Echocardiographic evaluation and clinical implications of aortic stiffness and coronary flow reserve and their relation.

Abstract:

:The normal human aorta is not a stiff tube but is characterized by elastic properties with a buffering Windkessel function. Aortic stiffening may cause an increase in aortic pulse pressure, left ventricular load, and ultimately left ventricular hypertrophy. This, together with the decreased diastolic transmyocardial pressure gradient interacts with coronary flow and flow reserve. In recent studies, significant correlations between coronary flow reserve and aortic stiffness have been demonstrated in different patient populations. The aim of the present review is to describe the current echocardiographic modalities to measure aortic stiffness and coronary flow reserve and to overview our knowledge about the relationship between aortic stiffness and coronary flow reserve.

journal_name

Clin Cardiol

journal_title

Clinical cardiology

authors

Nemes A,Geleijnse ML,Forster T,Soliman OI,Ten Cate FJ,Csanády M

doi

10.1002/clc.20252

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

304-9

issue

7

eissn

0160-9289

issn

1932-8737

journal_volume

31

pub_type

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