Diabetic heart disease--Part II: The clinical and pathological spectrum.

Abstract:

:Diabetes mellitus is a significant condition, affecting major segments of all population groups studied. With the introduction of insulin and oral hypoglycemic therapy, together with better understanding of diet and weight control gained over the past half century, the primary causes of diabetic morbidity and mortality have shifted in varying proportions from metabolic derangements, infection, and renal insufficiency to different types of cardiovascular disease. Despite extensive clinical and laboratory research on the etiology, pathogenesis, and even the existence of cardiovascular disease associated with diabetes mellitus, however, considerable debate is still apparent in this field. Our purpose is to present an overview of the subject of diabetic heart disease, with a critical analysis of epidemiologic, clinical, and pathological data. Some of this material will be addressed from the perspective of research in this area over the past decade by one of us (SMF), particularly in experimental hypertensive and diabetic cardiomyopathy. However, overall, an attempt will be made to provide an objective and balanced analysis in order to answer the question: does diabetic heart disease exist?

journal_name

Clin Cardiol

journal_title

Clinical cardiology

authors

van Hoeven KH,Factor SM

doi

10.1002/clc.4960121110

subject

Has Abstract

pub_date

1989-11-01 00:00:00

pages

667-71

issue

11

eissn

0160-9289

issn

1932-8737

journal_volume

12

pub_type

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