Abstract：
:The epidemiologic data on smoking in association with Parkinson disease (PD) is puzzling. A lower incidence of smoking-related malignancies, especially lung cancer, has been reported by several studies in the patients with PD. In this study, we investigated polymorphic variations in the vascular endothelial growth factor (VEGF) gene, which has been proposed having a pivotal role in progressive damage of nigral dopaminergic neurons, between Korean patients with 188 PD and 321 lung cancer patients. There were no significant differences in the tested single-nucleotide polymorphisms (SNPs) between patients with PD and lung cancer; however, one haplotype was significantly different in comparisons between the two diseases. These results suggest that VEGF genetic polymorphisms might help understand the low incidence of lung cancer in the patients with PD.
journal_name
Arch Gerontol Geriatrjournal_title
Archives of gerontology and geriatricsauthors
Kim JS,Yim SV,Koh IS,Choi JS,Yoo JY,Lee KS,Lim Y,Lee KHdoi
10.1016/j.archger.2008.02.007subject
Has Abstractpub_date
2009-05-01 00:00:00pages
287-90issue
3eissn
0167-4943issn
1872-6976pii
S0167-4943(08)00050-2journal_volume
48pub_type
杂志文章abstract：:This study has been carried out to investigate the level of loneliness, determine the level of dependence in the ADL and influential factors in the elderly people. This descriptive, cross-sectional study was conducted in 5 Family Healthcare Centers (FHC) located in central Erzincan, Turkey between March and June 2010....
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章,多中心研究
doi：10.1016/j.archger.2011.03.011
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Older adults show greater postural instabilities under misleading visual cues relative to younger adults. We investigated the effects of age-related visual dependence on motor performance under increased attention demands by adding a motor task and visual stimulus to the Timed Up and Go (TUG) test sub-compon...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2019.104004
更新日期：2020-01-01 00:00:00
abstract：:Leisure time represents an important part of the so-called 'successful aging' and contributes to overcome the problems related to the reduction of the social roles, favoring a better subjective adaptation to old age. In this work we observed the elderly population frequenting our Day Hospital, by estimating the affect...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/s0167-4943(01)00111-x
更新日期：2001-09-01 00:00:00
abstract：OBJECTIVES:To investigate the interrelationships between central obesity, sarcopenia and nutritional status in the elderly. METHODS:We enrolled 501 elderly (women: 47.5 %) with complete datasets. Biochemical and anthropometric data were measured after an overnight fast. Basic characteristics, psychosocial and behavior...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2019.104003
更新日期：2020-01-01 00:00:00
abstract：:In an obese hypertensive woman affected by angina-like chest pain, a physical training program and a low caloric diet resulted in a notable improvement of the anthropometric indexes, hyperinsulinemia, myocardial perfusion and left ventricular mass. ...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(96)86995-0
更新日期：1996-01-01 00:00:00
abstract：:The personal and societal impact of age-related cognitive decline supports the development of effective interventions. While some strategies, such as cognitive training, exercise or socio-intellectual engagement, appear beneficial, few studies have examined the association between personality and intervention efficacy...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2019.103992
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:As one of the leading causes of death around the world, suicide is a global public health threat. Due to the paucity of systematic studies, there exist vast variations in suicide ideation, attempts and suicide rates between various regions of Chinese aging communities. OBJECTIVES:Our systematic study aims t...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章,评审
doi：10.1016/j.archger.2013.05.006
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:The idea that cumulative levels of stress can have deleterious effects on health and longevity has led investigators to discuss individual differences in the accumulation of Allostatic Load (AL) during life. Our aim was to evaluate the AL indices and stress biomarkers between genders and to determine which f...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2019.104006
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:To design and validate a predictive BIA equation to estimate ASM in a sample of non-Caucasian older people and to explore the accuracy of two previous single-frequency BIA published equations. METHOD:This is a cross-sectional study in 213 physically-independent and apparently healthy older men and women subj...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2015.03.007
更新日期：2015-07-01 00:00:00
abstract：OBJECTIVES:This study aims to analyze the accuracy and predictive ability of the Risk Instrument for Screening in the Community (RISC) scored by general practitioners (GPs) in a sample of primary care patients aged 80+ with perceived mental health concerns. METHOD:GPs ranked the perceived risk of the three adverse out...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2019.103974
更新日期：2020-01-01 00:00:00
abstract：:In a study of ten young and seven elderly healthy men we have performed an oral glucose tolerance test (75 g) and employed a euglycemic hyperinsulinemic (0.25 mUx kg/min) glucose clamp technique in order to determine insulin sensitivity. This latter experimental protocol consisted of 120 min of euglycemic clamp follow...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(90)90026-3
更新日期：1990-05-01 00:00:00
abstract：OBJECTIVE:To investigate the sex-difference in relation to the association between moderate-vigorous physical activity (MVPA) and sedentary time (ST) patterns with frailty. METHOD:Accelerometry from ≥50 year olds from the National Health and Nutrition Examination Survey (2003-04/2005-06 cycles) were included. Bouted a...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2019.103972
更新日期：2020-01-01 00:00:00
abstract：:Reliable aging markers are very rare, which are better than the chronological age or those symptoms which have such great individual variability that their scientific value is questionable. The effect of aging on immunological behavior of human (and animal) individuals is reasonably well established. In this communica...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(91)90030-t
更新日期：1991-03-01 00:00:00
abstract：:In a super-aged society, the need for prevention of locomotor dysfunction is growing, and evidence for feasible preventive measures is thus required. This study aimed to examine the relationship between these disorders and the prevalence rates for falling and physical function status. Participants included 1182 commun...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2013.05.005
更新日期：2013-11-01 00:00:00
abstract：:An example of multidimensional assessment procedure applied to the study of treatment effects in a type of pathological aging is presented in this paper. Data discussed here come from a clinical trial performed to evaluate the effects of an ergot derivate, dihydroergocristine, in CCVD memory deficits. The multidimensi...
journal_title：Archives of gerontology and geriatrics
pub_type： 临床试验,杂志文章
doi：10.1016/0167-4943(87)90041-0
更新日期：1987-04-01 00:00:00
abstract：:Cerebral hemodynamic responses due to normal aging may interfere with hormonal changes, drug therapy, diseases, life style, and other factors. Age-correlated alterations in cerebral vasculature and autoregulatory mechanisms are the subject of interest in many studies. Near-infrared spectroscopy (NIRS) is widely used f...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2004.03.007
更新日期：2004-11-01 00:00:00
abstract：:The cytotoxic activity of natural killer (NK) cells under both basal and interferon (IFN)-induced conditions, as well as the proliferative response of lymphocytes to ConA in old rats treated in vivo with AL-721 have been analyzed. The low levels of basal NK cell activity present in spleen of old rats were completely r...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/s0167-4943(05)80030-5
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVE:Evaluate the cumulative effects of cognitive impairment and frailty on functional decline, falls and hospitalization in older adults over a four-year period. METHOD:Four hundred five older adults (60-95 years; mean age: 70.62 ± 7.12 years), 57 % female. The frailty evaluation was performed using the clinical...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2019.104005
更新日期：2020-01-01 00:00:00
abstract：:The charts of patients who attended a geriatric day hospital (DH) over a 16-month period were reviewed retrospectively (n = 112). Home visits were conducted on consenting patients who made gains (either functional, psychosocial or medical) according to the chart review; they (and/or their caregivers) were questioned a...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2004.08.001
更新日期：2005-03-01 00:00:00
abstract：:The purpose of this paper is to describe the development and initial piloting of a Functional Status Assessment of Seniors in Emergency Department (FSAS-ED). The methodology of development of the tool included (1) specifying the underlying construct based on the conceptual framework of the International Classification...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2008.01.009
更新日期：2009-03-01 00:00:00
abstract：:Between January 1993 and July 1994, 141 consecutive patients were recruited, all above 50 years of age, affected by chronic liver diseases (CLD), in order to evaluate the prevalence of hepatitis C virus (HCV). The overall prevalence of HCV alone was 50.3% (71 out of 141 patients) which increased to 70.1% when consider...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(96)86955-X
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Systematic reviews on healthy ageing interventions have primarily focused on assessing their effectiveness, not the implementation processes underpinning them, and the factors influencing program effectiveness. This has created a knowledge gap about what are effective implementation approaches...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章,评审
doi：10.1016/j.archger.2020.104263
更新日期：2021-01-01 00:00:00
abstract：:The nutritional assessment of the elderly shows several interpretative difficulties due to the lack of standard parameters. Moreover chronic age-related diseases can interfere with the physiological nutritional status. Anthropometric (triceps skinfold, arm muscle area, total body muscle mass, fat mass and Body Mass In...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(94)00578-u
更新日期：1995-03-01 00:00:00
abstract：:With advancing age functional and morphological changes take place within the intestinal tract. The age-dependency of intestinal absorption has been studied using a D-xylose absorption test. The absorption rate (constant k12), the time of appearance of the relative maximum of the D-xylose concentrations in the blood s...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/0167-4943(84)90002-5
更新日期：1984-07-01 00:00:00
abstract：BACKGROUND:With the aging phenomenon, there is growing interest in developing effective strategies to counteract dynapenia, the age-related loss of muscle strength. The positive effect of progressive resistance training on muscle strength is well known, however, the effect of nutritional supplementation or its synergis...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.archger.2020.104098
更新日期：2020-01-01 00:00:00
abstract：:The aim was to determine the validity and usefulness of hand-held dynamometry for measuring muscle strength in independent community-dwelling older persons. Cross-sectional study was performed in 281 subjects aged over 65, mean age of 74.3 years. The strength of six muscle groups was measured in three consecutive atte...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2011.02.006
更新日期：2012-01-01 00:00:00
abstract：UNLABELLED:Knee pain is a common health problem in the elderly population, for which non-invasive treatments are recommended as a first line treatment in the management of knee pain. A randomized controlled trial was conducted to determine the effects of exercise with or without thermal therapy in community-dwelling el...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.archger.2013.06.008
更新日期：2013-11-01 00:00:00
abstract：AIM:We aimed to compare diagnostic differences for identification of sarcopenia using the original operational definition developed by the European Working Group on Sarcopenia in Older People (EWGSOP1) and the most recently revised EWGSOP2 definition in community dwelling older adults with type 2 diabetes mellitus (T2D...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2020.104081
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:To examine the association between WC and BMI on disability among older adults from LAC. METHODS:Cross-sectional, multicenter city study of 5786 subjects aged 65 years and older from the Health, Well-Being and Aging in Latin America and the Caribbean (SABE) study (1999-2000). Sociodemographic variables, smokin...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2012.04.006
更新日期：2012-09-01 00:00:00
abstract：:Achieving guideline-recommended blood pressure targets is difficult in older adults with hypertension. We completed a subgroup analysis of patients 65 years of age or older enrolled in PREVIEW, a prospective, multicenter, pharmacoepidemiological study of the determinants and outcomes of second-line antihypertensive tr...
journal_title：Archives of gerontology and geriatrics
pub_type： 杂志文章
doi：10.1016/j.archger.2009.07.009
更新日期：2010-07-01 00:00:00
