Perioperative use of angiotensin-converting-enzyme inhibitors and angiotensin receptor antagonists.

Abstract:

STUDY OBJECTIVE:Clinical repercussions of perioperative treatment with ACEIs/ARBs. DESIGN:Systematic review according to PRISMA statement. SETTING:Perioperative period. PATIENTS:29 studies 11 cases/cases series, 12 observational studies and 6 randomized studies. MEASUREMENTS:Arterial blood pressure differences, refractory hypotension, other comorbidities. MAIN RESULTS:The studies show different results regarding the topics measured. They are divided in the results regarding blood pressure, long term morbidities and effects in neuraxial anesthesia. CONCLUSIONS:Withholding AECI/ARBs on the morning prior to surgery could be recommended as a potentially effective measure, with a low level of evidence, in order to reduce the appearance of hypotension in the perioperative period of non-cardiac surgery.

journal_name

J Clin Anesth

authors

Vaquero Roncero LM,Sánchez Poveda D,Valdunciel García JJ,Sánchez Barrado ME,Calvo Vecino JM

doi

10.1016/j.jclinane.2017.04.018

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

91-98

eissn

0952-8180

issn

1873-4529

pii

S0952-8180(17)30134-4

journal_volume

40

pub_type

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