced coronary vasospasm at the left anterior descending coronary artery. ECG changes similar to those induced by ethanol ingestion were observed at the same time. These findings suggest that the high blood acetaldehyde level might be responsible for the development of coronary vasospasm and myocardial ischemia in this patient.

journal_name

Clin Cardiol

journal_title

Clinical cardiology

authors

Ando H,Abe H,Hisanou R

doi

10.1002/clc.4960160514

subject

Has Abstract

pub_date

1993-05-01 00:00:00

pages

443-6

issue

5

eissn

0160-9289

issn

1932-8737

journal_volume

16

pub_type

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