Abstract:
:Quantitative ultrasound (QUS) is used for prediction for risks of osteoporotic fractures at various skeletal sites, irrespective of weight-bearing or non-weight-bearing skeletons. In the current study, we investigated the correlation between calcaneal QUS measurements (BUA, VOS, and Soundness) and volumetric trabecular, cortical, and its integral bone mineral density (tBMD, cBMD, and iBMD) using peripheral quantitative computed tomography (pQCT) of the weight-bearing distal tibia and non-weight-bearing distal radius in 198 healthy Chinese women between 40 and 62 years of age. Results showed that BUA, VOS, and Soundness measured by calcaneal QUS were significantly correlated with tBMD, cBMD, and iBMD of both distal tibia and distal radius (r = 0.210-0.447; all P < 0.01). The correlation coefficients of all the individual parameters between calcaneus and distal tibia were correspondingly higher (r = 0.214-0.447; all P < 0.01) than that of distal radius (r = 0.210-0.368; all P < 0.01). QUS Soundness showed the highest correlation (r = 0.447; P < 0.01) with tBMD of distal tibia when comparing with all other parameters between these two measurement devices. Stronger "within-device" correlations (r = 0.640-0.764; all P < 0.01) were found in pQCT measurements between distal tibia and radius. In addition, the largest and significant age-related decline was found in tBMD of the distal radius measured by pQCT and Soundness of the QUS measurement in the postmenopausal group. In conclusion, heel QUS measurement demonstrated slightly better correlation with trabecular bone of the weight-bearing skeleton than that of the non-weight-bearing skeleton measured by pQCT.
journal_name
J Bone Miner Metabjournal_title
Journal of bone and mineral metabolismauthors
Hung VW,Qin L,Au SK,Choy WY,Leung KS,Leung PC,Cheng JCdoi
10.1007/s00774-004-0511-5subject
Has Abstractpub_date
2004-01-01 00:00:00pages
486-90issue
5eissn
0914-8779issn
1435-5604journal_volume
22pub_type
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journal_title:Journal of bone and mineral metabolism
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journal_title:Journal of bone and mineral metabolism
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journal_title:Journal of bone and mineral metabolism
pub_type: 杂志文章
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更新日期:2004-01-01 00:00:00
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