Treatment of severe lactic acidosis during the pre-anhepatic stage of liver transplant surgery with intraoperative hemodialysis.

Abstract:

:Severe uncompensated lactic acidosis manifesting during the pre-anhepatic stage of orthotopic liver transplant surgery is an uncommon event, but it poses serious concern because of the additional lactate production and impaired elimination by the liver that develops during the anhepatic and allograft reperfusion stages of the procedure. A man with end-stage liver disease secondary to hepatitis C and hemochromatosis and normal renal function, who developed severe lactic acidosis in the pre-anhepatic stage of liver transplantation, was treated successfully with intraoperative, continuous venovenous hemodialysis. Hemodialysis effectively corrected the patient's lactic acidosis and removed lactate, which contributed to hemodynamic stability during the anhepatic and graft reperfusion stages of his liver transplant surgery.

journal_name

J Clin Anesth

authors

Vitin A,Muczynski K,Bakthavatsalam R,Martay K,Dembo G,Metzner J

doi

10.1016/j.jclinane.2009.07.013

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

466-72

issue

6

eissn

0952-8180

issn

1873-4529

pii

S0952-8180(10)00237-0

journal_volume

22

pub_type

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