Abstract:
PURPOSE:To study the effect of disposable extended-wear soft contact lenses on the corneal epithelium. METHODS:Thirteen healthy patients (1 male, 12 females; average age, 26.3 +/- 7.6 years) with or without histories of previous contact lens use were recruited for this study. Specular microscopic pictures of the corneal epithelium and endothelium were taken with the help of a specular contact lens, before and after 3 months of contact lens use. The pictures were analyzed by means of a computer-assisted morphometric analysis system. RESULTS:The mean cell area and coefficient of variation (CV) of the mean cell area of the corneal epithelium before contact lens use were 639.4 +/- 84.0 microns 2 and 29.1 +/- 13.2, respectively. After lens wear, the mean cell area increased to 819.7 +/- 99.2 microns 2 (P less than 0.01), whereas the CV decreased to 20.0 +/- 6.1 (P less than 0.05). The corresponding values for the endothelium were 300.8 +/- 22.5 microns 2 and 36.4 +/- 7.3 before contact lens use, and remained at 322.3 +/- 27.8 microns 2 and 32.8 +/- 3.7 after contact lens use, respectively (P greater than 0.05). CONCLUSIONS:Based on the 3-month results, disposable extended-wear soft contact lenses caused similar enlargement of the mean cell area of the superficial corneal epithelium, as has been reported previously. It would appear that disposable lenses may cause the same metabolic and physiologic changes in the corneal epithelium as do conventional extended-wear soft contact lenses.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Tsubota K,Yamada Mdoi
10.1016/s0161-6420(92)31824-xsubject
Has Abstractpub_date
1992-08-01 00:00:00pages
1193-6issue
8eissn
0161-6420issn
1549-4713pii
S0161-6420(92)31824-Xjournal_volume
99pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract:OBJECTIVE:To develop a clinical classification system for age-related macular degeneration (AMD). DESIGN:Evidence-based investigation, using a modified Delphi process. PARTICIPANTS:Twenty-six AMD experts, 1 neuro-ophthalmologist, 2 committee chairmen, and 1 methodologist. METHODS:Each committee member completed an o...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.10.036
更新日期:2013-04-01 00:00:00
abstract::An ultrasound diagnostic coding system was developed that permitted entry of diagnoses into a programmable calculator, thus permitting rapid information retrieval of patients with a specific diagnosis or diagnoses as well as the number of patients with a specific diagnosis. Cataract, vitreous opacity, trauma, choroida...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(78)35564-0
更新日期:1978-11-01 00:00:00
abstract:OBJECTIVE:To report the incidence of macular hole reopening after initial successful surgery. DESIGN:A noncomparative retrospective case series. PARTICIPANTS:From a series of 137 consecutive cases of idiopathic macular holes operated on between August 1993 and May 1996, the authors analyzed the charts of 116 cases of...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(99)00182-7
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVE:To determine whether ocular cicatricial pemphigoid (OCP) may represent a distinct immunopathologic disease when it is pure ocular cicatricial pemphigoid (POCP) (e.g., only confined to the conjunctiva) or when it is associated with skin or extraocular mucous membrane lesions or both (OCP+). DESIGN:Prospective...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(99)90076-3
更新日期:1999-02-01 00:00:00
abstract:OBJECTIVE:To identify risk factors associated with failure of anatomic reattachment in primary rhegmatogenous retinal detachment repair. DESIGN:Nonrandomized, multicenter, collaborative study. PARTICIPANTS:Primary procedures for 7678 rhegmatogenous retinal detachments reported by 176 surgeons from 48 countries. METH...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2014.03.012
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:To evaluate the clinical features and management of diffuse infiltrating retinoblastoma. DESIGN:Retrospective case series. PARTICIPANTS:Thirty-four eyes in 32 patients. METHODS:The patients' records were reviewed for patient and tumor features, ocular management, histopathologic findings, and patient surviva...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2008.07.003
更新日期:2008-12-01 00:00:00
abstract:PURPOSE:To report a patient with a cystadenocarcinoma of the lacrimal gland, a tumor not previously described in the ophthalmic literature. Salivary gland cystadenocarcinomas constitute a distinct group of epithelial malignancies characterized by an invasive, predominantly cystic pattern of growth that have an indolent...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(03)00490-1
更新日期:2003-10-01 00:00:00
abstract::Dynamic ultrasonic imaging adds a time dimension to the clinical diagnosis of ocular pathology. A recent development in this area of ophthalmic sonography has been the introduction of an electronically scanned, multiple transducer system that provides improved real-time imaging of ocular tissue motion. This paper disc...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(83)34564-4
更新日期:1983-03-01 00:00:00
abstract::An elderly, Spanish-speaking patient, who was a poor historian, presented with a hemorrhagic corneal condition that was mistakenly diagnosed as a spontaneous expulsive choroidal hemorrhage leading to enucleation of the globe. The enucleation specimen revealed pathologically a diffuse hemorrhagic pannus without corneal...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(81)34964-1
更新日期:1981-07-01 00:00:00
abstract:PURPOSE:Droperidol and the new serotonin-3 antagonists are effective drugs for the prophylaxis of postoperative nausea and vomiting (PONV). The aim of this trial was to evaluate whether dolasetron could be a substitute for droperidol, because the Food and Drug Administration has required a Black Box warning on the drop...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ophtha.2004.01.031
更新日期:2004-08-01 00:00:00
abstract::A 60-year-old white woman developed lesions of the conjunctiva and skin consistent with iododerma. Excision and examination of one of the skin lesions and the conjunctival lesion disclosed pseudoepitheliomatous hyperplasia associated with acute and chronic inflammation. The remaining lesions disappeared with cessation...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(81)34870-2
更新日期:1981-12-01 00:00:00
abstract:PURPOSE:To describe 2 adult patients who presented with papilledema after band atrophy (i.e., twin and triple peaks papilledema). DESIGN:Retrospective small case series. PARTICIPANTS:Two outpatients. METHODS:Observations made on 2 patients whose cases were reviewed in the neuro-ophthalmology clinic. RESULTS:The fir...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2005.01.047
更新日期:2005-07-01 00:00:00
abstract:PURPOSE:Intraoperative floppy iris syndrome (IFIS) caused by systemic alpha-blockers has been associated with an increased risk of cataract surgical complications when the surgeon was unaware of the medication history and did not anticipate its occurrence. This study was undertaken to evaluate the surgical outcomes and...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2007.01.011
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:To study the nature of retinal inflammatory response in rd10 mice, an animal model of retinitis pigmentosa (RP), and to investigate the effect of an antioxidant on retinal inflammation and photoreceptor apoptosis. DESIGN:Experimental study. PARTICIPANTS AND CONTROLS:This study included 42 untreated rd10 mice,...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.07.008
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:To analyze the temporal correlations of vascular endothelial growth factor (VEGF) suppression, morphologic recurrence of choroidal neovascularization (CNV), and visual acuity loss in eyes with exudative age-related macular degeneration (AMD) treated with ranibizumab. DESIGN:Nonrandomized, prospective, clini...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.07.041
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:There are many alternatives available to the vitreoretinal surgeon in the management of posteriorly dislocated intraocular lenses (IOL). The lens may be repositioned in the ciliary sulcus if there is adequate capsular support, but if this support is absent, it must either be sutured in place (to the sclera or...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(98)96001-8
更新日期:1998-06-01 00:00:00
abstract:PURPOSE:To report quantitative changes in the anterior segment configuration after clear corneal incision phacoemulsification and foldable intraocular lens (IOL) implantation by means of ultrasound biomicroscopy (UBM). DESIGN:Prospective, nonrandomized, comparative (self-controlled) trial. PARTICIPANTS:Twenty-one eye...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/S0161-6420(03)00623-7
更新日期:2003-09-01 00:00:00
abstract::Unilateral visual loss following periocular corticosteroid injection is a reported complication of injections of tonsillar, nasal, scalp, and retrobulbar sites. This is the first reported case, to our knowledge, of intralesional corticosteroid injection of a chalazion producing ipsilateral microembolization and infarc...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(86)33728-x
更新日期:1986-03-01 00:00:00
abstract::This report details the presentation, workup, and treatment of the largest lacrimal duct cyst ever reported in the ophthalmic literature. Included in this report is the first computed tomographic (CT) image of this unusual lesion. Typical and atypical clinical features of this lacrimal sac cyst are emphasized. ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(87)33391-3
更新日期:1987-06-01 00:00:00
abstract:PURPOSE:To study the 3-year effect of oral nilvadipine, a calcium antagonist, on visual field performance and ocular circulation in open-angle glaucoma (OAG) with low-normal intraocular pressure (IOP). DESIGN:A randomized, placebo-controlled, double-masked, single-center trial. PARTICIPANTS:Patients with OAG who were...
journal_title:Ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ophtha.2008.05.015
更新日期:2008-11-01 00:00:00
abstract::Thirty-three type l diabetics who used continuous subcutaneous infusion of insulin (CSll) and 24 diabetics on conventional treatment (maximum of two injections per day) were studied prospectively with ophthalmologic examinations, fundus photography, fluorescein angiography, and glycosylated hemoglobin (HbA1) determina...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(85)33903-9
更新日期:1985-08-01 00:00:00
abstract:PURPOSE:Several retrospective studies have demonstrated the safety and efficacy of sub-Tenon's anesthesia in ocular surgery. This is the first prospective randomized study comparing sub-Tenon's versus retrobulbar anesthesia for glaucoma surgery. METHODS:Thirty-nine patients undergoing both inpatient and day surgery tr...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0161-6420(93)31440-5
更新日期:1993-10-01 00:00:00
abstract::Forty patients with acquired immunodeficiency syndrome (AIDS) were examined for ocular abnormalities. Twenty of these patients died and the eyes were obtained for culture and histopathologic examination. These patients have multiple opportunistic infections and neoplasms as the result of a severe depression of cellula...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(84)34201-4
更新日期:1984-09-01 00:00:00
abstract:BACKGROUND:The granular cell tumor (GCT) is a common, usually benign, neoplasm of uncertain histogenesis that may affect any organ in the body. It occurs rarely in ophthalmic sites, where orbital location is most frequent. The purpose of this report is to describe a unique case of an epibulbar, subconjunctival GCT in a...
journal_title:Ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/s0161-6420(97)30117-1
更新日期:1997-09-01 00:00:00
abstract:PURPOSE:To report the results of the first 2 years of experience with an American Academy of Ophthalmology (AAO) cataract surgery registry; to compare patient characteristics, operative procedures, and patient outcomes observed in the registry to those observed in the Cataract PORT study; and to discuss the current sho...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(99)00184-0
更新日期:2000-04-01 00:00:00
abstract:PURPOSE:To evaluate structural changes in the cornea and anterior chamber (AC) after LASIK for myopia. DESIGN:Retrospective nonrandomized study. PARTICIPANTS:One hundred sixty-one eyes of 83 patients (mean age, 34.5+/-8.3 years) who underwent uneventful LASIK for myopia and myopic astigmatism. The preoperative refrac...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2006.09.014
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:To describe the results from a statewide preschool vision screening program using the MTI PhotoScreener (Medical Technology and Innovations, Inc., Cedar Falls, IA). DESIGN:Cross-sectional study. PARTICIPANTS:A total of 15,059 children aged 6 to 47 months enrolled in childcare and preschool settings throughout...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(00)00298-0
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:To report the outcomes of ipsilateral rotational autokeratoplasty (RAK) for nonprogressive paracentral corneal opacities in children <16 years of age. DESIGN:Retrospective, consecutive, interventional case series. PARTICIPANTS:Thirty-three eyes of 33 children aged <16 years undergoing RAK for nonprogressive...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.06.045
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:Associations between glaucoma and survival have not been studied extensively, in part, because of the relatively low prevalence of this condition. This study examines associations between self-reported glaucoma and mortality in a nationally representative sample of U.S. adults. DESIGN:Annual cross-sectional ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(03)00408-1
更新日期:2003-08-01 00:00:00
abstract:PURPOSE:Indocyanine green (ICG) dye is known to remain selectively in and around choroidal neovascularization (CNV) associated with age-related macular degeneration, and is thought to be cleared from the overlying retinal circulation without leakage. This is the basis of ICG dye-enhanced laser photocoagulation. The aut...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(94)31323-6
更新日期:1994-03-01 00:00:00