Abstract:
:This Working Group was assembled to review and evaluate methods currently used to estimate work site exposures to biological agents and to present recommendations on suitable measurement strategies. The current state of exposure assessment was evaluated for environments with organic dust including agriculture, composting, sewage and waste treatment processing, peat moss harvesting and handling, cotton and textile processing, greenhouse work, and grass seed processing. Methods for measurement of microbial contaminants in indoor environments were also considered. Important methods are emerging that use quantitative PCR for assessment of microbial agents. Difficulties exist with optimization of extraction to yield contaminant-free DNA without significant DNA loss. Advances in assays for microbial agents (e.g., endotoxin and glucans) as well as allergens have increased the utility of exposure assessment for these agents. A crucial area for further development is international harmonization of methodologies to reduce interlaboratory variability and to facilitate establishment of exposure guidelines. Endotoxin exposure assessment using the Limulus amebocyte lysate method is a high priority for harmonization because of its importance as a pulmonary inflammatory agent in many occupational settings.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Thorne PS,Duchaine C,Douwes J,Eduard W,Górny R,Jacobs R,Reponen T,Schierl R,Szponar Bdoi
10.1002/ajim.20066subject
Has Abstractpub_date
2004-10-01 00:00:00pages
419-22issue
4eissn
0271-3586issn
1097-0274journal_volume
46pub_type
杂志文章abstract:BACKGROUND:Concern regarding functioning and effectiveness of joint health and safety committees (JHSCs) in Ontario hospitals was raised following the Severe Acute Respiratory Syndrome outbreak in 2003. A subsequent literature review revealed a lack of studies focused within the healthcare sector. METHODS:A tool to me...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22703
更新日期:2017-04-01 00:00:00
abstract::This study measured the validity of work histories obtained by interview with 84 female workers and examined specific factors which influence such validity. This is the first validation of work histories collected by interviews with women. The validity of each interview was assessed over a period of 29 years, from 195...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700190409
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVES:To assess changes in work characteristics, socioeconomic status inequalities in changes in work characteristics, and whether US workplaces are becoming more stressful. METHODS:We analyzed data from 5361 employed participants from the 2002, 2006, 2010, and 2014 NIOSH Quality of Work Life Surveys, based on re...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22971
更新日期:2019-06-01 00:00:00
abstract::A 5-year prospective analysis tests the hypothesis that coal miners who have impaired respiratory health also experience greater numbers of disability days due to occupational injury. Occupational and respiratory health information collected for the period 1977 through 1981 by the National Institute for Occupational S...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700070409
更新日期:1985-01-01 00:00:00
abstract::Recent epidemiological and experimental work confirms that inorganic lead compounds are associated with increased risks of tumorigenesis. In animals, these risks can be induced at doses that are not associated with organ toxicity and in mice that do not produce alpha-2 urinary globulin in the kidney. Thus the mechanis...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/1097-0274(200009)38:3<316::aid-ajim11>3.0.
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Diesel exhaust is considered a probable human carcinogen by the International Agency for Research on Cancer (IARC). The epidemiologic evidence rests on studies of lung cancer among truck drivers, bus drivers, shipyard workers, and railroad workers. The general public is exposed to diesel exhaust in ambient a...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199809)34:3<220::aid-ajim3
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:Many newly constructed green buildings (GB) are certified using the United States Green Building Council (USGBC) Leadership in Energy and Environmental Design (LEED) rating system for new construction and major renovation which focuses on architectural and mechanical design to conserve energy, reduce environ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22166
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:Assess the national prevalence of current workplace exposure to potential skin hazards, secondhand smoke (SHS), and outdoor work among various industry and occupation groups. Also, assess the national prevalence of chronic workplace exposure to vapors, gas, dust, and fumes (VGDF) among these groups. METHODS:...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22089
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Occupational eye injuries have been recognized as a serious health risk to workers and are in need of further investigation to develop effective interventions. METHODS:Rhode Island workers' compensation claims of ocular injury between 1998 through 2002 (n=8,877) were examined. The Current Population Survey ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20234
更新日期:2006-01-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10273
更新日期:2003-10-01 00:00:00
abstract::Attention to psychosocial hazards in work environments should become an increasingly important component of occupational safety and health interventions. Research findings have linked a number of measurable psychosocial characteristics with negative psychological and physiological consequences. Some serious physical h...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0274(199604)29:4<308::AID-AJIM6
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND:This study estimates the annual cost of alcohol-related injuries to employers in 1998-2000. METHODS:Incidence was estimated with occupational injury data, motor vehicle crash data and health care data for 1998-2000. Employer costs were estimated from federal estimates of injury costs by source of payment us...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20425
更新日期:2007-02-01 00:00:00
abstract::This study examines the determinants of susceptibility to the irritant effects of sodium borate in 18 responsive workers identified through repeated self-reports of nasal irritation. For each worker, susceptibility was characterized by two features; reactivity and sensitivity, as estimated from the slope and intercept...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199812)34:6<614::aid-ajim1
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:A medical screening program began in 1986 for sheet metal workers exposed to asbestos, primarily while working alongside insulators applying spray-on asbestos materials, a practice banned in 1973. Exposure continues during maintenance, renovation, and repair. METHODS:Radiographic abnormalities among 26 397 ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22998
更新日期:2019-07-01 00:00:00
abstract::The methodological choices being made in current worker notification programs are influenced in both obvious and subtle ways by certain ground-breaking notifications carried out during the 1970s and 1980s. A lore has built up concerning these cases. Their names are heavy with implied meaning. As worker notification ga...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700230104
更新日期:1993-01-01 00:00:00
abstract::A retrospective exposure assessment study in the automotive parts industry conducted in conjunction with a cancer mortality and respiratory morbidity study [Kennedy et al. (1989): Am J Ind Med 15:627-641; Eisen et al. (1992): Am J Ind Med 22:809-824; Tolbert et al. (1992): Scand J Work Environ Health 18:351-360] descr...
journal_title:American journal of industrial medicine
pub_type: 历史文章,杂志文章
doi:10.1002/ajim.4700260505
更新日期:1994-11-01 00:00:00
abstract::Formaldehyde is commonly accepted to be an allergen and irritant. However, specifically diagnosed occupational respiratory diseases caused by formaldehyde are relatively rare. Occupational laryngitis was diagnosed in a 47-year-old dairy foreman. He had been exposed for 9 years to formaldehyde emitted from a milk-packi...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1097-0274(199603)29:3<275::AID-AJIM7
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:Occupational exposure to vinyl chloride monomer (VCM) has been established as a cause of hepatocellular carcinoma (HCC) and liver angiosarcoma (ASL). However, some controversy remains due to conflicting results on liver cirrhosis, and to evidence on HCC based on few confirmed cases. The aim of the study is t...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22922
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Investigations of breast cancer among men may provide clues for environmental and occupational risk factors that may be difficult to study in women, because of confounding or effect modification from reproductive female characteristics. The objective was to estimate occupation-specific risks of male breast c...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/1097-0274(200103)39:3<276::aid-ajim1015>3.
更新日期:2001-03-01 00:00:00
abstract::To clarify the effects of lead on autonomic and central nervous system functions, electrocardiographic R-R interval variability (CVRR) as well as visual and brainstem auditory evoked potentials (VEP and BAEP) were measured in 36 female workers exposed to lead (exposed group) and in 15 female textile workers (unexposed...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700280208
更新日期:1995-08-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22912
更新日期:2018-11-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
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更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:Experimental and clinical evidence suggest that stress can lead to ill-health through the disregulation of the hypothalamic-pituitary-adrenal (HPA) axis. Studies to date have produced equivocal results likely due to different methodologies and failure to account for confounding factors. This investigation ai...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20659
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:This study investigated the relationship between weekly working hours and the occurrence of cerebro-cardiovascular diseases using a case-crossover study design. METHODS:We investigated average working hours during the 7 days before the onset of illness (hazard period) and average weekly working hours betwee...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22688
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Pain and fatigue are commonly associated with work-related upper extremity disorders. Occasionally these symptoms persist beyond a reasonable healing period. One potential explanation for prolonged symptom expression is the concurrent development of a stress-mediated illness or CMI (Chronic Multi-Symptom Ill...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.10068
更新日期:2002-05-01 00:00:00
abstract::Surveillance of cause-specific mortality patterns by occupation and industry through the use of death certificate records is a simple and relatively inexpensive approach to the generation of leads as to potential occupational disease problems. Researchers from the National Institute for Occupational Safety and Health ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.4700110309
更新日期:1987-01-01 00:00:00
abstract::A cross-sectional prevalence study of 120 public school custodians was carried out. The purposes were 1) to investigate the prevalence of asbestos-related disease in a group of custodians at risk for asbestos exposure in public schools and 2) to determine the proportion with disease attributable to exposures in school...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700190305
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Small retail businesses experience high robbery and violent crime rates leading to injury and death. Workplace violence prevention programs (WVPP) based on Crime Prevention Through Environmental Design reduce this risk, but low small business participation limits their effectiveness. Recent dissemination mod...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22436
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:There are relatively few studies of large national databases that contain information on working hours and health. The current study involved an analysis of data from a quality of work life (QWL) module developed for the 2002 General Social Survey. This module collected work and health data from a representa...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20388
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Neck pain is a prevalent musculoskeletal condition among workers in the United States. This study explores a set of workplace psychosocial and organization-related factors for neck pain. METHODS:Data used for this study come from the 2010 National Health Interview Survey which provides a representative samp...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22602
更新日期:2016-07-01 00:00:00