Abstract：
:The National Institute of Mental Health (NIMH) Treatment of Depression Collaborative Research Program (Elkin et al., Archives of General Psychiatry, 46, 971-982; 1989) reported treatment-by-severity interactions favouring pharmacotherapy for more depressed outpatients, on a minority of relevant comparisons. The present study reports secondary analyses from a similar, preexisting data set in which treatment-by-severity interactions are systematically investigated with depressed outpatients treated either with nondirective psychotherapy, behaviour therapy, pharmacotherapy, or relaxation/placebo. Despite multiple severity measures and variable severity cut scores, no treatment was differentially effective in improving more severely depressed patients. Also, there was little difference across symptom severity levels in the proportions of recovered patients between treatment groups. Finally, dynamic cluster analysis demonstrated that the proportion of pharmacotherapy nonresponders (20%) did not differ from the proportion of nonresponders in behaviour therapy or placebo groups. It is concluded that this failure to replicate the NIMH trial findings can not be attributed to treatment differences, populations or statistical power. The suggestion that pharmacotherapy be the treatment of choice for more severely depressed outpatients appears to be unjustified on the basis of available evidence.
journal_name
Behav Res Therjournal_title
Behaviour research and therapyauthors
McLean P,Taylor Sdoi
10.1016/0005-7967(92)90028-fsubject
Has Abstractpub_date
1992-09-01 00:00:00pages
443-51issue
5eissn
0005-7967issn
1873-622Xpii
0005-7967(92)90028-Fjournal_volume
30pub_type
临床试验,杂志文章,随机对照试验abstract：:This study examined the cross-sectional factorial invariance of anxiety sensitivity in an ethnically diverse sample of adolescents (n = 173; mean age 15.5 years) and young adults (n = 291; mean age 20.1 years). Research in adult and youth samples suggests that anxiety sensitivity is best understood as a hierarchical c...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2004.06.008
更新日期：2005-06-01 00:00:00
abstract：:There has been much recent controversy regarding whether or not the use of safety and other neutralizing behaviour interferes with exposure-based therapy. The aim of this study was to examine the role of safety behaviour in the treatment of specific phobia. Sixty-two snake-fearful participants were randomized to a 45-...
journal_title：Behaviour research and therapy
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brat.2008.05.011
更新日期：2008-10-01 00:00:00
abstract：:Unlike the multiple sleep latency test, pupillometry does not require sleep to test sleepiness, which may be an advantage in assessing insomniacs. Pupillometry was employed to study possible differences in daytime sleepiness between insomniacs and noninsomniacs. Thirty self-defined insomniacs and an equal number of no...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/0005-7967(94)90093-0
更新日期：1994-01-01 00:00:00
abstract：:Social phobics exhibit an attentional bias for threat in probe detection and probe discrimination paradigms. Attention training programs, in which probes always replace nonthreatening cues, reduce attentional bias for threat and self-reported social anxiety. However, researchers have seldom included behavioral measure...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2011.10.005
更新日期：2012-01-01 00:00:00
abstract：:Nightmares can be effectively treated with cognitive-behavioral therapies. Though it remains elusive which therapeutic elements are responsible for the beneficial effects on nightmare symptoms, imagery rescripting (IR) and imaginal exposure (IE) are commonly identified as active treatment components of nightmare thera...
journal_title：Behaviour research and therapy
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brat.2017.06.005
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND:Elevated levels of anxiety and panic are common in respiratory disease. To date the cognitive-behavioural model of panic has been utilised to help explain and manage panic in respiratory disease. This cross-sectional study investigated the relationship between illness perceptions and panic in chronic obstruc...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2008.10.004
更新日期：2009-01-01 00:00:00
abstract：:The current study investigated whether physical anxiety sensitivity (AS) is associated with selective attentional biases to affective stimuli in children. The dot-probe paradigm was used to examine the deployment of attention towards words pertaining to anxiety symptomatology, socially threatening words, and positive ...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2006.04.001
更新日期：2007-03-01 00:00:00
abstract：:The purpose of this paper is to consider the possible origins of an inflated sense of responsibility which occupies an important place in the cognitive theory of obsessive compulsive disorder (Rachman, S. (1993). Obsessions, responsibility, and guilt. Behaviour Research and Therapy, 31, 149-154. Salkovskis, P. M. (198...
journal_title：Behaviour research and therapy
pub_type： 杂志文章,评审
doi：10.1016/s0005-7967(99)00063-7
更新日期：1999-11-01 00:00:00
abstract：:We investigated the effects of awareness on selective attention for masked and unmasked verbal threat material using a computerised version of the emotional Stroop. Participants were assigned to the high trait anxious (HTA) and low trait anxious (LTA) groups on the basis of questionnaire scores, and state anxiety was ...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2009.11.003
更新日期：2010-03-01 00:00:00
abstract：:The present study investigated predictors of treatment outcome and dropout in two samples of PTSD-patients with mixed traumas treated using prolonged imaginal exposure. Possible predictors were analysed in both samples separately, in order to replicate in one sample findings found in the other. The only stable finding...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/s0005-7967(01)00024-9
更新日期：2002-04-01 00:00:00
abstract：:Previous research has shown that high socially anxious individuals lack the benign interpretation bias present in people without social anxiety. The tendency of high socially anxious people to generate more negative interpretations may lead to anticipated anxiety about future social situations. If so, developing a mor...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2007.01.007
更新日期：2007-07-01 00:00:00
abstract：:The role of avoidance behavior in perpetuating the experience of intrusive thoughts among burn survivors was investigated. The Impact of Events Scale (IES), which has subscales that measure the frequency of intrusive thoughts and avoidance behavior, was administered to burn survivors (n = 23) upon discharge and four m...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/0005-7967(96)00019-8
更新日期：1996-08-01 00:00:00
abstract：:The aim of the present study was to replicate Radomsky and Rachman's findings on memory bias in obsessive-compulsive disorder (OCD), using the same procedure but an increased sample size, more specific control groups, and a full analysis of contamination attribution data. Sixteen OCD-washers, 16 OCD-checkers, 16 socia...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/s0005-7967(03)00040-8
更新日期：2003-06-01 00:00:00
abstract：:The Body Project is a dissonance-based selective eating disorder prevention program with a broad evidence-base. The study sought to determine if previous findings regarding participant moderators replicate in an effectiveness trial under more real-world conditions. This study also had the novel aim of examining facili...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2014.08.004
更新日期：2014-10-01 00:00:00
abstract：:This study investigates two factors hypothesised as relevant to obsessional problems because of the way in which they influence decisions whether or not to act to prevent harm. These are (i) the way in which intrusive thoughts increase the internal awareness of harm, and confront the person with the possibility of tak...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/s0005-7967(99)00145-x
更新日期：2000-12-01 00:00:00
abstract：OBJECTIVE:Although there is compelling evidence that trauma-focused cognitive behavioral therapy (TF-CBT) is an effective treatment for traumatized youth, we know less about the mechanisms contributing to symptom reduction. To improve the understanding of change mechanisms in TF-CBT, this paper investigates the possibl...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2018.10.010
更新日期：2018-12-01 00:00:00
abstract：:Sexual assault risk reduction programs do not target alcohol use despite the widespread knowledge that alcohol use is a risk factor for being victimized. The current study assessed the effectiveness of a web-based combined sexual assault risk and alcohol use reduction program using a randomized control trial. A total ...
journal_title：Behaviour research and therapy
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brat.2015.08.007
更新日期：2015-11-01 00:00:00
abstract：:Limited research has indicated the effectiveness of the school-based Cognitive Behavioral Therapy (CBT) prevention program 'Op Volle Kracht (OVK)' and the computerized CBT program 'SPARX' in decreasing depressive symptoms. Therefore, a randomized controlled trial of the effectiveness of OVK and SPARX was conducted amo...
journal_title：Behaviour research and therapy
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brat.2016.03.005
更新日期：2016-05-01 00:00:00
abstract：:Interference effects on threat words in anxious subjects on the emotional Stroop task have generally been interpreted as evidence for mood-congruent attentional bias in anxiety states. However, several recent studies have yielded results that run contrary to this attentional bias explanation. The most important of the...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/0005-7967(94)90128-7
更新日期：1994-03-01 00:00:00
abstract：:In evidence-based mental health practice, decisions must often be made for which there is little or no empirical basis. A common example of this is when there are multiple empirically supported interventions for a person with a given diagnosis, where the aim is to recommend the treatment most likely to be effective fo...
journal_title：Behaviour research and therapy
pub_type： 历史文章,杂志文章
doi：10.1016/j.brat.2019.103506
更新日期：2019-12-01 00:00:00
abstract：:Ley (Behaviour Research and Therapy, 29, 301-304, 1991) provided a reinterpretation of experimental findings on the efficacy of breathing retraining plus cognitive restructuring in reducing the symptomatology of patients with panic disorder with agoraphobia which were presented in a 1989 article in this journal. On th...
journal_title：Behaviour research and therapy
pub_type： 评论,杂志文章
doi：10.1016/0005-7967(92)90010-e
更新日期：1992-11-01 00:00:00
abstract：:The present study explores driving skills in a group of 50 media-recruited driving-fearful and 50 control drivers, all of whom were women. Participants completed an on-road practical driving assessment with a professional driving instructor. Diagnostic as well as pre-post self-report and instructor driving assessments...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2006.07.007
更新日期：2007-04-01 00:00:00
abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2010.10.009
更新日期：2010-11-02 00:00:00
abstract：:Failures to retrieve specific memories have been related to general tendencies to commit errors in executive functioning tasks, raising the question of whether they are simply a reflection of randomly occurring lapses in cognitive control or whether their occurrence is in any way related to memory content. This study ...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2007.02.006
更新日期：2007-08-01 00:00:00
abstract：:Attentional bias modification (ABM) is a promising therapeutic tool aimed at changing patterns of attentional selectivity associated with heightened anxiety. A number of studies have successfully implemented ABM using the modified dot-probe task. However others have not achieved the attentional change required to achi...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2014.12.007
更新日期：2015-02-01 00:00:00
abstract：:Recent theoretical accounts point to disgust as an important factor in the development and persistence of sexual dysfunctions. This study tested if (i) contingent disgust experiences can render initially sexually arousing stimuli disgusting, and (ii) such acquired disgust responses could be best neutralized via a CS-o...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2020.103714
更新日期：2020-11-01 00:00:00
abstract：:An increasing body of evidence has linked pathological body-focused repetitive behaviors (BFRBs) to excessive sensory sensitivity and difficulty modulating sensory inputs. Likewise, neurobiological evidence points to deficits in feed-forward inhibition and sensory habituation in conditions with similar symptomatology....
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2019.103433
更新日期：2019-09-01 00:00:00
abstract：:We examined whether the effect of an extinction phase can be influenced retrospectively by information about the cause of the absence of the unconditioned stimulus (US) during that phase. Participants were subjected to a differential fear conditioning procedure, followed by an extinction procedure. Afterwards, half of...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2010.12.004
更新日期：2011-03-01 00:00:00
abstract：:Past research has largely focused on examining self-esteem as an independent as opposed to a dependent variable. At the same time, research suggests that during adolescence, self-esteem is subject to yearly, monthly, as well as daily change, and consequently, it is important to identify underlying vulnerability factor...
journal_title：Behaviour research and therapy
pub_type： 杂志文章
doi：10.1016/j.brat.2012.06.002
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND:The effectiveness of a combined methylphenidate/behavioural treatment (BT) versus methylphenidate-only for Chinese children with Attention-Deficit/Hyperactivity Disorder (ADHD) was tested in routine clinical practice in Hong Kong. METHODS:A randomized group comparison design was adopted with two treatment c...
journal_title：Behaviour research and therapy
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brat.2008.06.007
更新日期：2008-09-01 00:00:00
