Expanding the understanding of the treatment of chronic angina: a 21st century approach-part II.

Abstract:

:Three randomized, clinical trials of the drug ranolazine relate to patients with symptomatic myocardial ischemia. A fourth randomized, controlled, clinical trial compares optimal medical therapy with percutaneous coronary intervention (PCI) plus medical therapy.

journal_name

Clin Cardiol

journal_title

Clinical cardiology

authors

Conti CR

doi

10.1002/clc.20406

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

295-6

issue

7

eissn

0160-9289

issn

1932-8737

journal_volume

31

pub_type

社论
  • Thallium-201 single-photon emission computed tomography: quantitative assessment of left ventricular perfusion and structural change in patients with chronic aortic regurgitation.

    abstract:BACKGROUND:Previously, perfusion defect in the left ventricle was detected by thallium-201 (201T1) single-photon emission computed tomography (SPECT) in aortic regurgitation (AR). The significance of 201T1 SPECT, however, has not been clarified. Limited information is available regarding the relationship between functi...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960281206

    authors: Yasuda H,Taniguchi K,Takahashi T,Sawa Y,Matuda H

    更新日期:2005-12-01 00:00:00

  • Negative U wave during percutaneous transluminal coronary angioplasty.

    abstract::To clarify the clinical significance of the negative U wave during acute myocardial ischemia, the appearance of the U wave and ST-segment elevation on electrocardiography during percutaneous transluminal coronary angioplasty (PTCA) of the left anterior descending artery (LAD group: 11 patients) or right coronary arter...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960140311

    authors: Yano H,Hiasa Y,Aihara T,Nakaya Y,Mori H

    更新日期:1991-03-01 00:00:00

  • Dynamic cardiomyoplasty for treatment of heart failure.

    abstract::Dynamic cardiomyoplasty is a new surgical procedure proposed for treatment of the failing heart. Clinically, the latissimus dorsi muscle is raised as a pedicled flap and wrapped around the heart. The skeletal muscle is transformed to produce a myocardium-like fatigue-resistant muscle. It is stimulated to contract in s...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960121203

    authors: Hill AB,Chiu RC

    更新日期:1989-12-01 00:00:00

  • Hemodynamics and myocardial oxygen metabolism of pulsus alternans in patients with dilative cardiomyopathy.

    abstract::The hemodynamic and myocardial energetic changes due to pulsus alternans were investigated by left and right heart catheterization and by oxygen consumption measurements in three patients with dilative cardiomyopathy. In all three patients, pulsus alternans developed after intravenous administration of the phosphodies...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960100506

    authors: Hasenfuss G,Holubarsch C,Heiss HW,Bonzel T,Funfack M,Revenaugh M,Meinertz T,Just H

    更新日期:1987-05-01 00:00:00

  • Examination of research trends on patient factors in patients with implantable cardioverter defibrillators.

    abstract:BACKGROUND:The implantable cardioverter defibrillator (ICD) is the most effective treatment available for terminating potentially life-threatening ventricular tachycardia and ventricular fibrillation and reducing the risk of mortality. Despite its established health benefits, ICD therapy is accompanied by a unique arra...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.20035

    authors: Stutts LA,Cross NJ,Conti JB,Sears SF

    更新日期:2007-02-01 00:00:00

  • Taking cardiology clinical trials to the next level: A call to action.

    abstract::Physicians previously perceived heart disease to be a man's disease; yet, since 1984, more women have died of ischemic heart disease. Because women who develop obstructive coronary heart disease and heart failure tend to do so 10 years later than men, cardiology clinical trials that use arbitrary age cutoffs or exclus...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.22907

    authors: Clayton JA,Arnegard ME

    更新日期:2018-02-01 00:00:00

  • Hemodynamic-guided heart-failure management using a wireless implantable sensor: Infrastructure, methods, and results in a community heart failure disease-management program.

    abstract:BACKGROUND:The real-world impact of remote pulmonary artery pressure (PAP) monitoring on New York Heart Association (NYHA) class improvement and heart failure (HF) hospitalization rate is presented here from a single center. HYPOTHESIS:METHODS: Seventy-seven previously hospitalized outpatients with NYHA class III HF w...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22643

    authors: Jermyn R,Alam A,Kvasic J,Saeed O,Jorde U

    更新日期:2017-03-01 00:00:00

  • Platelet reactivity in response to loading dose of atorvastatin or rosuvastatin in patients with stable coronary disease before percutaneous coronary intervention: The STATIPLAT randomized study.

    abstract:BACKGROUND:The acute effects of statin loading dose (LD) on platelet reactivity in patients with chronic stable angina (CSA) are not completely clear. HYPOTHESIS:We hypothesized that LDs of atorvastatin and rosuvastatin have different pharmacodynamic acute effects on platelet aggregability in CSA patients with baselin...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/clc.22709

    authors: Godino C,Pavon AG,Mangieri A,Salerno A,Cera M,Monello A,Chieffo A,Magni V,Cappelletti A,Margonato A,Colombo A

    更新日期:2017-08-01 00:00:00

  • Colchicine for large pericardial effusion.

    abstract::On the basis of our reported experience with colchicine for recurrent pericarditis, we administered colchicine to two patients with large pericardial effusions complicating idiopathic pericarditis. The first was a 26-year-old male who showed clinical deterioration following emergency pericardiocentesis and aspirin (3 ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960210220

    authors: Adler Y,Guindo J,Finkelstein Y,Khouri A,Assali A,Bayes-Genis A,Bayes de Luna A

    更新日期:1998-02-01 00:00:00

  • Strategies for managing the patient with acute non-Q-wave myocardial infarction.

    abstract::The prognosis for patients with non-Q-wave myocardial infarction (MI) remains controversial, although a number of studies have shown a less favorable outlook after hospital discharge for patients with non-Q-wave than for those with Q-wave infarction. Numerous management strategies are available to the clinician, many ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:

    authors: Boden WE

    更新日期:1989-07-01 00:00:00

  • Nonatherosclerotic causes of coronary artery narrowing--Part III.

    abstract::Approximately 5% of patients with acute myocardial infarction do not have atherosclerotic coronary artery disease but have other causes for their luminal narrowing. The third part of this three-part review of nonatherosclerotic causes of coronary narrowing focuses on coronary vasculitis, infectious diseases, Kawasaki'...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960190814

    authors: Waller BF,Fry ET,Hermiller JB,Peters T,Slack JD

    更新日期:1996-08-01 00:00:00

  • Partial fatty acid oxidation (pFOX) inhibition: a new therapy for chronic stable angina.

    abstract::During myocardial ischemia, fatty acids are the principal source of energy, increasing myocardial oxygen consumption and making a decrease in coronary blood flow less well tolerated. Increasing glucose oxidation during myocardial ischemia may improve cardiac efficiency. The pFOX inhibitors have the potential to accomp...

    journal_title:Clinical cardiology

    pub_type: 社论

    doi:10.1002/clc.4960260402

    authors: Conti CR

    更新日期:2003-04-01 00:00:00

  • Influence of risk factors on long-term survival following acute myocardial infarction: a follow-up study in central Japan.

    abstract::The long-term survival rate following acute myocardial infarction (AMI) was studied in 358 patients in central Japan who were monitored for 8 to 20 years after discharge from hospital for AMI. Fifteen-year cardiac survival rates were 65% in males and 72% in females. In both sexes, the survival rate decreased with incr...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960120905

    authors: Enomoto N,Yamauchi K,Hayashi H,Saito H,Hamajima N,Sasaki R,Sotobata I,Tanimura H

    更新日期:1989-09-01 00:00:00

  • Neuroleptanalgesia in acute myocardial infarction: effects of hemodynamic parameters and plasma catecholamines.

    abstract::The use of neuroleptanalgesia in acute myocardial infarction offers the possibility of reducing pain and emotional stress. The influence of such treatment on hemodynamic parameters (heart rate, cardiac output, stroke volume, peripheral resistance, systemic blood pressure, and pulmonary pressure) and on the plasma leve...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960040505

    authors: Magometschnigg D,Hörtnagl H,Gassner A,Hammerle AF,Kleinberger G,Lenzhofer R,Lochs H,Pall H,Pichler M

    更新日期:1981-09-01 00:00:00

  • Long-term survival after acute myocardial infarction and relation to type 2 diabetes and other risk factors.

    abstract:BACKGROUND:Diabetes mellitus (DM) is well established as a short-term prognostic indicator after myocardial infarction (MI), but little long-term data are available. HYPOTHESIS:The objective of the study was to assess the impact of DM and other patient characteristics at baseline on long-term mortality after acute MI....

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20776

    authors: Gruppetta M,Calleja N,Fava S

    更新日期:2010-07-01 00:00:00

  • Should interventional cardiac catheterization procedures take place at the time of diagnostic procedures?

    abstract:BACKGROUND:In many cardiac catheterization laboratories interventional procedures are performed at a date later than the diagnostic study, causing increased hospital days and costs. Few data exist which compare procedural success, complications, and costs between procedures performed at the time of diagnostic study and...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960230505

    authors: Panchamukhi VB,Flaker GC

    更新日期:2000-05-01 00:00:00

  • Optimal secondary prevention medication use in acute myocardial infarction patients with nonobstructive coronary artery disease is modified by management strategy: insights from the TRIUMPH Registry.

    abstract:BACKGROUND:Patients with acute myocardial infarction (AMI) and nonobstructive coronary artery disease (nonobCAD) may be perceived to be at lower risk for cardiac events, relative to those with obstructive CAD (obCAD), and thus less likely to receive optimal preventive medications in the year following AMI. HYPOTHESIS:...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/clc.22686

    authors: Pitts R,Daugherty SL,Tang F,Jones P,Ho PM,Tsai TT,Spertus J,Maddox TM

    更新日期:2017-06-01 00:00:00

  • Arrhythmias in Fabry cardiomyopathy.

    abstract:BACKGROUND:Prior studies suggest that the incidence of ventricular arrhythmias is high in patients with Fabry cardiomyopathy. This study evaluated the incidence of significant arrhythmias in a series of patients with Fabry cardiomyopathy. HYPOTHESIS:Arrhythmias are important causes of morbidity and mortality in Fabry ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22047

    authors: Acharya D,Robertson P,Kay GN,Jackson L,Warnock DG,Plumb VJ,Tallaj JA

    更新日期:2012-12-01 00:00:00

  • Acute myocardial infarction with normal coronary arteries. In vivo demonstration of coronary thrombosis during the acute episode.

    abstract::Two cases with acute myocardial infarction are presented. Both had thrombotic occlusion of the infarct-related artery. Following successful thrombolysis with streptokinase, coronary angiography was normal. These cases prove that "myocardial infarction with normal coronaries" can be associated with coronary thrombosis ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960061107

    authors: Fernandez MS,Pichard AD,Marchant E,Lindsay J Jr

    更新日期:1983-11-01 00:00:00

  • Dobutamine as bridge to angiotensin-converting enzyme inhibitor-nitrate therapy in endstage heart failure.

    abstract:BACKGROUND:Intravenous inotropic intervention in congestive heart failure is generally associated with a poor prognosis and is largely used as a "bridge" to mechanical support or heart transplantation. HYPOTHESIS:We hypothesized that the inotropic support afforded by dobutamine may serve as a bridge to the introductio...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960240311

    authors: Levine TB,Levine AB,Elliott WG,Narins B,Stomel RJ

    更新日期:2001-03-01 00:00:00

  • Association of cholesterol levels and occurrence of angiographically detectable endothelial disruption during coronary angioplasty.

    abstract:BACKGROUND:Disruption of the atherosclerotic plaque is a common feature of both acute coronary syndromes and balloon dilatation of coronary artery stenoses. HYPOTHESIS:The study was undertaken to evaluate whether the known association of cholesterol levels and acute coronary syndromes also exists for the occurrence of...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4950260708

    authors: Rubboli A,Euler DE,Sangiorgio P,Casella G,La Vechia L,Fontanelli A,Bracchetti D

    更新日期:2003-07-01 00:00:00

  • Effect of precordial electrocardiographic electrode placement on ST-segment measurement during exercise.

    abstract::Research protocols often utilize serial exercise testing to examine the efficacy of anti-ischemic therapies. These tests, however, are prone to multiple sources of bias. This investigation sought to determine the influence of varying precordial electrocardiographic (ECG) electrode placement on the detection of exercis...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960180409

    authors: Bertolet BD,Boyette AF,Mardis M,Hill JA

    更新日期:1995-04-01 00:00:00

  • QT dispersion plus ST-segment depression: a new predictor of restenosis after successful percutaneous transluminal coronary angioplasty.

    abstract:BACKGROUND:ST-segment depression during exercise testing is frequently observed in the absence of restenosis after percutaneous transluminal coronary angioplasty (PTCA). HYPOTHESIS:With the goal of improving the prediction of restenosis after PTCA, we evaluated the usefulness of ST-segment depression plus QT dispersio...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960220608

    authors: Aytemir K,Ozer N,Aksöyek S,Ozkutlu H,Oto A,Ozmen F

    更新日期:1999-06-01 00:00:00

  • A review of the amyloidoses that infiltrate the heart.

    abstract::Primary amyloidosis, systemic senile amyloidosis, isolated atrial amyloidosis, and transthyretin isoleucine 122 amyloidosis frequently involve the heart. Amyloid fibrils infiltrate the myocardium, impairing ventricular contraction and relaxation. The clinical manifestations of cardiac infiltration in these disorders a...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960210804

    authors: McCarthy RE 3rd,Kasper EK

    更新日期:1998-08-01 00:00:00

  • Initial presenting electrocardiogram as determinant for hospital admission in patients presenting to the emergency department with chest pain: a pilot investigation.

    abstract:BACKGROUND:Evaluation of chest pain accounts for millions of costly Emergency Department (ED) visits and hospital admissions annually. Of these, approximately 10-20% are myocardial infarctions (MI). HYPOTHESIS:Patients with chest pain whose initial electrocardiogram (ECG) is normal do not require hospital admission fo...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20141

    authors: Challa PK,Smith KM,Conti CR

    更新日期:2007-11-01 00:00:00

  • Prolonged low-dose thrombolytic therapy: a novel adjunctive strategy in the management of an infected right atrial thrombus.

    abstract::An 81-year-old man presented with a large, infected right atrial thrombus that was refractory to anticoagulants and several courses of antibiotics. The risk of surgical removal of the thrombus, which was associated with a pacemaker electrode, was considered prohibitive. The patient was treated for 7 days with low-dose...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4950250709

    authors: Chuang S,Mehta RH,Fay WP

    更新日期:2002-07-01 00:00:00

  • Echocardiographic evaluation and clinical implications of aortic stiffness and coronary flow reserve and their relation.

    abstract::The normal human aorta is not a stiff tube but is characterized by elastic properties with a buffering Windkessel function. Aortic stiffening may cause an increase in aortic pulse pressure, left ventricular load, and ultimately left ventricular hypertrophy. This, together with the decreased diastolic transmyocardial p...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.20252

    authors: Nemes A,Geleijnse ML,Forster T,Soliman OI,Ten Cate FJ,Csanády M

    更新日期:2008-07-01 00:00:00

  • Refractory swallowing-induced paroxysmal supraventricular tachycardia.

    abstract::A 51-year-old female with a two-year history of palpitations associated with swallowing was evaluated by intracardiac electrophysiologic studies. Intracardiac recordings documented the presence of an ectopic left atrial focus induced by swallowing with no evidence of accessory pathway conduction. Gastrointestinal eval...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960110117

    authors: Ransbottom JC,Mirro MJ

    更新日期:1988-01-01 00:00:00

  • Lower admission hemoglobin levels are associated with longer symptom duration in acute ST-elevation myocardial infarction.

    abstract:BACKGROUND:An acute-phase response in patients with acute myocardial infarction could contribute to the development of anemia. HYPOTHESIS:An association may exist between symptom duration, hemoglobin (Hb) concentration and serum C-reactive protein (CRP) values in patients presenting to an emergency department (ED) wit...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22215

    authors: Shacham Y,Leshem-Rubinow E,Ben-Assa E,Roth A,Steinvil A

    更新日期:2014-02-01 00:00:00

  • Abnormalities of the S-T segment--Part I.

    abstract::The usual normal S-T segment of the surface electrocardiogram (ECG) contributes little to the diagnostic procedure. When the S-T segment is too long or too short, or when it is displaced upward or downward, it is commonly abnormal. Under such circumstances, an S-T segment abnormality usually contributes considerable d...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960200602

    authors: Hurst JW

    更新日期:1997-06-01 00:00:00