Abstract：
STUDY OBJECTIVE:To evaluate the effect of ketorolac tromethamine on coagulation using thromboelastography (TEG). DESIGN:TEGs were performed in each patient before and after ketorolac administration. Each patient's predrug results were used as control measurements for comparison with the postdrug results. SETTING:Medical center surgical unit. PATIENTS:Twenty ASA physical status I and II patients undergoing minor elective surgery; 12 healthy volunteers. INTERVENTIONS:TEGs were performed in all subjects before and 60 minutes after the intramuscular (IM) administration of ketorolac tromethamine 60 mg. Ten surgical patients were studied in the intraoperative period, and 10 surgical patients were studied in the postoperative period. The 12 healthy volunteers did not undergo a surgical procedure. MEASUREMENTS AND MAIN RESULTS:Specific parameters assessed from the TEGs were reaction time (R time), coagulation time (RK time), clot formation rate (angle of deflection), and maximum clot strength (maximum amplitude of deflection). Ketorolac administration did not cause statistically significant changes in these parameters in any of the three groups studied. CONCLUSIONS:IM administration of ketorolac tromethamine 60 mg did not significantly alter the speed of formation or viscoelastic strength of clots as measured by TEG. These results provide additional support for prior clinical studies confirming the safety of ketorolac administration in the perioperative period.
journal_name
J Clin Anesthjournal_title
Journal of clinical anesthesiaauthors
Reinhart DJ,Latson TW,Whitten CW,Klein KW,Allison PM,Patel Mdoi
10.1016/0952-8180(93)90018-asubject
Has Abstractpub_date
1993-05-01 00:00:00pages
216-20issue
3eissn
0952-8180issn
1873-4529pii
0952-8180(93)90018-Ajournal_volume
5pub_type
杂志文章abstract：:Meralgia paresthetica is a chronic pain syndrome that is extremely rare in the pediatric population. It is manifested by hypesthesia or pain in the distribution of the lateral femoral cutaneous nerve (LFCN) and is typically caused by entrapment as the nerve passes deep to the inguinal ligament. This sensory mononeurop...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2016.04.015
更新日期：2016-09-01 00:00:00
abstract：:We describe a case of mucoid impaction following nasotracheal intubation in a child with an upper respiratory infection that was successfully treated with a fiberoptic bronchoscope too large to pass through the endotracheal tube lumen. To the best of our knowledge, it is the first report in the anesthesia literature i...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/s0952-8180(98)00037-3
更新日期：1998-06-01 00:00:00
abstract：STUDY OBJECTIVE:To study patients' requirement for propofol dosages during the course of repeated deep sedation for electroconvulsive therapy (ECT). DESIGN:Prospective study. SETTING:Outpatient psychiatric clinic in a tertiary-care, university-affiliated, 1100-bed metropolitan hospital. PATIENTS:30 patients undergoi...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章
doi：10.1016/j.jclinane.2003.09.009
更新日期：2004-06-01 00:00:00
abstract：:We anesthesized a patient susceptible to malignant hyperthermia (MH) three different times by epidural anesthesia with different types of local anesthetics. His skinned fiber test showed a marked acceleration of calcium (Ca2+)-induced Ca2+ release (CICR). When ester type local anesthetic was used for ankle contracture...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/0952-8180(95)00204-9
更新日期：1996-03-01 00:00:00
abstract：:Severe uncompensated lactic acidosis manifesting during the pre-anhepatic stage of orthotopic liver transplant surgery is an uncommon event, but it poses serious concern because of the additional lactate production and impaired elimination by the liver that develops during the anhepatic and allograft reperfusion stage...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2009.07.013
更新日期：2010-09-01 00:00:00
abstract：:Arterial misplacement of the Swan-Ganz catheter occurs occasionally and usually can be easily detected. However, in some special clinical settings, the problem may become more complicated. We report a case of chronic obstructive pulmonary disease in which, because of severe hypoxemia, systemic hypotension, and pulmona...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/0952-8180(95)00032-d
更新日期：1995-06-01 00:00:00
abstract：STUDY OBJECTIVE:To determine whether the previously published relationship between anesthetic technique and rate of surgical site infections (SSIs) was influenced by institution specific effects. DESIGN:Retrospective Review of Quality Assurance and Hospital Epidemiology databases. SETTING:Metropolitan medical center....
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2014.04.015
更新日期：2014-12-01 00:00:00
abstract：STUDY OBJECTIVE:To evaluate the efficacy of thoracic epidural analgesia (TEA) in scoliosis surgery. DESIGN:Descriptive clinical study. SETTING:University hospital. PATIENTS:15 ASA physical status I, II, and III patients undergoing thoracolumbar scoliosis correction. INTERVENTIONS:TEA was performed at three to 5 cm ...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2009.10.011
更新日期：2010-09-01 00:00:00
abstract：:Data on all obstetric patients delivering at the Brigham and Women's Hospital during the years 1982 through 1987 were collected. The anesthetic techniques used, the type and amount of anesthetic agents administered, and the postpartum relapse rate of multiple sclerosis patients were compared. Women who received epidur...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/0952-8180(88)90006-2
更新日期：1988-01-01 00:00:00
abstract：STUDY OBJECTIVE:To determine the effect-site target concentration (C(et)) of remifentanil that provides optimal conditions for patients and operators during cataract surgery during monitored anesthesia care using a target controlled infusion (TCI) of propofol and remifentanil. DESIGN:Prospective, randomized, double-bl...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jclinane.2010.02.007
更新日期：2010-11-01 00:00:00
abstract：STUDY OBJECTIVE:To study the impact of adding simulation-based education to the pre-intervention mandatory hospital efforts aimed at decreasing central venous catheter-related blood stream infections (CRBSI) in intensive care units (ICU). DESIGN:Pre- and post-intervention retrospective observational investigation. SE...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2012.04.006
更新日期：2012-11-01 00:00:00
abstract：:Obstructive sleep apnea (OSA) is associated with postoperative airway obstruction, hypoxemia, cardiac arrhythmias, cardiorespiratory arrest, hypoxic encephalopathy, and death. Three cases highlighting important issues in patients with OSA are presented that occurred prior to and after implementation of an OSA protocol...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2008.08.023
更新日期：2009-06-01 00:00:00
abstract：:This case report details the intraoperative course of a patient, in her early pregnancy, who had a cardiac arrest during transvaginal insufflation of carbon dioxide (CO2) for laparoscopic tubal ligation. Modern monitoring methods and their ability to detect gas embolism and aid in the diagnosis and treatment of this r...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/0952-8180(90)90068-e
更新日期：1990-03-01 00:00:00
abstract：STUDY OBJECTIVE:The aim of the study was to compare the incidence of the use of additional uterotonics before and after the change of carbetocin to oxytocin for the prevention of postpartum hemorrhage after cesarean delivery in women with severe preeclampsia. DESIGN:This was an observational retrospective before-and-a...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2016.08.017
更新日期：2016-12-01 00:00:00
abstract：:"A professor is a gentleman with a different point of view." This characteristic and sarcastic statement was often recited by August Bier (1861-1949) and can also be aptly applied to him. As the father of spinal and intravenous regional neural blockade, Bier had a tremendous impact on surgery and anesthesia. It took h...
journal_title：Journal of clinical anesthesia
pub_type： 传,历史文章,杂志文章
doi：10.1016/s0952-8180(00)00202-6
更新日期：2000-11-01 00:00:00
abstract：STUDY OBJECTIVE:To document the effects of compromised respiratory function on oxygen saturation (SpO2) after cesarean section via the telemetric pulse oximetry network (TPON) for 24 continuous hours. DESIGN:Prospective study. SETTING:Postpartum ward of a university hospital. PATIENTS:ASA physical status I or II par...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0952-8180(94)90009-4
更新日期：1994-03-01 00:00:00
abstract：:A 13-year-old girl with Goltz's (Goltz-Gorlin) syndrome (focal dermal hypoplasia) and cloacal exstrophy underwent day surgery cystoscopy. During the administration of inhalation anesthesia by mask, persistent partial upper airway obstruction was noted. Direct laryngoscopy unexpectedly showed variously sized verrucous ...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/0952-8180(91)90190-x
更新日期：1991-09-01 00:00:00
abstract：STUDY OBJECTIVE:Cesarean Delivery (CD) is a commonly performed obstetric procedure. Adding a regional anesthesia technique to multimodal analgesia in CD, may improve the quality of postoperative analgesia. In this study we evaluated the efficacy of Transversalis Fascia Plane Block (TFPB) for postoperative analgesia man...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2019.06.025
更新日期：2020-02-01 00:00:00
abstract：:Hemodynamic instability as a result of altered baroreflex mechanism is common in surgeries involving manipulation around the carotid sheath. We report a case in which hypertensive crisis was associated with laryngectomy during general anesthesia. Perioperative use of vasoactive agents such as alpha(2) agonists may hel...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2006.12.011
更新日期：2007-11-01 00:00:00
abstract：STUDY OBJECTIVE:To ascertain if coughing during emergence from general anesthesia can be suppressed with a modified endotracheal tube. DESIGN:Randomized, double-blind, controlled study. SETTING:Operating rooms at a university hospital. PATIENTS:46 adult ASA physical status I, II, and III patients requiring elective ...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0952-8180(01)00299-9
更新日期：2001-09-01 00:00:00
abstract：STUDY OBJECTIVE:To determine the cerebrospinal fluid (CSF): total plasma concentration ratio of ketorolac tromethamine following a single intramuscular (IM) dose. DESIGN:Open, single-dose, IM-administration study. SETTING:General operating theaters of a medical school hospital. PATIENTS:29 ASA physical status I and ...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/0952-8180(93)90061-i
更新日期：1993-11-01 00:00:00
abstract：:During transplant surgery, clot formation resulting in life-threatening thromboembolic phenomena or graft loss may be a consequence unless close monitoring of coagulation and anticoagulation treatment is instituted in a timely manner. Three cases with a hypercoagulable state, as determined by thrombelastography at the...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2009.10.021
更新日期：2011-02-01 00:00:00
abstract：STUDY OBJECTIVE:To investigate the effects of intravenous (IV) versus oral clonidine on alterations of heart rate (HR), mean arterial pressure (MAP), cardiac output (CO), and plasma-catecholamines due to endotracheal intubation. DESIGN:Randomized, double-blind, placebo-controlled study. SETTING:University hospital su...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/S0952-8180(97)00239-0
更新日期：1997-03-01 00:00:00
abstract：STUDY OBJECTIVE:To compare 4 different anesthesia induction protocols, in a simulated model of rapid-sequence induction, in controlled hypertensive patients. DESIGN:Prospective, randomized, double-blind, clinical investigation. SETTING:Large metropolitan university hospital. PATIENTS:120 ASA II-III adult hypertensiv...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jclinane.2005.06.006
更新日期：2006-02-01 00:00:00
abstract：STUDY OBJECTIVE:To evaluate the reliability of assessments of nasal flow rate for improved nostril selection for nasotracheal intubation. DESIGN:Prospective, randomized, double-blinded study. SETTING:Operating room of a university-affiliated hospital. PATIENTS:118 ASA physical status 1 and 2 patients, aged 18-65 yea...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jclinane.2011.08.006
更新日期：2012-06-01 00:00:00
abstract：STUDY OBJECTIVE:To determine whether a new Sonoclot-based, aprotinin-insensitive activated clotting time (aiACT) assay yields stable results over a broad range of aprotinin concentrations. DESIGN:Prospective trial conducted on in vitro blood samples. SETTING:Tertiary-care teaching medical center. PARTICIPANTS:19 hea...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/j.jclinane.2007.03.003
更新日期：2007-09-01 00:00:00
abstract：STUDY OBJECTIVES:To test the effect of stellate ganglion block on tympanic membrane temperatures. DESIGN:Prospective, observational study. SETTING:Department of Anesthesia, Yamanashi Medical University, Yamanashi, Japan. SUBJECTS:7 healthy male volunteers. INTERVENTIONS:Stellate ganglion block, 6 ml of 1% mepivacai...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章
doi：10.1016/s0952-8180(98)00092-0
更新日期：1998-12-01 00:00:00
abstract：STUDY OBJECTIVES:To study the effect of tracheal intubation or laryngeal mask airway (LMA) insertion on intraocular pressure (IOP) in strabismus patients undergoing balanced anesthesia with sevoflurane and remifentanil. DESIGN:Open, prospective, randomized study. SETTING:Tertiary care academic medical institution. P...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0952-8180(01)00259-8
更新日期：2001-06-01 00:00:00
abstract：STUDY OBJECTIVE:To investigate whether a novel ultrasound device may be used with a simplified augmented reality technique, and to compare this device with conventional techniques during vascular access using a vascular phantom. DESIGN:Prospective, randomized study. SETTING:Anesthesiology and Pain Medicine department...
journal_title：Journal of clinical anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jclinane.2014.02.010
更新日期：2014-09-01 00:00:00
abstract：STUDY OBJECTIVE:To compare postoperative nausea, emesis, analgesia, and recovery between propofol-ketamine and propofol-fentanyl in outpatient laparoscopic tubal ligations with general anesthesia. STUDY DESIGN:Prospective, randomized, blinded study. SETTING:Tertiary-care women's hospital. PATIENTS:120 ASA physical s...
journal_title：Journal of clinical anesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0952-8180(02)00391-4
更新日期：2002-09-01 00:00:00
