Abstract:
:Chronic pain syndromes are associated with alterations in sleep continuity and sleep architecture. One perspective of this relationship, which has not received much attention to date, is that disturbances of sleep affect pain. To fathom this direction of cause, experimental human and animal studies on the effects of sleep deprivation on pain processing were reviewed. According to the majority of the studies, sleep deprivation produces hyperalgesic changes. Furthermore, sleep deprivation can counteract analgesic effects of pharmacological treatments involving opioidergic and serotoninergic mechanisms of action. The heterogeneity of the human data and the exclusive interest in rapid eye movement sleep deprivation in animals so far do not allow us to draw firm conclusions as to whether the hyperalgesic effects are due to the deprivation of specific sleep stages or whether they result from a generalized disruption of sleep continuity. The significance of opioidergic and serotoninergic processes as mediating mechanisms of the hyperalgesic changes produced by sleep deprivation are discussed.
journal_name
Pain Res Managjournal_title
Pain research & managementauthors
Kundermann B,Krieg JC,Schreiber W,Lautenbacher Sdoi
10.1155/2004/949187subject
Has Abstractpub_date
2004-04-01 00:00:00pages
25-32issue
1eissn
1203-6765issn
1918-1523journal_volume
9pub_type
杂志文章,评审abstract::Staff shortages, deficient knowledge, inappropriate attitudes, demanding workloads, analgesic shortages, and low prioritization of pain management have been identified in earlier studies as the nursing-related barriers to optimal children's pain management. These studies have mainly been undertaken in developed countr...
journal_title:Pain research & management
pub_type: 杂志文章
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journal_title:Pain research & management
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journal_title:Pain research & management
pub_type: 杂志文章
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journal_title:Pain research & management
pub_type: 杂志文章
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journal_title:Pain research & management
pub_type: 临床试验,杂志文章
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journal_title:Pain research & management
pub_type: 杂志文章
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journal_title:Pain research & management
pub_type: 杂志文章
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journal_title:Pain research & management
pub_type: 杂志文章
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journal_title:Pain research & management
pub_type: 杂志文章,meta分析
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journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
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更新日期:2020-05-06 00:00:00
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journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
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journal_title:Pain research & management
pub_type: 杂志文章
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journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2011/825636
更新日期:2011-01-01 00:00:00
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journal_title:Pain research & management
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更新日期:2019-01-27 00:00:00
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journal_title:Pain research & management
pub_type: 历史文章,杂志文章
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journal_title:Pain research & management
pub_type: 杂志文章
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更新日期:2012-03-01 00:00:00
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journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
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更新日期:2014-01-01 00:00:00
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journal_title:Pain research & management
pub_type: 杂志文章,评审
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更新日期:2005-10-01 00:00:00
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journal_title:Pain research & management
pub_type: 杂志文章
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journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Pain research & management
pub_type: 杂志文章
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更新日期:2011-09-01 00:00:00
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journal_title:Pain research & management
pub_type: 杂志文章,评审
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更新日期:2010-09-01 00:00:00
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journal_title:Pain research & management
pub_type: 杂志文章
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更新日期:2018-04-19 00:00:00
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journal_title:Pain research & management
pub_type: 杂志文章
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更新日期:2015-11-01 00:00:00
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