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Lithium in combination with perphenazine: effect on plasma monoamine metabolites.

Abstract：

:The addition of lithium to perphenazine altered the pattern of plasma homovanillic acid (HVA) during the course of treatment for acute psychosis. In the perphenazine-treated group plasma HVA declined significantly by days 7-9 of treatment, whereas in the perphenazine-plus-lithium group plasma HVA tended to increase. The pattern for plasma methoxyhydroxyphenethyl-glycol (MHPG) was not significantly different for the two groups. The addition of lithium to a neuroleptic may enhance the metabolism of dopamine.

journal_name

Biol Psychiatry

journal_title

Biological psychiatry

authors

Bowers MB Jr,Mazure CM,Nelson JC,Jatlow PI

doi

10.1016/0006-3223(92)90190-b

subject

Has Abstract

pub_date

1992-12-15 00:00:00

pages

1102-7

issue

12

eissn

0006-3223

issn

1873-2402

pii

0006-3223(92)90190-B

journal_volume

32

pub_type

杂志文章

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