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Neural mechanisms in hypertension and the elderly.

Abstract：

:Experimental animal studies carried out over the past 40 years have unequivocally shown that neurogenic mechanisms are involved in the pathogenesis of hypertension. The results of these studies also suggest that neural factors are important not only in the development but also in the maintenance of the high blood pressure condition. Whether this is the case also for human hypertension has been matter of debate for several decades. However, recent studies in man by employing sophisticated techniques for assessing sympathetic tone, i.e. the norepinephrine radiolabelled technique and microneurographic recording of sympathetic nerve traffic, support the hypothesis that alterations in sympathetic modulation of the cardiovascular system take place in hypertension and may have a pathogenetic relevance in age-related blood pressure increase.

journal_name

Arch Gerontol Geriatr

journal_title

Archives of gerontology and geriatrics

authors

Grassi G,Cattaneo BM,Bolla GB,Mancia G

doi

10.1016/0167-4943(94)00609-b

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

79-85

issue

1

eissn

0167-4943

issn

1872-6976

pii

016749439400609B

journal_volume

20

pub_type

杂志文章

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