Abstract:
:Objectives. The aim of this study was to determine the effectiveness of preoperative administration of single-dose of paracetamol-codeine, in the relieving of acute postoperative pain after the surgical removal of an impacted mandibular third molar. Materials and Methods. The study cohort consisted of 32 Caucasian outpatients, giving a total of 64 bilateral symmetrical impacted mandibles. Patients were randomized in two experimental groups to receive a preoperative oral dose of paracetamol-codeine (analgesic group) or a placebo (placebo group) at the first and second surgeries. Study participants were asked to record pain intensity scores during the operation and the next 2 days, the time of the first request for rescue analgesic, and the total number of postoperative-supplement paracetamol-codeine tablets. Results. The pain intensity score on the first day was significantly lower in the analgesic group than in the placebo group (p < 0.001). The time to using rescue therapy was significantly longer in the analgesic group than in the placebo group (p = 0.004). The number of paracetamol-codeine tablets used postoperatively did not differ between the analgesic and placebo groups (p = 0.104). Conclusions. Preoperative paracetamol-codeine is effective in providing immediate postoperative pain control after third molar surgery and in delaying the initial onset of pain. This trial is registered with ClinicalTrials.gov Identifier (Registration Number): NCT03049878.
journal_name
Pain Res Managjournal_title
Pain research & managementauthors
Cristalli MP,La Monaca G,De Angelis C,Pranno N,Annibali Sdoi
10.1155/2017/9246352subject
Has Abstractpub_date
2017-01-01 00:00:00pages
9246352eissn
1203-6765issn
1918-1523journal_volume
2017pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:The present randomized, double-blinded, crossover study compared the efficacy and safety of a seven-day buprenorphine transdermal system (BTDS) and placebo in patients with low back pain of moderate or greater severity for at least six weeks. METHODS:Prestudy analgesics were discontinued the evening before r...
journal_title:Pain research & management
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1155/2010/216725
更新日期:2010-05-01 00:00:00
abstract:Objectives:To examine the interrater and intrarater reliability and construct validity of the Pain Behaviour Scale during standard physical performance tests in people with chronic low back pain and to confirm the test-retest reliability of the physical performance tests in this population. The Pain Behaviour Scale (Pa...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2019/2508019
更新日期:2019-02-03 00:00:00
abstract:BACKGROUND:Diminished executive function and attentional control has been reported in chronic pain patients. However, the precise pattern of impairment in these aspects of cognition in chronic pain remains unclear. Moreover, a decline in psychomotor speed could potentially influence executive and attentional control pe...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2012/962786
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To investigate the emotional and neurobehavioural status of patients suffering from chronic pain. METHODS:Fifteen male patients with chronic lower back pain and 15 healthy control subjects were studied for approximately six months. Pain was measured using a visual analogue scale. The WHO Neurobehavioral Core...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2011/825636
更新日期:2011-01-01 00:00:00
abstract:Objective:To assess the validity of an exposure score obtained from the Xm2 tool for all pharmacological and nonpharmacological strategies used by individuals to manage chronic pain. Methods:Using data from individuals with chronic pain, eXposure multimodal (Xm2) scores were calculated by assigning one point for every...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2018/2530286
更新日期:2018-12-12 00:00:00
abstract::Background. Dexamethasone is sometimes used as a coanalgesic because of its anti-inflammatory properties. Objective. To evaluate opioid use, postoperative pain intensity, and side effects after a single dose of dexamethasone in patients undergoing arthroscopic knee surgery. Methods. In this randomized controlled study...
journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
doi:10.1155/2016/4216469
更新日期:2016-01-01 00:00:00
abstract:Background:Despite the large body of research on sex differences in pain, there is a lack of knowledge about the influence of gender in the patient-provider encounter. The purpose of this study was to review literature on gendered norms about men and women with pain and gender bias in the treatment of pain. The second ...
journal_title:Pain research & management
pub_type: 杂志文章,评审
doi:10.1155/2018/6358624
更新日期:2018-02-25 00:00:00
abstract::Background. Oral health-related quality of life (OHRQoL) is impacted by periodontal disease and orofacial pain. There is a limited research examining the impact of avoidance of care or physiological arousal related to the fear of pain response on periodontal-related OHRQoL. Methods. Data are from the Center for Oral H...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2017/5491923
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Increasing attention is being devoted to cognitive-behavioural measures to improve interventions for chronic pain. OBJECTIVE:To develop an Italian version of the Coping Strategies Questionnaire - Revised (CSQ-R), and to validate it in a study involving 345 Italian subjects with chronic pain. METHODS:The qu...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2014/956828
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Pediatric chronic pain is a common problem with significant economic implications and devastating consequences on quality of life. The present report describes a case involving a 15-year-old girl with severe and debilitating chronic pain. RESULTS:Before her referral to a pain rehabilitation program, the pat...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2014/745458
更新日期:2014-07-01 00:00:00
abstract::Despite many recent advances in the past 40 years in the understanding of pain mechanisms, and in pain diagnosis and management, considerable gaps in knowledge remain, with chronic pain present in epidemic proportions in most countries. It is often unrelieved and is associated with significant socioeconomic burdens. S...
journal_title:Pain research & management
pub_type: 杂志文章,评审
doi:10.1155/2011/513423
更新日期:2011-11-01 00:00:00
abstract:Background:Chronic low back pain (CLBP) arising from degenerative disc disease continues to be a challenging clinical and diagnostic problem whether treated with nonsurgical, pain intervention, or motion-preserving stabilization and arthrodesis. Methods:Fourteen patients with CLBP, greater than 6 months, unresponsive ...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2018/6857983
更新日期:2018-08-14 00:00:00
abstract:BACKGROUND:Pregabalin (PGB) is a novel antiepileptic drug and is also used as a first-line medication for the treatment of neuropathic pain. However, the mechanisms of its analgesic effects remain largely unknown. OBJECTIVES:To elucidate the mechanisms underlying the antiallodynic action of PGB in rats with neuropathi...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2014/623830
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:We recently introduced the efficacy safety score (ESS) as a new "call-out algorithm" for management of postoperative pain and side effects. In this study, we report the influence of ESS recorded hourly during the first 8 hours after surgery on the mobility degree, postoperative nonsurgical complications, and...
journal_title:Pain research & management
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1155/2017/9431984
更新日期:2017-01-01 00:00:00
abstract::Neuropathic pain (NeP), generated by disorders of the peripheral and central nervous system, can be particularly severe and disabling. Prevalence estimates indicate that 2% to 3% of the population in the developed world suffer from NeP, which suggests that up to one million Canadians have this disabling condition. Evi...
journal_title:Pain research & management
pub_type: 共识发展会议,杂志文章,实务指引
doi:10.1155/2007/730785
更新日期:2007-04-01 00:00:00
abstract::Pain is one of the commonest reasons why children visit the hospital. Inadequately treated pain in children can negatively affect their physical, psychological, and social well-being; it also places financial burden on families of affected children and healthcare systems in general. Considering the eventual suffering ...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2020/7283473
更新日期:2020-02-13 00:00:00
abstract:BACKGROUND:Leptin, an adipocyte-produced cytokine, interacts with various hormones, including those of the hypothalamic-pituitary-adrenal axis. Fibromyalgia is a syndrome characterized by widespread pain accompanied by tenderness. The pathogenesis involves a disturbance in pain processing and transmission by the centra...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2012/350654
更新日期:2012-03-01 00:00:00
abstract::The psychological predictors of pain and disability were examined in a sample of people who sustained whiplash injuries during rear-end motor vehicle accidents. Sixty-five patients referred to a specialty pain clinic with a diagnosis of whiplash injury completed measures of depression, anxiety, catastrophizing, pain a...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2002/176378
更新日期:2002-07-01 00:00:00
abstract:Purpose:The purpose of this study was to investigate the prevalence of sleep disturbance and its clinical implication in patients with ASD. Methods:A total of 44 patients with ASD and 137 patients with lumbar spinal stenosis (LSS) were enrolled in the study. Forty four patients were selected from the LSS group after p...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2020/6294151
更新日期:2020-04-13 00:00:00
abstract:BACKGROUND:Dynamic mechanical allodynia is traditionally induced by manual brushing of the skin. Brushing force and speed have been shown to influence the intensity of brush-evoked pain. There are still limited data available with respect to the optimal stroke number, length, force, angle and speed. Therefore, an autom...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2013/142582
更新日期:2013-01-01 00:00:00
abstract::Chronic back pain is often a result of coexisting pathologies; secondary causes of pain can become more apparent sources of pain once the primary pathology has been addressed. The objective of our study was to determine if there is an increase in diagnosis of Sacroiliac joint pain following a Lumbar Rhizotomy. A list ...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2017/4830142
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Exercising for ≥ 150 min/week is a recommended strategy for self-managing arthritis. However, exercise nonadherence is a problem. Arthritis pain anxiety may interfere with regular exercise. According to the fear-avoidance model, individuals may confront their pain anxiety by using adaptive self-regulatory re...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2015/853961
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Reports indicate that characteristics of older adults with chronic pain may be different than those of younger persons. OBJECTIVE:To study the pain characteristics of older patients presenting to a tertiary pain clinic for the first time. METHODS:Age, sex and relative contributions of biomedical versus psy...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2008/541963
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To provide an overview of the history and pharmacology of cannabis in relation to current scientific knowledge concerning actual and potential therapeutic uses of cannabis preparations and pure cannabinoids. METHODS:The literature on therapeutic uses of cannabis and cannabinoids was assessed with respect to ...
journal_title:Pain research & management
pub_type: 历史文章,杂志文章
doi:10.1155/2001/469629
更新日期:2001-07-01 00:00:00
abstract:Purpose:We aimed to present our experience in anchoring technique and evaluate the efficacy and safety of unilateral percutaneous vertebroplasty in patients with neurologically intact Kümmell's disease. Methods:From January 2014 to December 2017, 29 patients (17 males and 12 females) with neurologically intact Kümmell...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2020/4145096
更新日期:2020-05-24 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Chronic pain affects between 30% and 50% of the world population. Our objective was to estimate the prevalence of chronic pain in Brazil, describe and compare differences between pain types and characteristics, and identify the types of therapies adopted and the impact of pain on daily life. ...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2017/4643830
更新日期:2017-01-01 00:00:00
abstract:Objectives:The easily performed "cough-trick" (CT) reduces pain during venipuncture (VP), although the underlying mechanism remains unclear. The aim was to investigate the pain-reducing effect of CT during VP in comparison with two distraction methods, as well as under the influence of naloxone. Methods:54 healthy mal...
journal_title:Pain research & management
pub_type: 临床试验,杂志文章
doi:10.1155/2019/9459103
更新日期:2019-12-12 00:00:00
abstract:Background:Occlusal appliances are still widely used instruments in the management of orofacial pain in dentistry, yet alone or as a part of multimodal therapy. However, some of those modalities have been lacking thorough randomized assessment, and there is a conflicting evidence available. It is hypothesized that pain...
journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
doi:10.1155/2019/7954291
更新日期:2019-03-11 00:00:00
abstract::Radiotherapy is commonly used to treat cancer patients. Besides the curable effect, radiotherapy also could relieve the pain of cancer patients. However, cancer pain is gradually alleviated about two weeks after radiotherapy. In addition, cancer patients who receive radiotherapy may also suffer from pain flare or radi...
journal_title:Pain research & management
pub_type: 杂志文章,评审
doi:10.1155/2020/7565962
更新日期:2020-01-30 00:00:00
abstract:Objective:With the aim of developing a chronic pain prevention program, this randomized controlled trial examined whether exercise training combined with increased physical activity more effectively improves pain and physical activity than exercise training alone in community-dwelling older adults without chronic pain....
journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
doi:10.1155/2018/2132039
更新日期:2018-04-05 00:00:00