Abstract：
PURPOSE:To determine the necessity for the heightened level of monitoring for cataract development in patients taking quetiapine (Seroquel, AstraZeneca Pharmaceuticals, Wilmington, Delaware) dictated by the Physicians' Desk Reference. Also, to explore the possibility of cataractogenesis because of quetiapine therapy. DESIGN:Observational case series. METHODS:Data were garnered from a series of 80 case reports collected at the National Registry of Drug-Induced Ocular Side Effects (Portland, Oregon). The World Health Organization (WHO) causality assessment guidelines were used to assess the relationship between quetiapine and cataractogenesis. RESULTS:There were 34 reports of cataracts associated with quetiapine therapy. Average age was 44 years with 23 females and 11 males studied. Average duration of therapy was 29.3 weeks on standard doses. CONCLUSIONS:Cataractogenesis secondary to quetiapine is "unlikely" by WHO guidelines. This probably makes it unnecessary to require biannual ophthalmic examinations as routine eye examinations are sufficient to screen for this condition.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Fraunfelder FWdoi
10.1016/j.ajo.2004.05.038subject
Has Abstractpub_date
2004-11-01 00:00:00pages
870-1issue
5eissn
0002-9394issn
1879-1891pii
S0002-9394(04)00557-4journal_volume
138pub_type
杂志文章abstract：:Four patients (three men, 68, 35, and 33 years old, and one woman, 46 years old) had central serous elevation of the macula with abnormal latency of the visual-evoked potential and spontaneous Pulfrich phenomenon. In three instances both the electrophysiologic test and the clinical Pulfrich test reverted to normal on ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(85)90684-1
更新日期：1985-10-15 00:00:00
abstract：PURPOSE:The effectiveness of diffusion trace value analysis for non-invasive assessment of retinal ganglion cell (RGC) axonal degeneration at multiple anatomic levels along the human visual pathway under clinical setting was evaluated. DESIGN:Imaging study. METHODS:Ten patients with unilateral chronic optic neuropath...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.05.042
更新日期：2006-10-01 00:00:00
abstract：:Glycogen, adenosine triphosphate, and hydration were measured in rabbit corneal epithelium to determine whether the corneal epithelium glycogen decrease, increase in epithelial hydration, and decrease in epithelial adenosine triphosphate stores, seen as a result of contact lens wear, were secondary only to anoxia or m...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90884-3
更新日期：1975-07-01 00:00:00
abstract：PURPOSE:To estimate the cumulative probability of Nd:YAG laser posterior capsulotomy after cataract extraction in a geographically defined population. METHODS:Rochester Epidemiology Project databases were used to identify retrospectively all Nd:YAG laser posterior capsulotomies performed on Olmsted County, Minnesota, ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00795-9
更新日期：2001-02-01 00:00:00
abstract：PURPOSE:To report angiographically documented cystoid macula edema associated with the use of each of the three newly available ocular hypotensive lipids: unoprostone, travaprost, and bimatoprost. DESIGN:Observational case series. METHODS:Retrospective review of three patients in a clinical practice who had uncontrol...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)01411-8
更新日期：2002-03-01 00:00:00
abstract：PURPOSE:To report a case of horizontal diplopia after a four-lid blepharoplasty. DESIGN:Observational and interventional case report. METHODS:Analysis of the history and management of a 64-year-old man who underwent a four-lid blepharoplasty, after which he developed horizontal diplopia. RESULTS:The patient was foun...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.11.045
更新日期：2006-04-01 00:00:00
abstract：:A new sorting test requires only two minutes for quantitative estimation of saturation thresholds for bluish pigment colors. The test is highly sensitive to and specific for differences between normal subjects and individuals with acquired color vision defects. When combined with Ishihara's pseudo-isochromatic plates,...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(81)90781-9
更新日期：1981-08-01 00:00:00
abstract：PURPOSE:To describe optical coherence tomographic (OCT) angiography findings in chronic central serous chorioretinopathy (CSC), and to characterize their OCT B-scans by means of the split-spectrum amplitude-decorrelation angiography algorithm. DESIGN:Evaluation of an imaging technique in a cohort of patients. METHODS...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2015.06.016
更新日期：2015-09-01 00:00:00
abstract：:With a recently developed technique for quantifying the geometry of the anterior chamber in optical cross section (slit-lamp photography using the Scheimpflug principle and computer correction for the optical effects of the cornea), we studied the iris contour before and after iridotomy in six patients with narrow ant...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76341-x
更新日期：1990-09-15 00:00:00
abstract：PURPOSE:To compare the efficacy and visual results of phacoemulsification vs manual sutureless small-incision extracapsular cataract surgery (SICS) for the treatment of cataracts in Nepal. DESIGN:Prospective, randomized comparison of 108 consecutive patients with visually significant cataracts. METHODS:settings: Outr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2006.07.023
更新日期：2007-01-01 00:00:00
abstract：:Of 59 patients with traumatic hyphema studied prospectively, 32 received aminocaproic acid, an antifibrinolytic agent, to prevent secondary hemorrhage. The remaining 27 patients received placebo in an identical manner. Of the aminocaproic acid-treated patients, only one (3%) rebled, while nine patients (33%) receiving...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0002-9394(76)90254-3
更新日期：1976-03-01 00:00:00
abstract：PURPOSE:Transvascular leakage occurs in diabetic retinopathy. The tight junction proteins occludin and zonula occludens-1 (ZO-1) and adherens junction protein cadherin-5 are critical to the maintenance of endothelial barrier. We report a comparison of junction protein expression in the normal and diabetic retina. METH...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00323-2
更新日期：2000-02-01 00:00:00
abstract：:Benign lateral rectus palsy developed in two adults, a 62-year-old man and a 56-year-old woman. Both were hospitalized because of headache and diplopia. Extensive laboratory and neurologic testing showed no abnormalities except leukopenia (the white blood cell count was 2,600 cells/mm3 in one patient and 3,100 cells/m...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(82)90254-9
更新日期：1982-10-01 00:00:00
abstract：PURPOSE:To describe the minimum inhibitory concentration (MIC) of fungal isolates to natamycin and voriconazole, and to compare these MICs to previous ocular susceptibility studies. DESIGN:Experimental laboratory study using isolates from a randomized clinical trial. METHODS:The Mycotic Ulcer Treatment Trial I was a ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ajo.2013.10.004
更新日期：2014-02-01 00:00:00
abstract：:Ten patients with endogenous uveitis were in clinical remission attributable to treatment with cyclosporine and prednisone. After the cyclosporine dose was reduced by two thirds, these patients were randomly assigned to treatment with or without ketoconazole, a potent inhibitor of cytochrome P-450, in a double-masked ...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9394(14)74795-6
更新日期：1992-06-15 00:00:00
abstract：PURPOSE:To assess the relative distribution in the cornea of amyloid and (beta)ig-h3 gene product in lattice corneal dystrophy type IIIA (LCD-IIIA). METHODS:Serial sections from the cornea of a patient with LCD-IIIA were subjected to either Congo red staining or immunohistochemistry employing an antibody to (beta)ig-h...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00360-2
更新日期：1999-04-01 00:00:00
abstract：:We have constructed an ophthalmic fixation device that stabilizes an enucleated eye, and helps both in the pathologic examination of the eye and in ophthalmic practice surgery. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74929-3
更新日期：1980-09-01 00:00:00
abstract：:We implanted nine intraocular lenses for the aphakic correction of congenital monocular cataracts in eight children (eight eyes). During follow-up periods ranging from 18 to 50 months in six children, there were no major complications connected to the surgery. Parental cooperation with treatment for amblyopia was sati...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)77820-1
更新日期：1983-09-01 00:00:00
abstract：PURPOSE:To assess and compare the frequency of reflex sneezing occurring during periocular anesthetic injections with and without intravenous sedation. DESIGN:Retrospective, comparative case series. METHODS:Seven hundred and twenty-two patients undergoing oculoplastic surgical procedures were included in this study. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.02.013
更新日期：2008-07-01 00:00:00
abstract：PURPOSE:To determine if there are variations in regional practice patterns for retinal detachment repair in the United States. DESIGN:Retrospective, noninterventional, cross-sectional study. METHODS:Year 2009 Medicare fee-for-service claims for retinal detachment repair were aggregated in 4 geographic regions and eva...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.11.034
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:To report a case of an occult, metallic, anterior-chamber intraocular foreign body after uneventful phacoemulsification that was masquerading as chronic recalcitrant postoperative inflammation. DESIGN:Interventional case report. METHODS:A 73-year-old patient was referred to us for recalcitrant anterior-chambe...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.08.031
更新日期：2005-03-01 00:00:00
abstract：PURPOSE:To compare the prevalence of keratoconjunctivitis sicca (KCS) in a prospective cohort of 22,382 diabetic patients with that in the general population. DESIGN:Prospective, observational, cohort study. METHODS: SETTING:A district of israel's largest health maintenance organization. STUDY POPULATION:We followe...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.10.022
更新日期：2005-03-01 00:00:00
abstract：:We evaluated whether the rate of occurrence of glaucomatous disk damage in eyes with an optic disk hemorrhage differed from the rate of occurrence in control eyes. We compared 24 patients with a disk hemorrhage to 24 control patients, who had been matched for diagnosis, disk appearance, and visual fields. Cup volume a...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74272-2
更新日期：1987-04-15 00:00:00
abstract：PURPOSE:To compare the effect of age, sex and generation on physician practice patterns in Ontario, Canada. DESIGN:Retrospective cohort study. METHODS:Physician and patient data from 1992-2013 were used to calculate the yearly number of physicians, distinct patients seen, patient visits, government payments, physicia...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2019.04.006
更新日期：2019-09-01 00:00:00
abstract：:We developed a method that models the effect of irregular corneal surface topography on corneal optical performance. A computer program mimics the function of an optical bench. The method generates a variety of objects (single point, standard Snellen letters, low contrast Snellen letters, arbitrarily complex objects) ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74602-1
更新日期：1990-04-15 00:00:00
abstract：PURPOSE:To evaluate the effect of macular reticular pseudodrusen on retinal function using multiple imaging methods. DESIGN:Prospective cross-sectional study. METHODS:Thirteen eyes with reticular pseudodrusen, but without any other macular abnormality or glaucoma, and 20 normal eyes were evaluated. All subjects under...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.06.036
更新日期：2013-12-01 00:00:00
abstract：PURPOSE:To determine the frequency of retinal thickening (RT) in eyes with iridocyclitis and to examine the correlations among anterior chamber (AC) inflammation, RT, and visual acuity. DESIGN:Retrospective, observational case series. METHODS:Records were reviewed of patients seen at the Duke University Eye Center Uv...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2009.03.034
更新日期：2009-09-01 00:00:00
abstract：PURPOSE:To report the efficacy of an aggressive systematic regimen for the treatment of acute nonarteritic central retinal artery occlusion (CRAO). METHODS:Eleven patients who had unilateral CRAO with symptoms of fewer than 48 hours' duration were treated with an aggressive stepwise systematic regimen until retinal ci...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00359-1
更新日期：1999-12-01 00:00:00
abstract：:We developed a method to quantify the surface contour of the peripapillary nerve fiber layer from simultaneous stereoscopic videographic images. Parameters that describe this contour are defined and compared to standard optic nerve structural parameters (cup/disk ratio, disk rim area, cup volume) in three age-matched ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73308-2
更新日期：1989-10-15 00:00:00
abstract：PURPOSE:To use micro-ribonucleic acid (microRNA) profiles in the vitreous for differential diagnosis of primary vitreoretinal lymphoma and uveitis. DESIGN:Prospective cross-sectional study. METHODS:This prospective cross-sectional study included 17 diffuse large B-cell primary vitreoretinal lymphoma and 12 uveitis pa...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.12.014
更新日期：2014-03-01 00:00:00
