Abstract：
:We examined the serum concentrations of leptin in a homogeneous group of 52 postmenopausal Mediterranean women, calculating body fat mass distribution by waist-to-hip circumference ratio (WHR) and other anthropometric measurements. Significant correlations were found between leptin and weight (r=0.59), Body Mass Index (BMI) (r=0.56), Conicity Index (CI) (r=0.49) and all circumferences measured: chest (r=0.55), waist (0.61) and hip (r=0.65), but not between leptin and WHR. Leptin levels does not seem to be influenced by fat mass distribution (android or gynoid type) while weight gain over life appears to be related with the hormone concentration when menopausal status is well established.
journal_name
J Physiol Biochemjournal_title
Journal of physiology and biochemistryauthors
Martínez-Carpio PA,Fiol C,Hurtado I,Arias C,Ruiz E,Orozco P,Corominas Adoi
10.1007/BF03179888subject
Has Abstractpub_date
2003-12-01 00:00:00pages
301-7issue
4eissn
1138-7548issn
1877-8755journal_volume
59pub_type
杂志文章abstract：:Adiponectin exerts vasodilatory effects. Irbesartan, an angiotensin receptor blocker, possesses partial peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist activity and increases circulating adiponectin. This study explored the effect of irbesartan alone and in combination with adiponectin on blood press...
journal_title：Journal of physiology and biochemistry
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doi：10.1007/s13105-016-0497-1
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abstract：:Human diploid fibroblasts (HDFs) proliferation in culture has been used as a model of aging at the cellular level. Growth arrest is one of the most important mechanisms responsible for replicative senescence. Recent researches have been focusing on the function of vitamin E in modulating cellular signaling and gene ex...
journal_title：Journal of physiology and biochemistry
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doi：10.1007/s13105-016-0524-2
更新日期：2017-02-01 00:00:00
abstract：:In response to stress, the hypothalamus releases cortiticotropin releasing hormone (CRH) that travels to the anterior pituitary, where it stimulates the release of adrenocorticotropic hormone (ACTH). ACTH travels to the adrenal cortex, where it stimulates the release of cortisol and other steroids that liberate energy...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章,评审
doi：10.1007/s13105-012-0227-2
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abstract：:Glitazones are peroxisome proliferator-activated receptor gamma (PPARγ) agonists widely used as antidiabetic drugs also known as thiazolidinediones. Most of them exert other effects such as anti-inflammatory actions via mechanisms supposed to be independent from PPARγ activation (e.g., decreased plasma monocyte chemoa...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-014-0379-3
更新日期：2015-09-01 00:00:00
abstract：:We and others have demonstrated a protective role for pacing postconditioning (PPC) against ischemia/reperfusion (I/R) injury in the heart; however, the underlying mechanisms behind these protective effects are not completely understood. In this study, we wanted to further characterize PPC-mediated cardiac protection,...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-016-0535-z
更新日期：2017-05-01 00:00:00
abstract：:S-resistin is a non-secretable resistin spliced variant, which is expressed mainly in the white adipose tissue from Wistar rats. Previous results confirmed that 3T3-L1 cells expressing s-resistin (3T3-L1-s-res) showed an inflammatory response and exhibited a decrease in glucose transport, both basal and insulin-stimul...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-015-0418-8
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abstract：:Oxidative stress has been shown to induce apoptosis in cancer cells. Therefore, one might suspect that antioxidants may inhibit reactive oxygen species (ROS) and prevent apoptosis of cancer cells. No study has been carried out so far to elucidate the effects of N-acetylcysteine (NAC) on bleomycin-induced apoptosis in ...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
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更新日期：2012-12-01 00:00:00
abstract：:Total level of O-acetyl-L-serine(thiol)lyase (OASTL) activity observed in Monoraphidium braunii fed-repleted cells decreases up to 40% after 24 h the carbon source was removed from the culture; however, no significant change in the activity is observed in N-starved cells. On the other hand, sulfur starvation induces O...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：
更新日期：1998-09-01 00:00:00
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journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-013-0250-y
更新日期：2013-12-01 00:00:00
abstract：:Transcriptional factors are easily susceptible to any stimuli, including exercise. Exercise can significantly influence PGC-1 α and AMPK-SIRT1 pathway, as it is involved in the regulation of energy metabolism and mitochondrial biogenesis. Exercise is a major energy deprivation process by which many of transcription fa...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章,评审
doi：10.1007/s13105-017-0576-y
更新日期：2017-11-01 00:00:00
abstract：:The study investigates the effect of weight-maintaining high-sucrose (HSD) and high-fat (HFD) diets on plasma glucose and insulin concentrations in lean and obese women, and verifies the correlation between insulin profile and body composition. Lean (G1 group, n=6, BMI= 21.4 (20.2-22.8) kg/m2) and overweight/obese (G2...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/BF03168238
更新日期：2008-06-01 00:00:00
abstract：:Adipose tissue has long been considered to be involved in tumor progression. However, the adipocyte-secreted molecular determinants that regulate hepatocellular cancer progression have not been defined yet. In this study, the expression pattern of exosome miRNAs in hepatocellular carcinoma (HCC) patients with high bod...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-019-00692-6
更新日期：2019-08-01 00:00:00
abstract：:In traditional herbal medicine, Rock Tea (Jasonia glutinosa) is known for its prophylactic and therapeutic value in various disorders including arterial hypertension. However, the mechanism by which Rock Tea exerts blood pressure-lowering actions has not been elucidated yet. Our aim was to demonstrate vasorelaxing eff...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-015-0442-8
更新日期：2015-12-01 00:00:00
abstract：:In pregnancy there occurs maternal tolerance to the foetus. Several mechanisms have been proposed to explain this phenomenon. The main immune population in the decidua are macrophages and natural killer cells, but with some "special" suppressor characteristics. There is also a predominant TH2 response. The non classic...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章,评审
doi：10.1007/BF03167033
更新日期：2004-09-01 00:00:00
abstract：:Although the human homologue of SND p102, p100 coactivator, was initially described as a nuclear protein, the p100 coactivator protein family members have non-nuclear localization in mammalian cells with active lipid handling, storage, and secretion. However, their role in lipid homeostasis remains unresolved. Here, w...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-010-0011-0
更新日期：2010-03-01 00:00:00
abstract：:Human leukocyte antigen (HLA)-G is an immunomodulatory molecule discovered for the first time in the maternal-fetal interface. In cancer context, where high number of natural killer (NK) cells is described, the presence of HLA-G in its soluble form is thought to be essential for NK cells signaling. To evaluate intrace...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-010-0005-y
更新日期：2010-03-01 00:00:00
abstract：:The present study was designed to evaluate the cardioprotective effect of Tunisian flaxseed oil (Linum usitatissimum) against isoproterenol-induced myocardial infarction in rats by studying hypertensive and cardiac damage markers especially electrocardiographic changes and troponin T serum level. In vitro, the extract...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-015-0411-2
更新日期：2015-06-01 00:00:00
abstract：:Decline in oxygen availability experienced under hypobaric hypoxia (HH) mediates imbalance in lung fluid clearance and is a causative agent of acute lung injury. Here, we investigate the pathological events behind acute HH mediated lung injury and assess the therapeutic efficacy of nanocurcumin in its amelioration. We...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-016-0515-3
更新日期：2016-12-01 00:00:00
abstract：:The prevalence of non-alcoholic fatty pancreas disease (NAFPD) is increasing in parallel with obesity rates. Stress-related alterations in endoplasmic reticulum (ER), such as the unfolded protein response (UPR), are associated with obesity. The aim of this study was to investigate ER imbalance in the pancreas of a mic...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-016-0476-6
更新日期：2016-06-01 00:00:00
abstract：:O-Acetylserine(thiol)lyase (OASTL) enzyme catalyzes the cysteine biosynthesis in photosynthetic organisms. In mature Arabidopsis thaliana the highest activity level is observed in non-photosynthetic tissues like roots, that also show significant amount of protein detected by Western blot analysis. By means of specific...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：
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abstract：:Thrombospondin 1 (TSP-1), an antiangiogenic factor and transforming growth factor (TGF)-β activity regulator, has been recently recognized as an adipokine that correlates with obesity, inflammation and insulin resistance processes. In the present study, epididymal adipocytes of rats that were fed a chow or a high-fat ...
journal_title：Journal of physiology and biochemistry
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abstract：:Diabetes is a risk factor for cardiovascular disease that has a multifactorial etiology, with oxidative stress as an important component. Our previous observation of a significant diabetes-related increase in rat cardiac catalase (CAT) activity suggested that CAT could play a major role in delaying the development of ...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-014-0363-y
更新日期：2014-12-01 00:00:00
abstract：:Serotonin (5-HT) is one of the regulators of feeding in humans. Drugs acting on the serotoninergic system are used to treat bulimia nervosa and to enhance the effect of hypocaloric diets in overweight subjects. They act rapidly to normalise feeding when used to treat eating-related problems. To explore the role of the...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-012-0188-5
更新日期：2013-03-01 00:00:00
abstract：:While carnitine overload appears to have therapeutic effects in pathological situations such as heart recovery after ischemia, its benefits as dietary supplementation for aerobic exercise have been questioned. We studied the effect of carnitine supplementation on the response of perfused rat heart to ischemia and repe...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/BF03168229
更新日期：2008-03-01 00:00:00
abstract：:Gut bacteria play an important role in several metabolic processes and human diseases, such as obesity and accompanying co-morbidities, such as fatty liver disease, insulin resistance/diabetes, and cardiovascular events. Among other factors, dietary patterns, probiotics, prebiotics, synbiotics, antibiotics, and non-di...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章,评审
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更新日期：2018-02-01 00:00:00
abstract：:Activation of 5' adenosine monophosphate-activated protein kinase (AMPK) with aminoimidazole carboxamide ribonucleotide (AICAR) increases skeletal muscle glucose uptake and fatty acid oxidation. The purpose of these experiments was to utilize AICAR to enhance palmitate consumption by mitochondria in cultured skeletal ...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-013-0269-0
更新日期：2013-12-01 00:00:00
abstract：:The protective effects of downregulated miR-199a-5p on ischemic and hypoxic cardiomyocytes were well recognized, but the underlying mechanism of inhibited miR-199a-5p is not yet clear. The present study explored the relationship between enhanced signal transducer and activator of transcription 3 (STAT3) signaling and ...
journal_title：Journal of physiology and biochemistry
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abstract：:This study was designed to investigate effects of raloxifene (RLX) and estradiol on bone formation and resorption in intact and ovariectomized (ovx) rat models. In the intact model, a total of 24 adult female rats were divided into three groups: Controls subcutaneously received saline alone. RLX (2 mg/kg) and estradio...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-010-0008-8
更新日期：2010-03-01 00:00:00
abstract：:Lipoic acid (LA) is an antioxidant with therapeutic properties on several diseases like diabetes and obesity. Apelin is a novel adipokine with potential beneficial actions on glucose metabolism and insulin resistance. The aim of this study was to examine in 3T3-L1 adipocytes the effects of LA on apelin gene expression...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-011-0087-1
更新日期：2011-09-01 00:00:00
abstract：:Our previous findings demonstrated that hypothermia enhances the reduction potential in the liver and helps to maintain the plasmatic antioxidant pool. Here, we aimed to elucidate if hypothermia protects against hypoxia-induced oxidative stress damage in rat liver. Several hepatic markers of oxidative stress were comp...
journal_title：Journal of physiology and biochemistry
pub_type： 杂志文章
doi：10.1007/s13105-016-0500-x
更新日期：2016-12-01 00:00:00
