Abstract：
:Our study aimed to compare cognitive status and declines in AD with/without small vessel disease (SVD) and SIVD at baseline and 1-year follow-up. Patients with Alzheimer's disease without small vessel disease (AD(-)SVD) (n=148), Alzheimer's disease with small vessel disease (AD(+)SVD) (n=94) and SIVD (n=60) were recruited from database of multiple centers in Korea. Basic demographics and detailed neuropsychological results were compared. AD, regardless of SVD, showed worse memory and better executive function than SIVD at baseline. Mini-Mental State Examination scores and visual memory function declined more in AD than those in SIVD whereas Barthel Activities of Daily Living (B-ADL) scores declined more in SIVD. AD showed different patterns of cognitive impairment compared with SIVD. After 1 year, AD showed more rapid cognitive decline in some domains. Further investigations with longer follow-up duration may be needed to confirm the cumulative effects of SVD in AD and different patterns of decline between AD and SIVD.
journal_name
Arch Gerontol Geriatrjournal_title
Archives of gerontology and geriatricsauthors
Hong YJ,Yoon B,Shim YS,Han IW,Han SH,Park KH,Choi SH,Ku BD,Yang DWdoi
10.1016/j.archger.2013.11.005subject
Has Abstractpub_date
2014-05-01 00:00:00pages
415-9issue
3eissn
0167-4943issn
1872-6976pii
S0167-4943(13)00175-1journal_volume
58pub_type
杂志文章abstract：:It is well established that cerebral white matter lesions (WML), present in the majority of older adults, are associated with cardiovascular and cerebrovascular diseases and also with cognitive decline. However, much less is known about how WML are related to other important individual characteristics and about the ge...
journal_title：Archives of gerontology and geriatrics
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abstract：BACKGROUND:Depression, anxiety, and cognitive impairments occur in up to 40 % of adults with AF and are associated with poorer health-related quality of life (HRQoL) and higher symptom burden. However, it is unknown how often these impairments co-occur, or multimorbidity, and how multimorbidity effects HRQoL and sympto...
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abstract：:We studied the change in personal ability to perform the activities of daily living (P-ADL) one year after hospitalization (T2) of patients at least 65 years old at baseline (T1). The study included 363 (175 men) medical inpatients with age range 65-98 (mean 80.2, SD 7.5) years. Information was collected at baseline a...
journal_title：Archives of gerontology and geriatrics
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abstract：:Falls among the elderly is a major public health concern. There has been recent extensive research on the effects of Tai Chi in fall prevention among the elderly. As such, we undertook a systematic review to look for evidence on the effect of this intervention. There were seven randomized controlled trials, which met ...
journal_title：Archives of gerontology and geriatrics
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abstract：:The purpose of this study was to evaluate the validity and reproducibility of the modified lateral functional reach (FR), and to examine the associations between a variety of functional variables and the FR in community-dwelling older people (>65 years of age). A total of 383 aged Japanese participated in this study a...
journal_title：Archives of gerontology and geriatrics
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doi：10.1016/j.archger.2005.06.010
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abstract：:The elderly show a loss of both the intellectual functions and of motion ability. This happens also without particular pathologies; possible tests to highlight this loss are the Mini Mental State Examination (MMSE), and the Functional Reach (FR)-test. During 2004-2005 winter 50 healthy subjects were analyzed; the subj...
journal_title：Archives of gerontology and geriatrics
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journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(94)00578-u
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abstract：:Older adults with joint pain and comorbidity are especially at risk of becoming functionally impaired. Therefore, we studied the frequency and severity of functional limitations and identified potential modifiable determinants that may reduce functional limitations. A prospective cohort study of older adults (≥65 year...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2014.02.006
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journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/s0167-4943(00)00088-1
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journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2009.09.006
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journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2011.09.011
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abstract：:Though frailty status has recently been linked to poorer quality of life, the impact of income on this relationship has not previously been investigated. Data from a population-based panel study, the English Longitudinal Study of Aging, on 3225 participants aged 65-79 years were analyzed cross-sectionally. A Frailty I...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2013.12.008
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abstract：BACKGROUND:Hemodialysis patients in Japan are aging, but the influence of lifestyle factors on EuroQoL 5-Dimension 5-Level (EQ-5D-5 L) scores in older hemodialysis patients is unclear. This study aimed to measure health-related quality of life using the EQ-5D-5 L for older hemodialysis patients and to identify the life...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章,评审
doi：10.1016/j.archger.2018.06.006
更新日期：2018-01-01 00:00:00
abstract：:Increasing evidence indicates that inflammation has a substantial role in the pathogenesis and progression of AD. RDW, a measure of heterogeneity in the size of circulating erythrocytes, is associated with inflammatory markers in many numerous diseases. Present study was undertaken to assess the interrelationships bet...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2012.10.002
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:To investigate the association between frailty and a summary cardiovascular risk measure (Framingham Risk Score, FRS) in a sample of older adults from different epidemiologic contexts participating in the multicenter International Mobility in Aging Study (IMIAS). MATERIAL AND METHODS:This cross-sectional stu...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2020.104279
更新日期：2021-01-01 00:00:00
abstract：BACKGROUND:Research indicates that self-care affects lifestyle and health behaviors; however, little is known about whether or not self-care affects medical utilization. OBJECTIVES:Exploring the effects on self-care behaviors to medical utilizations by elderly with chronic conditions. METHOD:Data from the Taiwanese N...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2015.01.014
更新日期：2015-05-01 00:00:00
abstract：:Because of chronicity and poor environments, elderly leprosy survivors might be at greater risk of developing obesity and sarcopenia than healthy individuals. This study aimed to investigate whether body composition and the prevalence of obesity and sarcopenia among elderly leprosy survivors with no or mild physical i...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2013.07.013
更新日期：2014-01-01 00:00:00
abstract：:Procedures for the estimation of the four parameters of a new mathematical model of survival and mortality kinetics are given. A formulation of the model has been found which had the advantage of maintaining three of four parameters independent of the unit chosen for the age; in addition, two of these parameters have ...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(86)90015-4
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abstract：:The central question in the field of experimental gerontology is: what is biological aging? It is true that a living body must obey the laws of causal determinism; like all bodies it is subject to the physical and chemical laws of the phenomenal world. But there is a further aspect; as well as the finality which unite...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章,评审
doi：10.1016/0167-4943(88)90005-2
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abstract：:Nutritional status is important to elders to live without disabilities. Food Insecurity (FI) is a risk factor associated with poorer nutritional status among elderly as well as a social determinant. This research aimed to identify FI prevalence and to explore the relation between FI, weight status and socio-demographi...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2018.06.004
更新日期：2018-01-01 00:00:00
abstract：:The influence of dementia on the prevalence of urinary and faecal incontinence was investigated in a random sample (n = 485) of the total population of 85-year-olds from the city of Gothenburg, Sweden. The subjects were assessed by a psychiatric interview, physical examinations, computed tomography of the head and ana...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(94)90021-3
更新日期：1994-07-01 00:00:00
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journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2010.01.018
更新日期：2011-01-01 00:00:00
abstract：OBJECTIVES:To investigate the prevalence of potentially inappropriate prescribing (PIP) of central nervous system and psychotropic (CNS-PS) drugs to the Korean elderly population, and to identify PIP-associated factors. METHODS:Ambulatory care visits were identified from the 2013 National Aged Patient Sample (HIRA-APS...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2017.08.013
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abstract：:A representative sample of non-institutionalized elderly persons between 65 and 74 years living in Stockholm county, Sweden responded to a self-report health questionnaire. Special life events and their subsequent effects were examined in the context of health attitudes and health behavior. Of the 370 respondents, 128...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(96)00716-9
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abstract：:Vital statistics data previously published by the Registrar General of England and Wales have been separated into male and female deaths in 1960-69 aged 100, 1961-70 aged 101, 1962-71 aged 102 etc., to represent cohorts of 292 male and 1463 female centenarians born in 1859-1869. Mortality is fitted to age by the metho...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(85)90003-2
更新日期：1985-10-01 00:00:00
abstract：:The present work was designed to study the effect of aging on some parameters of the glutamatergic, aminergic and cholinergic neurotransmission, in the main brain areas of mice of the long-surviving BALB/c-nu strain. We have assayed: (1) the density of three ionotropic receptors for excitatory aminoacids (EAA) which s...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/s0167-4943(00)00057-1
更新日期：2000-06-01 00:00:00
abstract：BACKGROUND:Frailty is a clinical state of increased vulnerability from aging-associated decline. We aimed to determine if a Thai Frailty Index predicted all-cause mortality in community-dwelling older Thais when accounting for age, gender and socioeconomic status. METHODS:Data of 8195 subjects aged 60 years and over f...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2018.05.002
更新日期：2018-01-01 00:00:00
abstract：:Human skin is not able to biosynthesize gamma-linolenic acid (GLA, 18:3omega6) from the precursor linoleic acid (LA), or arachidonic acid (AA) from dihomo-gamma-linolenic acid (DHGLA). Dietary supplementation with GLA-rich seed oil of borage skips the step of hepatic 6-desaturation of fatty acids (FA) and, therefore, ...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/s0167-4943(00)00046-7
更新日期：2000-03-01 00:00:00
abstract：:This study tried to emphasize the significance of statistical data (incidence rate) considering Alzheimer dementia (AD) because variations in incidence and types of dementias do exist in different countries. The data of persons living in two homes (elderly people and psychiatric patients) were overviewed together with...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(95)00644-z
更新日期：1995-07-01 00:00:00
abstract：:Falls in nursing home residents are associated with a significant individual and socioeconomic burden of disease. To trigger and tailor individual intervention programs, solid early detection measures of residents at risk are needed. Aim of this study was thus to test the capability of a free field gait analysis insol...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2020.104294
更新日期：2020-11-11 00:00:00
