Abstract:
STUDY OBJECTIVE:To determine the applicability and reliability of a screening questionnaire to detect patients at high-risk of latex allergy; to assess the importance of other allergies such as profilin allergies (pollinosis) for presence of latex sensitization; and to determine the clinical effectiveness of preemptive avoidance of latex exposure in high-risk patients. DESIGN:Prospective, clinical trial. SETTING:Operative theater of a university hospital. PATIENTS:95 adult patients. INTERVENTIONS:Patients were preoperatively screened and classified for present latex allergy (high-risk and low-risk group) according to a specially designed screening questionnaire. Anesthesia and surgery in the high-risk group were performed strictly avoiding latex-containing materials. The low-risk group (other allergies including pollinosis) received routine treatment, without latex-avoidance. Effects of latex avoidance or exposure were evaluated by measuring specific IgE titers perioperatively. MEASUREMENTS AND MAIN RESULTS:According to the questionnaire, 45 patients at high risk were defined. Validity of classification of high-risk patients is supported by significantly higher total IgE and latex and grass profilin specific IgE compared to the low-risk group. There were no significant differences in other profilin-specific IgEs. In one case of severe anaphylactic reaction a drop of latex-specific IgE during surgery could be observed. CONCLUSION:The questionnaire allowed the identification of most patients at high risk for latex allergy. In isolated pollinosis no changes in any specific IgE levels were detectable. Strict avoidance of perioperative latex exposure in high-risk patients increases safety during anesthesia and surgery.
journal_name
J Clin Anesthjournal_title
Journal of clinical anesthesiaauthors
Haeberle HA,Lupic D,Midoro-Horiuti T,Kiefer RT,Schroeder TH,Unertl K,Dieterich HJdoi
10.1016/s0952-8180(03)00112-0subject
Has Abstractpub_date
2003-11-01 00:00:00pages
495-504issue
7eissn
0952-8180issn
1873-4529pii
S0952818003001120journal_volume
15pub_type
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journal_title:Journal of clinical anesthesia
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journal_title:Journal of clinical anesthesia
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abstract:STUDY OBJECTIVE:To measure the parameter of job satisfaction among anesthesiologists. DESIGN:Survey instrument. SETTING:Academic anesthesiology departments in the United States. SUBJECTS:320 anesthesiologists who attended the annual meeting of the ASA in 2009 (95% response rate). MEASUREMENTS AND MAIN RESULTS:The a...
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journal_title:Journal of clinical anesthesia
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journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,meta分析
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